Cancer Center Support Grant

癌症中心支持补助金

• 批准号: 8104839
• 负责人: MICHELLE M LE BEAU
• 金额: $ 9.99万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8104839
• 关键词: Adjuvant; American College of Surgeons Oncology Group; Biometry; Breast; Cancer Center Support Grant; Cancer Immunology Science; Cancer Research Project; Cancer and Leukemia Group B; Children' s Oncology Group; Clinical; Clinical Research; Clinical Trials; Collaborations; Contracts; Development; Evaluation; Flow Cytometry; Funding; Gene Expression Regulation; Genomics Shared Resource; Goals; Gynecologic Oncology Group; Hematopoiesis; Human; Image; Image Analysis; Imagery; Immunohistochemistry; Immunologic Monitoring; Individual; Institution; Interdisciplinary Study; Intestines; Magnetic Resonance Imaging; Malignant Neoplasms; Microscopy; Mission; Molecular Genetics; Monitor; Monoclonal Antibodies; Operative Surgical Procedures; Patients; Pharmacology; Phase; Phase III Clinical Trials; Population; Prevention; Protocols documentation; Radiation Therapy Oncology Group; Research; Research Personnel; Signal Transduction; Spectrum Analysis; System; Therapeutic; Transgenic Mice; U-Series Cooperative Agreements; University of Chicago Cancer Research Center; cancer risk; embryonic stem cell; human tissue; member; multidisciplinary; prevent; programs; tissue resource

DESCRIPTION (provided by applicant): The University of Chicago Cancer Research Center (UCCRC) is submitting this competitive renewal application for its Cancer Center Support Grant for years 33-37. The mission of the UCCRC is to elucidate the determinants of cancer, to develop cures for cancer, and to prevent cancer. Our cancer research programs emphasize translational and interdisciplinary research, and we pursue this goal by promoting collaboration among a diverse and dedicated team of outstanding basic, translational, clinical, and population researchers. The 198 members of the UCCRC are organized into six established programs, all with a translational focus (Cell Signaling and Gene Regulation; Molecular Genetics and Hematopoiesis; Immunology and Cancer; Clinical and Experimental Therapeutics; Advanced Imaging, and Cancer Risk and Prevention). Clinical research is a major focus of multidisciplinary activity at the UCCRC. In 2006, over 1000 individual patients were accrued to therapeutic protocols supported, in part, by NCI cooperative agreements and contracts to conduct phase I, phase II, and phase III clinical trials. The UCCRC is the host institution for the Cancer and Leukemia Group B, a full member of the Gynecologic Oncology Group, and the Children's Oncology Group, and participates in the Radiation Therapy Oncology Group, American College of Surgeons Oncology Group, and National Surgical Adjuvant Breast and Bowel Program studies. Funds are requested in this application for Senior and Program Leaders, Planning and Evaluation, Developmental Funds, Administration, Protocol-Specific Research, the Protocol Review and Monitoring System, and 13 shared resources (Genomics; Fitch Monoclonal Antibody; Flow Cytometry; Immunohistochemistry; Human Immunologic Monitoring; Integrated Microscopy; Magnetic Resonance Imaging and Spectroscopy; Scientific Visualization and Image Analysis; Transgenic Mouse/Embryonic Stem Cell; Human Tissue Resource; Pharmacology; Biostatistics; and Cancer Clinical Trials Office).

描述（由申请人提供）：芝加哥大学癌症研究中心 (UCCRC) 正在提交这份竞争性续签申请，以获得 33-37 年的癌症中心支持补助金。 UCCRC 的使命是阐明癌症的决定因素、开发癌症治疗方法并预防癌症。我们的癌症研究项目强调转化和跨学科研究，我们通过促进由杰出的基础、转化、临床和人口研究人员组成的多元化、专注的团队之间的合作来实现这一目标。 UCCRC 的 198 名成员分为六个既定项目，所有项目均以转化为重点（细胞信号转导和基因调控、分子遗传学和造血作用、免疫学和癌症、临床和实验治疗、高级成像以及癌症风险和预防）。临床研究是 UCCRC 多学科活动的主要焦点。 2006年，超过1000名患者接受了部分由NCI合作协议和合同支持的治疗方案，以进行I期、II期和III期临床试验。 UCCRC 是癌症和白血病 B 组的主办机构，是妇科肿瘤学组和儿童肿瘤学组的正式成员，并参与放射治疗肿瘤学组、美国外科医生学会肿瘤学组和国家辅助乳腺手术组和肠道计划研究。本申请要求为高级和项目领导、规划和评估、发展基金、管理、方案特定研究、方案审查和监测系统以及 13 个共享资源（基因组学；Fitch 单克隆抗体；流式细胞术；免疫组织化学；人类免疫监测；磁共振成像和光谱；转基因小鼠/胚胎干细胞；药理学；生物统计学；和癌症临床试验办公室）。