HPV helper genes for AAV

AAV 的 HPV 辅助基因

• 批准号: 8337909
• 负责人: PAUL L HERMONAT
• 金额: $ 36.25万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2013-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8337909
• 关键词: ATP phosphohydrolase; Adenoviruses; Affect; Binding; Biochemical; Biochemistry; Biological Assay; Capsid; Cells; Clinical; Collaborations; Consensus; DNA Binding; DNA biosynthesis; Data; Dependovirus; Development; EMSA; Elements; Endonuclease I; Enhancers; Female; Funding; Future; Genes; Genital system; Genome; Goals; Grant; Health; Helper Viruses; Human; Human Papillomavirus; Human papillomavirus 16; Inverted Terminal Repeat; Knowledge; Length; Life Cycle Stages; Link; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Maps; Medicine; Parvovirus; Pharmaceutical Preparations; Production; Proteins; Protocols documentation; Recombinants; Reporting; Role; Safety; Simplexvirus; TCF3 gene; Tissues; Viral Vector; Virus; Virus Diseases; Virus Replication; gene function; gene therapy; helicase; improved; keratinocyte; knowledge base; mRNA capping; particle; transgene expression; vector; viral DNA

项目成果

AAV2 X increases AAV6 rep/cap-driven rAAV production.

• DOI: 10.1016/j.virol.2015.03.007
• 发表时间: 2015-08
• 期刊: Virology
• 影响因子: 3.7
• 作者: Cao M;Chiriva-Internati M;Hermonat PL
• 通讯作者: Hermonat PL

The X gene of adeno-associated virus 2 (AAV2) is involved in viral DNA replication.

• DOI: 10.1371/journal.pone.0104596
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Cao M;You H;Hermonat PL
• 通讯作者: Hermonat PL