CLINICAL TRIAL: EFFICACY OF ANTIDEPRESSANTS IN CHRONIC BACK PAIN

临床试验：抗抑郁药治疗慢性背痛的疗效

• 批准号: 8166788
• 负责人: JOSEPH H ATKINSON
• 金额: $ 0.52万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166788
• 关键词: Absence of pain sensation; Acute; Antidepressive Agents; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Desipramine; Fluoxetine; Funding; Grant; Institution; Pain; Patients; Placebos; Research; Research Personnel; Resources; Safety; Source; United States National Institutes of Health; chronic back pain; depressive symptoms; disability; prospective; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Examine the acute efficacy and safety of desipramine alone compared to fluoxetine alone and to placebo in treating pain, disability and depressive symptoms in patients with chronic back pain. Develop prospective concentration-response curves for desipramine and fluoxetine analgesia.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 与单独的氟西汀相比，单独检查单独的去丙胺的急性功效和安全性，并在治疗慢性背痛患者的疼痛，残疾和抑郁症状方面进行安慰剂。开发前瞻性浓度 - 响应曲线，用于去丙氨酸和氟西汀镇痛。