Tracking Symptoms during Chemotherapy via Online Patient Self-reporting

通过在线患者自我报告跟踪化疗期间的症状

• 批准号: 7922782
• 负责人: ETHAN M. BASCH
• 金额: $ 10万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7922782
• 关键词: Accounting; Address; Administrative Efficiency; Adverse event; Area; Award; Behavior; Behavior Therapy; Cancer Center; Cancer Patient; Caring; Client satisfaction; Clinical; Clinical Informatics; Clinical Research; Clinical Trials; Common Terminology Criteria for Adverse Events; Communication; Data; Data Collection; Data Quality; Detection; Documentation; Drug toxicity; Early Diagnosis; Electronics; Ensure; Evaluation; Exposure to; Feasibility Studies; Fostering; Funding; Goals; Gold; Health Services; Health Services Research; Industry; Internet; K-Series Research Career Programs; Life; Malignant Neoplasms; Measures; Medical Oncology; Memorial Sloan-Kettering Cancer Center; Mentors; Methods; Minority; Modeling; Monitor; Operative Surgical Procedures; Outcome; Outcomes Research; Participant; Patient Outcomes Assessments; Patient Self-Report; Patients; Process; Quality of life; Questionnaires; Randomized Controlled Clinical Trials; Reporting; Research; Research Ethics Committees; Research Personnel; Research Support; Screening procedure; Series; Serious Adverse Event; Symptoms; Testing; Time; Toxic effect; Treatment outcome; Work; base; cancer care; cancer therapy; career; career development; chemotherapy; design; experience; health related quality of life; improved; instrument; new technology; oncology; patient oriented; patient safety; programs; response; routine care; skills; symptom management; tool; treatment trial

DESCRIPTION (provided by applicant): This proposal envisions a comprehensive plan for the career development of Dr. Ethan Basch in cancer outcomes research. Through mentored research, coursework, and independent study, Dr. Basch will develop collaborative relationships and methodologic skills to support his research agenda in clinical informatics and patient symptom management. This work focuses on the use of novel technologies to improve symptom monitoring during cancer care and trials, specifically through the evaluation of patient- centered treatment models which integrate patient reported outcomes (PROs). Currently, it is not standard to use patients' own self-reported symptom information to monitor cancer care. Rather, clinicians are relied upon to elicit, filter and report this information - an approach which is mandated in NCI and industry-sponsored trials. This stands in contrast to quality of life or symptom research, in which PROs are standard. The overall objective of this research program is to explore the application of patient self-reporting to symptom monitoring in oncology treatment, as a possible new paradigm. The specific aims are: 1) to assess the feasibility of routinely collecting symptom PROs via the web during cancer care and trials; 2) to measure the relationship between patient and clinician symptom reporting using the standard U.S. instrument for this purpose, the NCI's Common Terminology Criteria for Adverse Events (CTCAE); and 3) to evaluate the impact of patient self-reporting on clinical and administrative outcomes. This agenda will be accomplished through a series of IRB-approved studies Dr. Basch has designed and is systematically conducting at Memorial Sloan-Kettering Cancer Center, as well as nested in multicenter NCI and industry-sponsored clinical trials. RELEVANCE: Patient self-reporting may increase the efficiency of clinical operations, foster early detection of serious adverse events, and improve patient satisfaction. Engaging patients as active participants in research and in their own care conveys the message that treatment tolerance is an important endpoint. This work will help determine how new technologies may be deployed to improve traditional models of care.

描述（由申请人提供）：该提案设想了癌症成果研究中Ethan Basch博士职业发展的全面计划。通过指导的研究，课程和独立研究，Basch博士将发展协作关系和方法论技巧，以支持其在临床信息学和患者症状管理方面的研究议程。这项工作着重于使用新型技术来改善癌症护理和试验期间的症状监测，特别是通过评估以患者为中心的治疗模型，这些治疗模型整合了患者报告的结果（PROS）。目前，使用患者自己的自我报告的症状信息来监测癌症护理不是标准的。相反，依靠临床医生来引起，过滤和报告此信息 - 这种方法是在NCI和行业赞助的试验中要求的方法。这与生活质量或症状研究相反，专业人士是标准的。该研究计划的总体目的是探索患者自我报告在症状监测肿瘤治疗中的应用，这是一种可能的新范式。具体目的是：1）评估在癌症护理和试验期间通过Web常规收集症状专业人的可行性； 2）为此目的，使用标准的美国仪器来衡量患者和临床医生症状之间的关系，NCI的不良事件的常见术语标准（CTCAE）； 3）评估患者自我报告对临床和行政结果的影响。该议程将通过Basch博士设计并系统地在纪念斯隆凯特林癌症中心设计和系统地进行，并在多中心NCI和行业赞助的临床试验中嵌套。相关性：患者自我报告可能会提高临床操作的效率，促进对严重不良事件的早期发现并提高患者满意度。将患者作为积极参与者参与研究，并在他们自己的护理中传达出治疗耐受性是重要终点的信息。这项工作将有助于确定如何部署新技术以改善传统的护理模型。