Administrative Core

行政核心

• 批准号: 8328002
• 负责人: JOEL Barry BASEMAN
• 金额: $ 19.45万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8328002
• 关键词: Acute; Adult; Advisory Committees; Allergic Disease; Asthma; Biochemistry; Budgets; Child; Chronic; Communication; Community Acquired Respiratory Distress Syndrome Toxin; Consultations; Development; Diagnostic; Effectiveness; Ensure; Epidemiology; Equipment; Ethics; Experimental Designs; Functional disorder; Funding; Funding Opportunities; Housing; IACUC; Immunology; Institutional Review Boards; Instruction; Lead; Leadership; Link; Lung; Manuscripts; Medical Students; Medicine; Microbiology; Modification; Monitor; Mycoplasma pneumoniae; National Institute of Allergy and Infectious Disease; Occupational activity of managing finances; Pathology; Pediatrics; Performance; Postdoctoral Fellow; Prevention; Progress Reports; Reagent; Relative (related person); Research; Research Infrastructure; Research Personnel; Resource Allocation; Resources; Role; Sampling; Schedule; Testing; Therapeutic; TimeLine; Toxin; Training; Work; cost effectiveness; data management; graduate student; meetings; member; novel diagnostics; novel therapeutics; programs; research study; symposium

The long term objectives of the San Antonio Asthma and Allergic Diseases Cooperative Research Center (SA-AADCRC) Administrative Core (AC) are: to provide leadership and overall coordination of the projects and cores that comprise the SA-AADCRC and to facilitate interactions between investigators and other NIAID-funded AADCRCs, so that cross-disciplinary expertise and test samples and reagents generated by projects and cores are shared for maximum impact and cost effectiveness. The major focus of the SAAADCRC application is to identify and elucidate the roles of Mycoplasma pneumoniae and its unique Community Acquired Respiratory Distress Syndrome ToXin (CARDS TX), a bona fide ADP ribosylating and vacuolating toxin, and link them to new-onset asthma, exacerbations of asthma, and long-term pulmonary dysfunction in children and adults. The membership of the SA-AADCRC includes investigators from the Departments of Biochemistry, Microbiology and Immunology, Medicine, Pathology, and Pediatrics and the AC will continue to support this closely knit and collaborative group and ensure that all obligations and timelines are achieved and that relationships and communication between the SA-AADCRC and NIAID and other NIAID-sponsored AADCRCs are efficient, helpful and collaborative. The AC specific aims are: assist in the overall management and coordination of activities ofthe SA-AADCRC among investigators and NIAID staff and other AADCRCs; meet regularly with project and core leadership and trainees (graduate and medical students, postdoctoral fellows and residents) to assess strategies and progress, needs and resource allocation; recommend modifications of experimental design and research direction in consultation with key investigators and NIAID; schedule regular in-house research conferences and work-in-progress sessions and internal and external speaker seminars; help in the financial management and re-budgeting of the respective CRC projects and cores; review manuscripts and progress reports; perform the day-to-day administrative activities in order to facilitate effectiveness of the SA-AADCCRC as well as of the entire NIAID-sponsored AADCRC members; and promote the transfer of translational information (diagnostics, therapeutics) to UTHSCSA, NIAID and potential industrial partners. Additional AC responsibilities will promote maximal usage of resources in order to develop new and novel diagnostics and therapeutics for the treatment and prevention of acute and chronic asthma and allergic diseases.

圣安东尼奥哮喘和过敏疾病合作研究中心的长期目标 （SA-AADCRC）行政核心（AC）是：提供项目的领导和整体协调 以及构成SA-AADCRC并促进研究人员与其他其他相互作用的核心 NIAID资助的AADCRC，因此跨学科专业知识和测试样品和试剂由 共享项目和核心，以获得最大的影响和成本效益。 Saaadcrc的主要重点 应用是识别和阐明支原体肺炎的作用及其独特 社区获得了呼吸窘迫综合征毒素（Cards TX），一种真正的ADP核糖酰化和 吸气毒素，并将其链接到新的哮喘，哮喘的加重和长期肺 儿童和成人功能障碍。 SA-AADCRC的成员包括来自 生物化学，微生物学和免疫学，医学，病理学和儿科的部门 AC将继续支持这个紧密的编织和协作小组，并确保所有义务和 达到了时间表，并在sa-aadcrc和niaid之间的关系和沟通 其他由NIAID赞助的AADCRC具有高效，乐于助人和协作。 AC具体目的是：协助 在调查人员和NIAID的SA-AADCRC活动的整体管理和协调中 工作人员和其他AADCRC；定期与项目和核心领导和学员会面（毕业生和 医学生，博士后研究员和居民）评估策略和进步，需求和资源 分配;建议与Key协商进行实验设计和研究方向的修改 调查人员和尼亚德；安排定期内部研究会议和进行工作的会议 以及内部和外部演讲者研讨会；帮助财务管理和重新预算 各自的CRC项目和核心；审查手稿和进度报告；每天执行 为了促进SA-AADCRC的有效性以及整个整个 NIAID赞助的AADCRC成员；并促进翻译信息的传递（诊断， 治疗），授予UTHSCSA，NIAID和潜在的工业伙伴。额外的交流责任将 促进资源的最大使用，以开发新的和新颖的诊断和治疗剂 治疗和预防急性哮喘和过敏性疾病。