RELATIONSHIP OF METABOLIC ABNORMALITIES TO HEPATIC STEATOSIS IN HUMAN

人体代谢异常与肝脂肪变性的关系

• 批准号: 8166550
• 负责人: RICHARD K. STERLING
• 金额: $ 0.87万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166550
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Development; Dyslipidemias; Fatty Liver; Fibrosis; Funding; Grant; HIV; Highly Active Antiretroviral Therapy; Human; Institution; Insulin Resistance; Lipodystrophy; Metabolic; Patients; Research; Research Personnel; Resources; Source; Steatohepatitis; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Long term HAART use is associated with insulin resistance (IR) and dyslipidemia, which can result in the development of hepatic steatosis and progressive steatohepatitis and fibrosis. To determine the relationship of insulin resistance (IR), lipodystrophy (LD), and HAART use to hepatic steatosis/NASH in HIV infected patients.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 长期使用HAART与胰岛素抵抗（IR）和血脂异常有关，这可能导致肝脂肪变性和进行性脂肪性肝炎和纤维化。 确定胰岛素抵抗 (IR)、脂肪营养不良 (LD) 和 HAART 使用与 HIV 感染患者肝脂肪变性/NASH 的关系。