INTERGENERATIONAL TRANSMISSION OF ANTISOCIAL BEHAVIOR

反社会行为的代际传播

• 批准号: 7955634
• 负责人: ADRIAN RAINE
• 金额: $ 0.34万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7955634
• 关键词: 11 year old; 17 year old; 3 year old; Address; Age; Aggressive behavior; Arousal; Attention; Behavior; Behavioral; Biological; Cognitive; Computer Retrieval of Information on Scientific Projects Database; Conduct Disorder; Conflict (Psychology); Exercise; Family; Female; Funding; Generations; Grant; Influentials; Institution; Knowledge; Lead; Life Stress; Measures; Mental disorders; Modeling; Nutritional; Parenting behavior; Parents; Physiological; Prevention program; Prospective Studies; Psychophysiology; Psychosocial Influences; Research; Research Personnel; Resources; Running; Social Environment; Source; Spouses; Testing; United States National Institutes of Health; Violence; aged; anti social; computational anatomy; criminal behavior; design; intergenerational; male; novel; offspring; psychosocial; social; transmission process

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. While it is well-known that antisocial behavior runs in families, surprisingly little is known about the specific mechanisms by which it is transmitted from one generation to the next. While the intergenerational transmission paradigm is becoming increasingly influential in addressing this issue, very few such studies are prospective, include both parents, focus on early mechanisms, and address female as well as male antisocial behavior. Importantly, none to date have examined biological influences on transgenerational continuity and change, or how they interact with social factors in modulating the transmission of antisocial behavior. The proposed three-generation study attempts to address these gaps in knowledge by capitalizing on a novel design in which I ,795 males and females were tested on psychophysiological, behavioral, nutritional, and cognitive measures at age 3, while their first-generation parents were assessed on psychosocial influences. These second-generation three-year-olds are now aged 30 years and will be retested, together with their third-generation three-year-old offspring, on psychophysiological, psychosocial, cognitive, behavioral, parenting, and antisocial behavior measures. Both the second generation parent and their previously untested spouse will be tested on psychophysiological measures, together with measures of life stress, daily hassles, family conflict, mental illness, and criminal behavior. The study will also assess whether a nutritional, exercise, and educational enrichment from ages 3-5 years in 100 of the second generation subjects, which has lead to increased physiological arousal and attention at age 11 years and reduced conduct disorder at age 17 years, disrupts the intergenerational transmission of antisocial behavior from the second to third generations. It is thought that the study offers a truly unique opportunity to understand the unexplored issue of how biological influences interact with social contexts in either blocki ng or facilitating the intergenerational transmission of antisocial and aggressive behavior. This new knowledge, if further developed, could contribute to a new generation of more effective prevention programs for reducing antisocial and violent behavior.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 尽管众所周知，反社会行为在家庭中运行，但令人惊讶的是，对它从一代传播到另一代的特定机制知之甚少。尽管代际传播范式在解决这一问题方面变得越来越有影响力，但很少有这样的研究是前瞻性的，包括父母双方，专注于早期机制，并解决女性以及男性反社会行为。重要的是，迄今为止，还没有研究过生物学对跨代连续性和变化的影响，或者它们如何与社会因素相互作用在调节反社会行为的传播时如何相互作用。拟议的三代研究试图通过利用一种新颖的设计来解决这些知识中的这些差距，其中I，795名男性和女性在3岁时对心理生理，行为，营养，营养和认知指标进行了测试，而他们的第一代父母对心理社会的父母进行了评估。这些第二代三岁的孩子现在已有30岁的年龄，将在心理生理，心理社会，认知，行为，育儿和反社会行为指标上重新测试他们的第三代三年级后代。第二代父母及其以前未经测试的配偶都将在心理生理措施上进行测试，以及生命压力，日常麻烦，家庭冲突，精神疾病和犯罪行为的措施。该研究还将评估第二代受试者中100名3-5岁的营养，运动和教育富集是否会导致11岁的生理唤醒和注意力增加，并减少17岁时的行为障碍，破坏了第二代反社会行为的代代相传的传播。人们认为，这项研究提供了一个真正独特的机会，可以理解生物学影响如何与社会环境相互作用或促进反社会和侵略行为的代际传播的未开发问题。如果进一步发展，这种新知识将有助于新一代更有效的预防计划，以减少反社会和暴力行为。