Longtitudinal Diabetes Care

纵向糖尿病护理

• 批准号: 8062105
• 负责人: TOM A ELASY
• 金额: $ 13.87万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8062105
• 关键词: ARHGEF5 gene; Accounting; Address; Area; Award; Behavior; Behavioral; Blood Glucose Self-Monitoring; Caring; Case Management; Characteristics; Clinical Research Curriculum Award; Clinical Trials Design; Commit; Diabetes Mellitus; Diet; Doctor of Philosophy; Dose; Effectiveness; Endocrinology; Ensure; Environment; Faculty; Failure; Frequencies; Funding; Future; Glycosylated hemoglobin A; Goals; Grant; Individual; Insulin; Intervention; Journals; Knowledge; Lead; Maintenance; Medical Students; Medication Management; Medicine; Mentors; Mentorship; Methods; Minority; Modification; National Institute of Diabetes and Digestive and Kidney Diseases; Nature; Non-Insulin-Dependent Diabetes Mellitus; Nurses; Patients; Population; Primary Health Care; Productivity; Public Health; Publications; Randomized Clinical Trials; Randomized Controlled Trials; Relapse; Relative (related person); Research; Research Personnel; Research Training; Resources; Schedule; Self Care; Specific qualifier value; Subgroup; Training; Treatment Failure; Universities; Update; Work; arm; base; career; cost; design; diabetes control; diabetes education; disorder later incidence prevention; follow-up; glycemic control; improved; interest; intervention effect; prevent; primary outcome; professor; programs; skills; success; theories

DESCRIPTION (provided by applicant): The Candidate: Dr. Elasy is a tenured Associate Professor of Medicine at Vanderbilt University . Evidence of his success as a translational (T2) diabetes research mentor is primarily the productivity and external funding of his mentees (13 first authored publications by his mentees since 2004; one K23 funded application (2005) and one pending K23 application; one NIDDK minority supplement to his grant (R18 DK062258-03) and another minority supplement to the Vanderbilt Diabetes Research and Training Center (DRTC P60 DK020593-28). The Environment: The environment at Vanderbilt University is highly conducive to the conduct of POR and Vanderbilt has unequivocally committed to Dr. Elasy's career as both a translational diabetes researcher and mentor. Of note, Dr. Elasy's integration with the K30 program has given him access to mentees, especially minority faculty, outside of Endocrinology who have gone on to do focused research in Diabetes. The Research Plan: This proposal addresses a line of inquiry regarding an optimal "dose" of diabetes care required to sustain optimal longitudinal diabetes care. Employing a randomized clinical trial the study addresses four specific aims. 1)To assess the relative effectiveness of 3 management approaches, varying in intensity, for preventing glycemic relapse after acceptable glycemic control is achieved; 2)To determine patient characteristics and behaviors that are prospectively predictive of successful relapse prevention in order to better understand the target group most likely to respond to a given maintenance plan; 3)To determine prospectively the predictors of failure to prevent glycemic relapse so as to better identify subgroups in need of alternate maintenance strategies; 4)To determine the differences in activity cost between intervention arms using activity based accounting. The Mentoring Plan:ln addition to a weekly journal clubs that highlight the methodological aspects of research and two (one for medical students/residents/fellows and another for junior faculty) weekly work-in-progress sessions for translational diabetes investigators, Dr. Elasy outlines specific skills his mentees will acquire beyond the formal training that some will receive as a result of the MPH or MSCI degree that are available. Relevance to Public Health: This K24 accelerates and heightens our understanding of optimal strategies to control diabetes. It also provides mentorship support for those who will lead this effort in the future.

描述（由申请人提供）： 候选人：Elasy博士是范德比尔特大学的终身医学副教授。他作为转化（T2）糖尿病研究导师成功的证据主要是他的受训者的生产力和外部资金（13个自2004年以来首次由他的受训者撰写出版物；一项K23资助的申请（2005年）和一项待处理的K23申请；一个NIDDK的少数派对他的赠款进行了培训（R18 DK062222258-03）和另一个NIDDK培训（R18 dk0622258-03）和vandb （DRTC P60 DK020593-28）。糖尿病。采用随机临床试验，研究解决了四个具体目标。 1）评估3种管理方法的相对有效性，强度有所不同，以防止可接受的血糖控制后血糖复发； 2）确定前瞻性预测预防复发的患者特征和行为，以更好地了解最有可能响应给定维护计划的目标群体； 3）确定未能防止血糖复发的预测因素，以便更好地识别需要替代维护策略的亚组； 4）使用基于活动的会计确定干预组之间的活动成本差异。指导计划：LN增加每周的期刊俱乐部，突出了研究的方法论方面，其中两个（一项是针对医学生/居民/研究员，另一个用于初级教师），每周进行转化的糖尿病调查人员进行工作，Elasy博士概述了他的受训者在某些正式培训中获得的特定技能将获得一些正式培训，以至于有些人将获得MSSC或MSSC的结果。 与公共卫生的相关性：该K24加速并提高了我们对控制糖尿病的最佳策略的理解。它还为将来会领导这项努力的人提供指导支持。