Mechanisms of alcohol mediated organ and tissue damage

酒精介导的器官和组织损伤的机制

• 批准号: 8097691
• 负责人: Gyongyi Szabo
• 金额: $ 1.6万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-05 至 2012-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8097691
• 关键词: Alcoholism; Alcohols; Applications Grants; Arts; Biological; Biological Models; Biological Response Modifiers; Biomedical Research; Communities; Epigenetic Process; Evaluation; Journals; Mediating; Methodology; Methods; Organ; Peer Review; Publishing; Research; Research Personnel; Scientist; Series; Societies; Systems Biology; Tissues; Trees; alcohol effect; alcohol exposure; alcohol research; biomedical scientist; design; interest; meetings; novel; programs; stem cell biology; success; symposium

DESCRIPTION (provided by applicant): This R13 conference grant application seeks support for a series of tree conferences on the topic of "Alcohol as a modifier of biological responses". We propose to organize a one day Satellite meeting in conjunction with the annual conference of the Research Society on Alcoholism to feature specific topic related to the biological modifier effects of alcohol. In year 2008, the satellite will focus on the "Epigenetic effects of alcohol," in 2009 on "Alcohol-induced modulation of stem cell biology" and in year 2010 on "Systems biology approach to the effects of alcohol". The target audience is biomedical researchers in the alcohol field. There have been 3 previous Satellite meetings organized by our group partially with the support of a previous R13 grant application. These Satellite meetings were a great success demonstrated by increasing attendance by the scientific community and the evaluations we received from attendees. Considering that traditionally biomedical research has been underrepresented in the RSA scientific program, this satellite meeting filled a major gap in bringing biomedical scientists together in a constructive manner. The aim of these conferences is to bring together scientists in the alcohol field with biomedical interest through designing programs that overarch the tissue specific effects of alcohol and to provide a platform for introduction of new concepts, state of the art methodologies and interaction between alcohol researchers in different model systems. By bringing keynote speakers who are not involved in alcohol research we intend to attract these investigators to alcohol research and vice versa, by exposing alcohol researchers to novel concept and methods, we believe these meetings would provide a fruitful mechanism for advancing the field. Summary material of the meeting will be prepared by the organizers and will be published in a peer-reviewed journal

描述（由申请人提供）：此R13会议赠款申请寻求有关“酒精作为生物反应的修饰者”主题的一系列树木会议的支持。我们建议与酒精中毒研究协会年度会议一起组织一天的卫星会议，以与酒精的生物修饰效应有关的特定主题。在2008年，卫星将重点关注“酒精的表观遗传作用”，2009年对“酒精诱导的干细胞生物学调节”以及2010年对“系统生物学方法对酒精的作用的调节”。目标受众是酒精领域的生物医学研究人员。我们的小组以前的R13赠款申请的支持部分组织了3次以前的卫星会议。这些卫星会议取得了巨大的成功，这表明了科学界的出勤率增加以及我们从与会者那里获得的评估。考虑到RSA科学计划中传统的生物医学研究的代表性不足，这次卫星会议填补了以建设性的方式将生物医学科学家聚集在一起的主要差距。这些会议的目的是通过设计构建酒精组织特定影响的计划，并为引入新概念，艺术方法的状态和酒精研究人员之间的相互作用提供一个平台，从而使酒精领域的科学家在生物医学领域中融合在一起。通过引入不参与酒精研究的主题演讲者，我们打算通过将酒精研究人员暴露于新颖的概念和方法来吸引这些研究人员进行酒精研究，反之亦然，我们相信这些会议将为推进该领域提供富有成果的机制。会议的摘要材料将由组织者准备，并将在同行评审期刊上发布