UA Center for Systems Biology

UA 系统生物学中心

• 批准号: 7859549
• 负责人: Kathleen Dixon
• 金额: $ 33.17万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7859549
• 关键词: Agriculture; Animal Model; Applications Grants; Appointment; Area; Arizona; Arts; Bioinformatics; Biological; Biology; Biomedical Research; Cancer Center; Commit; Communities; Complex; Computational Biology; Data; Development; Disease; Faculty; Fostering; Funding; Gene Expression; Genomics; Goals; Grant; Hispanics; Homeostasis; Individual; Institutes; Institution; Interdisciplinary Study; Investigation; Joints; Medicine; Mentors; Microarray Analysis; Minority; Molecular and Cellular Biology; Native Americans; Pilot Projects; Population; Positioning Attribute; Proteomics; Recruitment Activity; Research; Research Personnel; Science; System; Systems Biology; Technology; Training; Underrepresented Minority; Universities; Woman; Writing; base; college; expectation; experience; genetic analysis; high throughput technology; human disease; macromolecule; member; multidisciplinary; prevent; programs

DESCRIPTION (provided by applicant): We propose to establish a Center for Systems Biology to promote the application of state of the art high- throughput technologies and further a multidisciplinary, systems approach to biomedical research at the University of Arizona. The existing strengths of the institution in the use of model organisms and genetic analysis forms a strong base on which to expand the investigation of fundamental questions in biology and medicine to incorporate a systems approach. This proposal focuses on the recruitment of key junior faculty who will provide expertise in systems biology, computational biology and bioinformatics to foster collaborative multidisciplinary research. This Center will be based in the Department of Molecular and Cellular Biology (MCB) in the College of Science and will interface with the Arizona Cancer Center in the College of Medicine, the iPlant Consortium in the College of Agriculture, and the Bio5 Institute. MCB has a tradition of collaborative research and successful recruitment of faculty who establish strong ties across campus. Furthermore, we have a strong record in the recruitment and retention of women faculty and we are committed to building a diverse faculty. Given the large Hispanic and Native American populations in Arizona, we are in a strategic position to build our minority faculty. We propose the following Specific Aims: 1. Recruitment: We propose the recruitment of two new faculty members who training and experience in the broad areas of systems biology, computational biology, bioinformatics, and/or 'omics approaches to biomedical research (e.g., genomics, proteomics, microarray analysis). We propose to place special emphasis on the recruitment of women and underrepresented minorities. 2. Mentoring: The new recruit will be assigned a mentoring committee that will provide advice and support concerning lab set-up, staff hiring, grant writing, tenure expectations, and any other assistance needed. 3. Pilot Projects: To quickly integrate the new faculty into the UA multidisciplinary scientific community, we propose a pilot project program in which collaborative projects involving the new investigator will be solicited from the broad scientific community on campus.

描述（由申请人提供）：我们建议在亚利桑那大学建立一个系统生物学中心，以促进最先进的高通量技术的应用，并进一步采用多学科、系统的方法进行生物医学研究。该机构在使用模式生物和遗传分析方面的现有优势为扩大生物学和医学基本问题的研究以纳入系统方法奠定了坚实的基础。该提案的重点是招聘关键的初级教师，他们将提供系统生物学、计算生物学和生物信息学方面的专业知识，以促进多学科合作研究。该中心将设在理学院分子和细胞生物学系 (MCB)，并将与医学院亚利桑那癌症中心、农学院 iPlant 联盟和 Bio5 研究所合作。 MCB 有着合作研究和成功招聘教师的传统，这些教师在校园内建立了牢固的联系。此外，我们在招聘和保留女教师方面拥有良好的记录，并且我们致力于建设多元化的教师队伍。鉴于亚利桑那州有大量西班牙裔和美洲原住民人口，我们在建设少数族裔教师方面处于战略地位。我们提出以下具体目标： 1. 招聘：我们建议招聘两名新教员，他们在系统生物学、计算生物学、生物信息学和/或生物医学研究组学方法（例如基因组学）等广泛领域接受过培训并具有丰富的经验、蛋白质组学、微阵列分析）。我们建议特别重视招募女性和代表性不足的少数群体。 2. 指导：新员工将被分配一个指导委员会，该委员会将提供有关实验室设置、员工招聘、资助写作、任期期望以及任何其他所需帮助的建议和支持。 3. 试点项目：为了快速将新教师融入亚利桑那大学的多学科科学界，我们提出了一个试点项目计划，其中将从校园内广泛的科学界征集涉及新研究者的合作项目。