MT VET COBRE II CORE A: ADMINISTRATIVE CORE

MT VET COBRE II 核心 A：管理核心

• 批准号: 8360158
• 负责人: MARK T QUINN
• 金额: $ 80.78万
• 依托单位: MONTANA STATE UNIVERSITY - BOZEMAN
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360158
• 关键词: Academy; Accounting; Administrative Personnel; Advisory Committees; Advocate; Animal Model; Animals; Antifungal Agents; Applications Grants; Bioinformatics; Candida; Cellular biology; Centers of Research Excellence; Collaborations; Committee Members; Communicable Diseases; Communication; Complement; Computers; Consultations; Core Facility; Country; Critiques; Cryptococcus; Data; Data Reporting; Development; Educational workshop; Elements; Emerging Communicable Diseases; Evaluation; Event; Faculty; Fostering; Funding; Goals; Grant; Health; Human; Human Resources; Immunity; Individual; Infection; Infectious Disease Immunology; Infectious Diseases Research; Laboratories; Leadership; Location; Manuscripts; Mentors; Modeling; Montana; National Center for Research Resources; National Institute of Allergy and Infectious Disease; Participant; Pathogenesis; Pathology; Performance; Persons; Pilot Projects; Principal Investigator; Program Development; Progress Reports; Reading; Recommendation; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resource Allocation; Resources; Review Committee; Schedule; Science; Scientist; Series; Services; Source; Structure; Students; Techniques; Telephone; The science of Mycology; Travel; United States National Academy of Sciences; United States National Institutes of Health; Universities; Visit; Washington; Work; Writing; base; biosafety level 3 facility; career development; computer network; cost; data exchange; experience; improved; interest; journal article; lectures; meetings; member; pathogen; professor; programs; research facility; symposium

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Administrative Core A is directed by Dr. Mark Quinn and includes all administrative staff and Mentors. Dr. Quinn provides administrative oversight, chairs the Executive Committee, and serves as a research advocate and coordinator of the scientific research conducted under COBRE II. The purpose of the Administrative Core is to provide administrative support and services to the PI, Mentors, Project Leaders (including the Developmental Projects), Supplemental Projects, new faculty hires, and all other investigators and technical personnel associated with the Center of Zoonotic and Emerging Infectious Diseases. It is through the efforts of this Core that all projects and Cores B & C of the Center are integrated and regularly assessed. The Administrative Core also includes an Administrative and Accounting Associate who organizes the COBRE events and conferences and provides fiscal management and support for all aspects of the program, and a Program Evaluator who collects and analyzes data and reports on the progress of the programs. As PI and scientific leader of COBRE II, Dr. Quinn is responsible for all aspects of the program. As such, his primary objective is to promote close and productive scientific interaction among the component Projects, Cores, and other Center investigators. This Objective is accomplished through several mechanisms. Research seminars presented by investigators from the component Projects and investigators of the Center are scheduled monthly. The emphasis of these seminars is to present work-in-progress so the researchers in the program are kept informed of the progress of other projects on a regular basis and so that constructive input can be provided to these investigators. These seminars are scheduled monthly and rotate between the projects. Dr. Quinn also seeks to facilitate effective collaborations among the projects by personally visiting individual investigators on a regular basis. This allows for direct discussions of the ongoing needs and integration of each particular project or Core within the Center. As PI, Dr. Quinn is particularly aware that there is an optimal distribution of services of the Cores to the component Projects in terms of allocation of resources and communication of data. The Administrative Core is comprised of several additional components. The Executive Committee (EC) includes the Program Director (PD), the Core Directors, which includes Drs. Quinn, Jutila, and Pascual, and Dr. Allan Harmsen who was the previous COBRE PI. The members of the COBRE II EC also served on the COBRE I Executive Committee, thus providing continuity for the program. The COBRE II PI (Quinn) chairs the EC, which met regularly during the reporting period. The EC developed strategies with the EAC, oversaw the development of workshops and lecture series, and reviewed the progress of the projects through biannual assessment reports from the Mentoring Board. The EC reviewed Core progress reports, set priorities for resource allocation, and made recommendations to the PI for future research directions. The External Advisory Committee (EAC) advises on scientific, administrative, and research elements of the COBRE Program. The COBRE II EAC is composed of Drs. John Perfect, Frank DeLeo, Eugene Butcher, and Guy Palmer (Chair of EAC). These scientists were asked to sit on the EAC because their expertise complements the Center and because of their extensive scientific, administrative, and mentoring experience. Dr. Palmer is a Professor, Director of the Washington State University Center for Global Animal Health, and a member of the National Academy of Sciences. He also serves on the Board of Directors of the Washington State Academy of Science. Dr. Frank DeLeo is a Senior Investigator, Acting Chief for the Laboratory of Human Bacterial Pathogenesis, and Chief of the Pathogen-Host Cell Biology Section at the National Institute of Allergy and Infectious Diseases, located at the Rocky Mountain Laboratories in Hamilton, MT. Dr. Butcher is a Professor of pathology at Stanford University and an internationally recognized expert in immunity to infectious disease. Dr. Perfect is a Professor and the Director of Mycology Research Unit at Duke University. Dr. Perfect's research team investigates anti-fungal agents in animal models of Candida and Cryptococcus infections. The EAC met with the EC by phone conference once this reporting year. The EAC was also in regular contact with the EC for grant proposal reviews for the Project Leaders and consultation regarding new hires. The EAC traveled to Montana and met in person with all Project Leaders, Mentors, and Core Directors. At this meeting, the EAC provided group assessment and critiques of progress of the individual components of COBRE II, as well as progress of COBRE II as a whole. Overall, the EAC was integral in reviewing the second-year performance of COBRE II and in providing longitudinal assessment of the program and individual research projects. The EAC provided concept development, program planning, research project development and mentoring, identification of resources, and evaluation of progress toward stated goals. In some cases, EAC members provided mentoring assistance to Project Leaders for grant proposal development and identified potential national mentors and collaborators. For Core A, the EAC's review was favorable. In their September evaluation, the EAC wrote: "The administrative core and overall direction of the program continue to be outstanding. In the past year, there has been a new faculty hire (Dr. Obar) and partial support for a new bioinformatics support person. The Research-in-Progress seminar series recommended by the EAC last year has been implemented and the external speaker series continues to be successful in attracting research leaders from throughout the country. The leadership is recognized and appreciated by the Project PIs." The Administrative Core organizes several programs to enhance research experiences and publicize the MSU COBRE Program, namely the national speaker series, participation in the National IDeA Conference (NISBRE) and Regional INBRE-COBRE Conferences, oversight of the Developmental Projects Program (formerly Pilot Projects Program), and support for the Bioinformatics Facility and Research within a cross-campus and interdisciplinary collaborative model. The national speaker series brings world-class infectious disease researchers to MSU campus. The COBRE-sponsored speakers tour labs at MSU and meet with COBRE researchers and students. These visits expose all faculty and students to cutting-edge science and provide informal review of ongoing research. COBRE students and faculty prepare for the seminars by reading journal articles and background science on the speakers' research prior to their visits. The annual research conferences and symposia are important venues that allow project leaders and other important researchers to showcase their research, interact with other researchers who share similar interests, and brainstorm new techniques and ways to expand or improve the science. Starting with COBRE II, the Pilot Projects were renamed as "Developmental Projects" This aspect of the Core still serves the same function. Namely, Developmental Grants provide vital funds for projects that have been successful in developing larger, federally-funded grants and fostering career development of junior investigators. Our COBRE Center is truly a center in terms of structure and proximity of most participants in one location. Indeed, this structure is facilitated by the fact that the entire Immunology and Infectious Diseases department is involved in the Center. The laboratories and offices of all COBRE Projects, two of the three Developmental Projects, all Cores, the PI and administrative personnel, and nine of the ten Mentors are located within the same building. In addition, this department operates the COBRE BSL-3 and ABSL-2 infectious disease research facilities, which are located within half a mile of the departmental research building. The close proximity of these investigators allows daily communications between investigators and facilitates coordination of interactions between the component projects and Cores. The third Developmental Project is located at UM, and the UM investigator travels to MSU once every other month for the Project Leader-Mentor meetings held concurrently with Center seminars. In addition, this investigator has full access to the Core facilities at MSU and UM, as well as to the BSL-3 facility located at MSU. Finally, the department of Immunology and Infectious Diseases maintains a computer network that interfaces with all computers at MSU. This network allows investigators to directly communicate with each other, including the transmission of data and manuscripts. Thus, this network also facilitates rapid and seamless communication between investigators and Mentors, including those at UM and the Rocky Mountain Laboratories.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 行政核心A由马克·奎因（Mark Quinn）博士指导，包括所有行政人员和导师。 Quinn博士提供行政监督，主席执行委员会，并担任根据Cobre II进行的科学研究的研究倡导者和协调员。 行政核心的目的是为PI，导师，项目负责人（包括发展项目），补充项目，新教师雇用以及与人畜共动性和新兴传染病中心相关的所有其他研究人员以及技术人员提供行政支持和服务。正是通过该核心的努力，将整合并定期评估该中心的所有项目和核心B＆C。行政核心还包括一个组织和会计助理，组织了工行事件和会议，并为该计划的各个方面提供财政管理和支持，以及一个计划评估员，他们收集和分析了有关计划进度的数据和报告。 作为PI和Cobre II的科学领导者，Quinn博士负责该计划的各个方面。因此，他的主要目标是促进组成项目，核心和其他中心研究人员之间的紧密和富有成效的科学互动。这 目标是通过多种机制实现的。组件项目和中心研究人员的调查人员举行的研究研讨会计划每月举行。这些研讨会的重点是展示进行中的工作，以便将计划的研究人员定期了解其他项目的进度，以便可以向这些研究人员提供建设性的投入。这些研讨会计划每月举行，并在项目之间旋转。 Quinn博士还试图通过定期亲自访问个人调查人员来促进项目之间的有效合作。这可以直接讨论中心内每个特定项目或核心的持续需求和集成。作为PI，Quinn博士特别知道，在资源分配和数据交流方面，将核心服务的服务最佳分配。 管理核心由几个其他组件组成。 执行委员会（EC）包括包括DRS在内的核心董事计划主任（PD）。 Quinn，Jutila和Pascual，以及以前的Cobre Pi的Allan Harmsen博士。 Cobre II EC的成员还曾在Cobre I执行委员会任职，从而为该计划提供了连续性。 cobre ii pi（Quinn）椅子EC，该主席在报告期间定期相遇。 EC通过EAC制定了策略，负责监督研讨会和讲座系列的开发，并通过指导委员会的双年度评估报告回顾了项目的进度。 EC审查了核心进度报告，为资源分配设定了优先级，并向PI提出了建议，以获取未来的研究方向。 外部咨询委员会（EAC）就柯布雷计划的科学，行政和研究要素提供建议。 COBRE II EAC由DRS组成。 John Perfect，Frank Deleo，Eugene Butcher和Guy Palmer（EAC的主席）。这些科学家被要求坐在EAC上，因为他们的专业知识与中心相辅相成，并且由于其广泛的科学，行政和指导经验。帕尔默（Palmer）博士是华盛顿州立大学全球动物健康中心的教授，主任，也是美国国家科学院的成员。 他还担任华盛顿州科学院董事会成员。弗兰克·德勒（Frank Deleo）博士是人类细菌发病机理实验室的高级研究员，代理，也是美国国家过敏和传染病研究所的病原体宿主宿主细胞生物学科目，位于马利山汉密尔顿的落基山实验室。 Butcher博士是斯坦福大学病理学教授，是国际公认的传染病免疫专家。 Perfect博士是杜克大学的教授兼真菌学研究部门的主任。 Perfect博士的研究小组调查了念珠菌和加密环球感染动物模型中的抗真菌药物。 EAC本报告年度一次通过电话会议与EC会面。 EAC还与EC定期接触项目负责人的赠款提案审查，并就新员工进行咨询。 EAC前往蒙大拿州，亲自与所有项目负责人，导师和核心董事见面。在本次会议上，EAC对Cobre II各个组成部分的进度以及整个Cobre II的进度提供了小组评估和批评。总体而言，EAC在审查Cobre II的二年级表现以及对计划和个人研究项目的纵向评估方面是不可或缺的。 EAC提供了概念开发，计划计划，研究项目开发和指导，资源识别以及对既定目标的进步评估。 在某些情况下，EAC成员为项目负责人提供了指导帮助，以开发赠款提案，并确定了潜在的国家导师和合作者。 对于核心A，EAC的评论是有利的。 EAC在9月的评估中写道：“该计划的行政核心和整体方向继续非常出色。在过去的一年中，有一个新的教师雇用（奥巴尔博士）和对新的生物信息信息支持人员的部分支持。去年，EAC推荐的研究中的生物信息会议系列已由EAC推荐的EACC推荐，并继续由外部演讲者群体认可，以众所周知的领导者在“吸引领导者”中获得了领导。 pis。” 行政核心组织了几个计划，以增强研究经验并宣传MSU COBRE计划，即国家演讲者系列，参加国家思想会议（NISBRE）（NISBRE）和区域inbre-Cobre-obre-obre-obre-obre-obre-obre-obre-obre-obre-bre-cobre会议，对发展项目计划（以前是飞行员项目）的监督，并支持BioInformitics Bacitials Intical和Crossing and crossdorrory and Interdicriaror和InterddiCliarriald和Interddicriarcirorn。 全国演讲者系列将世界一流的传染病研究人员带到MSU校园。 由MSU的Coobre赞助的扬声器旅游实验室，并会见了Cobre的研究人员和学生。 这些访问使所有教职员工都了解了尖端的科学，并对正在进行的研究进行了非正式的审查。 田园的学生和教职员工在访问之前就演讲者的研究阅读期刊文章和背景科学为研讨会做准备。 年度研究会议和专题讨论会是重要的场所，使项目负责人和其他重要的研究人员可以展示他们的研究，与具有相似兴趣的其他研究人员进行互动，并集思广益，以及扩展或改善科学的新技术和方法。 从Cobre II开始，试点项目被重命名为“发展项目”，这一方面的核心仍然具有相同的功能。 也就是说，发展赠款为成功开发更大的，联邦政府资助的赠款并促进初级调查人员的职业发展的项目提供了重要资金。 在一个位置的大多数参与者的结构和接近性方面，我们的毛线中心确实是一个中心。确实，整个免疫学和传染病部门都参与了该中心，这一事实促进了这种结构。所有毛to项目的实验室和办公室，三个发展项目中的两个，所有核心，PI和行政人员，以及十个导师中的九个位于同一建筑物内。此外，该部门运营着位于部门研究大楼半英里处的Cobre BSL-3和ABSL-2传染病研究机构。这些研究人员的密切接近允许研究人员之间的日常通信，并促进了组件项目与核心之间的相互作用的协调。第三个发展项目位于UM，UM调查员每隔一个月一次前往MSU参加与中心研讨会同时举行的项目负责人会议。此外，该研究人员还可以完全访问MSU和UM的核心设施，以及位于MSU的BSL-3设施。最后，免疫学和传染病系维护了一个与MSU所有计算机接口的计算机网络。该网络允许研究人员直接互相通信，包括数据和手稿的传输。因此，该网络还促进了调查人员与导师之间的快速而无缝的沟通，包括UM和落基山实验室。