Ankle strengthening using virtual reality and robotic dynamometer for CP patients

使用虚拟现实和机器人测力计对脑瘫患者进行踝关节强化

• 批准号: 7267927
• 负责人: Grigore C BURDEA
• 金额: $ 14.57万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7267927
• 关键词: Ankle; Baclofen; Behavior; Botulinum Toxins; Caliber; Canis familiaris; Cerebral Palsy; Characteristics; Child; Clinic; Clinical; Computer software; Custom; Data; Data Reporting; Databases; Devices; Dorsal; Environment; Evaluation; Exercise; Exertion; Feedback; Gait; Goals; Graph; Health Care Costs; Hour; Impairment; Internet; Intervention; Investigation; Joints; Knee; Little' s Disease; Local Therapy; Measures; Mechanics; Monitor; Motion; Movement; Muscle; Muscle Weakness; Nature; Online Systems; Patients; Performance; Persons; Pilot Projects; Positioning Attribute; Procedures; Process; Protocols documentation; Public Health; Purpose; Quality of life; Questionnaires; Randomized; Rate; Rehabilitation therapy; Reporting; Research Personnel; Resistance; Rhizotomy procedure; Risk; Robot; Robotics; Rutgers Ankle; Sampling; Series; Shapes; Skeletal system; Stretching; System; Time; Today; Torque; Training; Training Programs; United States National Institutes of Health; Universities; Video Games; Week; base; clinical research site; computerized; design; gait examination; improved; orthotics; patient safety; post stroke; programs; prototype; research clinical testing; simulation; strength training; success; virtual; virtual reality; web-accessible

DESCRIPTION (provided by applicant): We hypothesize that strengthening muscles may be an alternative for improving gait and function in children with cerebral palsy. Our long-term objective is to develop an improved strengthening therapy compared to today's approaches. Our proposed therapy is based on the use of a prototype Rutgers Ankle robot integrated with game-like virtual reality (VR) simulations. SPECIFIC AIMS The first aim is to develop the Rutgers Ankle CP for use in strengthening the ankles of children with CP. The second aim is to determine if a 12-week intensive ankle dorsi/plantarflexors strength-training program on the Rutgers Ankle CP will improve ankle strength, gait, function, and quality of life of children with CP. METHODS 1) we will construct the Rutgers Ankle CP system and modify the robot servo control to allow active assistance/passive resistance to ankle motion; 2) we will expand virtual rehabilitation software for children with CP training on the Rutgers Ankle CP. A new intelligent agent software will correlate task exertion requirements with patient past performance in order to determine the robot behavior (from 100% assistance to 100% resistance); 3) we will develop a web-accessible database module for reporting and data analysis. Data from the Rutgers Ankle CP will be sampled transparently in real time at the clinical site. Subsequently the data will be forwarded over the Internet to an existing database server at Rutgers University. The existing web-based clinical database and graphing environment will be enhanced to include conventional CP clinical evaluation measures, computerized variables from the VR exercises, and subjective evaluation questionnaires; 4) Six subjects with spastic diplegia CP will participate in a 12-week strength-training program of the ankle dorsi/plantarflexors on the Rutgers Ankle CP. Subjects will be evaluated for ankle strength, spasticity, gait analysis, GMFM, and Peds QL prior to the intervention, at the end of the 12-week intervention, and after an additional 12 weeks. We hypothesize that the subjects will improve in strength, gait, function, and quality of life from training on the robot, and will maintain the gains for at least 12 weeks. NIH RELEVANCE This project will develop a device for ankle strength training in CP. The strength training can be used to improve gait and function. PUBLIC HEALTH RELEVANCE A simple strength training program that improves gait and function will reduce health care costs by eliminating or delaying more expensive procedures.

描述（由申请人提供）：我们假设强化肌肉可能是改善脑瘫儿童步态和功能的替代方法。我们的长期目标是开发一种比当今方法改进的强化疗法。我们提出的疗法基于使用集成了游戏式虚拟现实 (VR) 模拟的罗格斯踝关节机器人原型。具体目标 第一个目标是开发 Rutgers Ankle CP，用于加强 CP 儿童的脚踝。第二个目标是确定罗格斯踝关节 CP 上为期 12 周的强化踝背/跖屈肌力量训练计划是否会改善 CP 儿童的踝关节力量、步态、功能和生活质量。方法1）我们将构建Rutgers Ankle CP系统并修改机器人伺服控制以允许主动辅助/被动阻力踝关节运动； 2) 我们将在 Rutgers Ankle CP 上扩展针对儿童 CP 训练的虚拟康复软件。新的智能代理软件将把任务执行要求与患者过去的表现联系起来，以确定机器人的行为（从 100% 协助到 100% 抵抗）； 3）我们将开发一个可通过网络访问的数据库模块，用于报告和数据分析。来自罗格斯 Ankle CP 的数据将在临床现场透明地实时采样。随后，数据将通过互联网转发到罗格斯大学现有的数据库服务器。现有的基于网络的临床数据库和绘图环境将得到增强，以包括传统的 CP 临床评估措施、VR 练习的计算机化变量以及主观评估问卷； 4) 六名患有痉挛性双侧瘫痪 CP 的受试者将参加罗格斯踝关节 CP 上为期 12 周的踝背/跖屈肌力量训练计划。在干预前、12 周干预结束时以及另外 12 周后，将对受试者的踝关节力量、痉挛、步态分析、GMFM 和 Peds QL 进行评估。我们假设受试者通过机器人训练将在力量、步态、功能和生活质量方面得到改善，并且将保持这种效果至少 12 周。 NIH 相关性 该项目将开发一种用于 CP 踝关节力量训练的设备。力量训练可用于改善步态和功能。公共卫生相关性 改善步态和功能的简单力量训练计划将通过消除或推迟更昂贵的手术来降低医疗保健成本。