INTER-SITE QA DEVELOPMENT FOR THE FIRST BIRN

第一个诞生的站点间质量保证开发

• 批准号: 8169826
• 负责人: Gary H Glover
• 金额: $ 1.85万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169826
• 关键词: Biomedical Informatics Research Network; Calibration; Computer Retrieval of Information on Scientific Projects Database; Data; Development; Functional Imaging; Functional Magnetic Resonance Imaging; Funding; Grant; Institution; Meta-Analysis; Methods; Population; Population Study; Research; Research Personnel; Resources; Schizophrenia; Site; Source; Time; United States National Institutes of Health; hemodynamics; improved; programs; quality assurance; working group

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The FIRST (Functional Imaging Research Schizophrenia Testbed) Biomedical Informatics Research Network (fBIRN) program is the first-ever large scale, multi-center fMRI study of schizophrenia (http://www.nbirn.net). The fBIRN project will pool fMRI data from each of the 11 participating sites to enable the acquisition of a large and diverse study population in a modest time period. Our Center has been responsible for the calibration and quality assurance aspects important for multi-center fMRI trials, and G. Glover chairs the Calibration Working Group within the fBIRN. This subproject is a study of the use of breath holding (BH) to calibrate and mitigate the confounding effects of hemodynamic differences between subjects, thereby reducing variance and improving the ability to pool data across large populations. Previous activities have developed the basic method, which is in current use by the consortium.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 第一个（功能成像研究精神分裂症测试）生物医学信息学研究网络（FBIRN） 程序是有史以来第一个大规模的精神分裂症多中心功能磁共振成像研究（http://www.nbirn.net）。 FBIRN项目 将从11个参与站点中的每个站点中的每个站点汇总fMRI数据，以使大量多样的研究人群获得 在适度的时间段。我们的中心负责校准和质量保证方面对 多中心FMRI试验和G. Glover椅子校准工作组。 该副本是对呼吸持有（BH）的使用的研究 受试者之间的血流动力学差异，从而减少差异并提高汇集大型数据的能力 人群。以前的活动已经开发了基本方法，该方法目前是由财团使用的。