Identifying and exploiting novel pharmacological targets for breast cancer

识别和开发乳腺癌的新药理学靶点

• 批准号: nhmrc : 1141008
• 负责人: Dr Felicity Davis
• 金额: $ 29.14万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-exploiting-novel-breast-cancer/1319356
• 关键词: Identifying; exploiting; novel; pharmacological; targets

Breast cancers are made up of different types of cancer cells, and not all cells contribute equally. A subset of cancer cells may be uniquely capable of driving tumor growth, rebuilding fatal tumors after therapy and establishing new tumors at distant sites. Identifying and exploiting the pathways that regulate the activity and survival of these cells will lead to better modes of treatment, and move towards a relapse-free future for breast cancer patients.

乳腺癌由不同类型的癌细胞组成，并非所有细胞的作用均等。癌细胞的一个子集可能具有独特的能力，可以驱动肿瘤生长，在治疗后重建致命的肿瘤，并在远处建立新的肿瘤。识别和利用调节这些细胞的活性和存活的途径将带来更好的治疗模式，并为乳腺癌患者迈向无复发的未来。