MRI STUDIES OF THE BRAIN IN HEALTH AND ILLNESS

健康和疾病状态下大脑的 MRI 研究

• 批准号: 7955771
• 负责人: BRADLEY S PETERSON
• 金额: $ 0.34万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7955771
• 关键词: Affective; Anxiety Disorders; Attention deficit hyperactivity disorder; Brain; Brain imaging; Clinical; Computer Retrieval of Information on Scientific Projects Database; Diagnostic; Disease; Disruptive Behavior Disorder; Functional disorder; Funding; Gilles de la Tourette syndrome; Grant; Hyperactive behavior; Institution; Magnetic Resonance Imaging; Modeling; Neurobiology; Obsessive-Compulsive Disorder; Pathological Gambling; Research; Research Personnel; Resources; Source; Substance Use Disorder; Symptoms; United States National Institutes of Health; computational anatomy; design; experience; inattention; neuropsychiatry; novel therapeutics; relating to nervous system; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will use functional MR brain imaging (fMRI) to understand better the neurobiology of neuropsychiatric disorders such as Tourette's syndrome, Obsessive-Compulsive Disorder (OCD), Attention Deficit Hyperactivity Disorder (ADHD), anxiety disorders, substance use disorders, pathological gambling, affective illness and disruptive behavior disorders. Clinical experience has shown that people with a serious neuropsychiatric disorder suffer most not from their primary diagnostic symptoms, but from their difficulties with impulse control, hyperactivity, inattention, and response inhibition. These problems cut across most diagnostic domains and are amongst the most frequent causes for clinical referral. By understanding the neural dysfunction involved in these disorders, we will be better able to design and assess the effects of new therapeutics.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究将使用功能性MR脑成像（fMRI）更好地了解神经精神疾病的神经生物学，例如Tourette综合征，强迫症（OCD），注意力缺陷多动障碍（ADHD），焦虑症，焦虑症，药物使用障碍，病理障碍，情感疾病疾病和破坏性行为疾病。临床经验表明，患有严重的神经精神疾病的人最不受其主要诊断症状的影响，而是由于脉冲控制，多动症，注意力不集中和反应抑制而遇到的困难。这些问题在大多数诊断域中切断，并且是临床转诊最常见的原因之一。通过了解这些疾病涉及的神经功能障碍，我们将能够更好地设计和评估新疗法的影响。