Core 1 - Nanomaterials Synthesis, Fabrication, and Characterization

核心 1 - 纳米材料合成、制造和表征

基本信息

批准号：
8066921
负责人：
FRANCOIS C BANEYX
金额：
$ 31.02万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-24 至 2015-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8066921
关键词：
Aerosols Air Antibodies Arts Award Biochemistry Biomedical Engineering Biophysics Chemical Engineering Chemistry Communities Development Doctor of Philosophy Drug Delivery Systems Education Electrical Engineering Electron Microscope Engineering Equipment Faculty Foundations Future Generations Genome Graduate Education Home environment Housing Image Imaging Device In Vitro Institution Laboratories Lasers Ligands Liquid substance Measurement Methods Microbiology Microscope Mission Modification Mus Nanotechnology Pacific Northwest Pattern Physics Physiology Preparation Protein Engineering Proteins Quantum Dots Research Research Infrastructure Research Personnel Role Scanning Scanning Probe Microscopes Scanning Tunneling Microscopy Science Semiconductors Services Staining method Stains Surface System Technology Toxic effect Traineeship Universities Washington aqueous atomic layer deposition biomineralization career electron beam lithography experience fluorescence microscope graduate student in vivo instrument lithography member molecular imaging nanofabrication nanomaterials nanoparticle nanoscience professor programs tomography tool tool development transmission process

项目摘要

Functions of the Core This Core builds on the nanotechnology strengths at the University of Washington (UW), one of the oldest state-supported institutions of higher education on the west coast, and one of the preeminent research universities in the worid. The UW Center for Nanotechnology (CNT), directed by Professor Francois Baneyx, was established in 1997, and has more than seventy-five faculty members from the Departments of Chemistry, Physics, Bioengineering (e.g.. Prof. Gao), Chemical Engineering {e.g., Prof. Baneyx), Electrical Engineering, Materials Science and Engineering, Biochemistry, Genome Sciences, Physiology and Biophysics, and Microbiology. Its Ph.D. Program in Nanotechnology established through a National Science Foundation's Integrative Graduate Education and Research Traineeship (NSF-IGERT) award was the first of its kind in the nation; the program provides graduate students with excellent interdisciplinary education experiences in nanoscale science and technology and emphasizes career path development. CNT is also home to the NanoTech User Facility (NTUF), which provides the Pacific Northwest nanotechnology community with access to advanced characterization and nanofabrication equipment. In 2004, NTUF expanded its role to the national level by becoming one of 14 nodes in the National Nanotechnology Infrastructure Network (NNIN), an NSF sponsored network of 13 universities, whose mission is to establish the infrastructure for current and future research and education needs in nanoscience and nanotechnology. NTUF houses leading-edge instruments, that will be critical for the characterization of quantum dots (Qdots) discussed below. Imaging tools include a Leica inverted fluorescence microscope, a Renishaw inVia Confocal Raman Microscope, an FEI field emission SEM with electron beam lithography capability, a Vecco Nanoscope scanning probe microscope with scanning tunneling microscopy and liquid mode force-distance measurement capabilities, a Zeiss LSM510 laser scanning confocal microscope interfaced with an atomic force microscope, a Woollam imaging ellipsometer, and a recently acquired Tecnai 200 kV scanning transmission electron microscope (S/TEM) with tomography capability. Fabrication tools include soft lithography, a Nabity e-Beam lithography system in the SEM, an Oxford OpAL atomic layer deposition system and a Heidelberg maskless pattern writer. NTUF also performs in-house nanotechnology tool development by drawing on faculty research and expertise. In addition. Prof. Baneyx, Gao, and Yost also have state-of-the-art instruments in their own laboratories for nanoparticle fabrication, purification, and characterization (see investigator equipment lists). Within this framework, the proposed Core has the following specific functions: (1) Preparation of well-characterized and purified nanoparticles in sufficient quantities for the U19 projects; (2) Construction of an aerosol generation and nanoparticle carrier system for exposing air-liquid interface cultures (Project 1) and mice (Project 2) to Qdots.

核心功能该核心是基于华盛顿大学（UW）的纳米技术优势，这是西海岸最古老的州立高等教育机构之一，也是WORID中杰出的研究所之一。由Francois Baneyx指导的UW纳米技术中心（CNT）成立于1997年，拥有从化学部门的75名教职员工，物理学，生物工程（例如Gao教授），化学工程（例如Baneyx教授），电气工程，材料科学和工程，生物化学，基因组科学，生理学和生物物理学以及微生物学。它的博士学位通过国家科学基金会建立的纳米技术计划综合研究生教育和研究实习生（NSF-IGERT）奖是全国第一个此类奖项；该计划为研究生提供了纳米级科学和技术的出色跨学科教育经验，并强调了职业道路发展。 CNT也是纳米技术用户设施（NTUF）的所在地，该设施为太平洋西北纳米技术社区提供了高级表征和纳米制作设备的访问。 2004年，NTUF成为国家纳米技术基础设施网络（NNIN）的14个节点之一，NTUF将其角色扩展到了国家一级，这是NSF赞助的13所大学的NSF赞助网络，其使命是建立纳米科学和纳米技术的当前和未来研究和教育需求的基础设施。 NTUF容纳领先的仪器，这对于量子点的表征至关重要（QDOTS）至关重要在下面讨论。成像工具包括Leica倒荧光显微镜，Renishaw Invia共焦拉曼显微镜，具有电子束光刻功能的FEI场发射SEM，Vecco纳米镜扫描探针显微镜使用扫描隧道显微镜和液体模式距离测量能力，Zeiss LSM510激光扫描共聚焦显微镜与原子力显微镜相连， Woollam成像椭圆机和最近获得的Tecnai 200 kV扫描透射电子显微镜（S/TEM）具有断层扫描能力。制造工具包括柔软的光刻，SEM中的Nabity电子束光刻系统，牛津蛋白石原子层沉积系统和Heidelberg无掩模的图案作者。 NTUF还通过借鉴教师研究和专业知识来进行内部纳米技术工具开发。此外。 Baneyx，Gao和Yost教授在自己的实验室中还拥有最先进的仪器，用于纳米颗粒制造，纯化和表征（请参阅研究者设备清单）。在此框架内，所提出的核心具有以下特定功能：（1）为U19项目提供足够数量的特征和纯化的纳米颗粒；（2）构建用于暴露空气界面的气溶胶产生和纳米颗粒载体系统培养物（项目1）和小鼠（项目2）到QDOTS。