Disposable Respiratory Flow Measurement Device

一次性呼吸流量测量装置

基本信息

批准号：
7539571
负责人：
BENJAMIN R LANE
金额：
$ 11.97万
依托单位：
KEY TECHNOLOGIES, INC.
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-15 至 2009-03-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7539571
关键词：
Accelerated Phase Accounting Adult Affect Air Ambulatory Monitoring Anesthesia procedures Appendix Applications Grants Area Baltimore Benchmarking Breathing Cannulas Child Childhood Chronic Obstructive Airway Disease Clinic Clinical Clinical Medicine Coin Consult Critiques Data Detection Development Devices Diagnosis Diagnostic Diagnostic Procedure Discipline Electronics Environment Environmental air flow Event Exhalation Face Failure Feedback Frequencies Funding Future Goals Gold Grant Home environment Hospitals Hour Human Humidity Hypercapnic respiratory failure Industry Knowledge Laboratories Longitudinal Studies Manufacturer Name Marketing Masks Measurement Measures Mechanics Medical Medicine Methods Mirage Modification Monitor Morphologic artifacts Motion Mouth Breathing Nose Numbers OSA Oral Patient Care Patient Monitoring Patients Pattern Performance Phase Physiological Plastics Play Polysomnography Population Positioning Attribute Procedures Production Public Health Published Comment Pulmonology Purpose Range Recommendation Relative (related person)Reproducibility Research Research Personnel Resistance Respiration Science Signal Transduction Sleep Sleep Disorders Standards of Weights and Measures System Techniques Technology Telephone Temperature Test Result Testing Tidal Volume Time Tooth structure Translating Tube Validation Variant Wireless Technology Work base commercialization computerized data processing concept cost day design face mask improved innovation meter milliliter performance tests pressure prototype research and development respiratory response sensor size success tool transmission process usability validation studies

项目摘要

DESCRIPTION (provided by applicant): The overall goal of this project is to develop, formally benchmark and validate a new flow sensor that will accurately quantify varying degrees of ventilation in pediatric and adult patient populations. The flow sensor is a simple, non-contact, disposable part that provides quantitative measurement of respiratory activity, even in the low-flow range. Current technologies lack the ability to accurately measure tidal volume but rather provide a semi-quantitative measure of respiratory patterns. A pneumotachograph (which can provide quantitative data) is too burdensome on patient comfort and breathing effort to obtain long term respiration measurements. Self-funded preliminary prototypes were developed prior to this grant submission and tested at the Johns Hopkins Sleep Disorders Center in Baltimore. The prototypes performed comparable to the gold standard (pneumotachograph). This project will finish development of the design, formally benchmark the flow sensor with the pneumotachograph, as well as examine the stability and accuracy of the design. Following this, the design will undergo planned improvements related to patient comfort and compliance. The project will conclude with formal clinical validation studies at overnight sleep clinics across a spectrum of patients to compare and validate the new flow sensor to current technology. Final design modifications will focus on optimization of a "plug-and-play" interface thereby simplifying integration with existing polysomnographic recording units and improving technician ease of use and patient comfort. The data and prototypes generated by this application will ultimately translate into improved care of patients that are susceptible to ventilatory failure and eventually as an ambulatory diagnostic system for patients in the home setting. This flow sensor will have an immediate impact on patient monitoring in sleep laboratories and will further influence diagnostic procedures in pulmonary medicine, anesthesia and other medical disciplines. PUBLIC HEALTH RELEVANCE: The proposed project will develop, formally benchmark and validate a new flow sensor that will allow the medical industry to accurately quantify ventilation. This flow sensor will measure a broad range of respiratory events, including subtle changes of breathing, in both pediatric and adult populations. Initially the flow sensor will be used as a diagnostic tool in the sleep lab environment, while future applications will include the flow sensor as a critical component of patient care in the hospital in-patient and ER as well as an ambulatory diagnostic tool for patients in the home setting.

描述（由申请人提供）：该项目的总体目标是开发、正式基准测试和验证一种新的流量传感器，该传感器将准确量化儿科和成人患者群体的不同通气程度。流量传感器是一种简单、非接触式、一次性部件，即使在低流量范围内也能定量测量呼吸活动。当前的技术缺乏准确测量潮气量的能力，而是提供呼吸模式的半定量测量。呼吸速度描记器（可以提供定量数据）对于患者的舒适度和呼吸努力来说过于繁重，无法获得长期的呼吸测量。自筹资金的初步原型是在提交赠款之前开发的，并在巴尔的摩的约翰·霍普金斯睡眠障碍中心进行了测试。原型的性能可与金标准（呼吸速度描记器）相媲美。该项目将完成设计开发，将流量传感器与呼吸速度描记器正式进行基准测试，并检查设计的稳定性和准确性。此后，该设计将进行与患者舒适度和依从性相关的计划改进。该项目将在夜间睡眠诊所对一系列患者进行正式的临床验证研究，以将新型流量传感器与当前技术进行比较和验证。最终的设计修改将侧重于“即插即用”界面的优化，从而简化与现有多导睡眠图记录装置的集成，并提高技术人员的易用性和患者的舒适度。该应用程序生成的数据和原型最终将转化为改善对易发生通气衰竭的患者的护理，并最终成为家庭患者的门诊诊断系统。该流量传感器将对睡眠实验室的患者监测产生直接影响，并将进一步影响肺科、麻醉科和其他医学学科的诊断程序。公共健康相关性：拟议项目将开发、正式基准测试和验证一种新的流量传感器，该传感器将使医疗行业能够准确量化通气量。该流量传感器将测量儿童和成人的各种呼吸事件，包括呼吸的细微变化。最初，流量传感器将用作睡眠实验室环境中的诊断工具，而未来的应用将包括流量传感器作为医院住院患者和急诊室患者护理的关键组成部分，以及患者的动态诊断工具。家庭设置。