UPMC McKeesport - ROCOG II - Sustained community clinical trial phase

UPMC McKeesport - ROCOG II - 持续社区临床试验阶段

• 批准号: 7754962
• 负责人: Dwight E Heron
• 金额: $ 25万
• 依托单位: UPMC MC KEESPORT
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7754962
• 关键词: Address; Advocacy; Cancer Center; Caring; Clinical Research; Clinical Trials; Collaborations; Communities; Community Clinical Oncology Program; Community Hospitals; Community Outreach; Diagnosis; Elderly; Eligibility Determination; Funding; Individual; Intervention; Leadership; Learning; Malignant Neoplasms; Mentors; Methodology; Modeling; Patients; Pennsylvania; Phase; Physicians; Population; Prevention; Process; Program Evaluation; Radiation Oncology; Recruitment Activity; Research Infrastructure; Research Personnel; Rivers; Screening procedure; Site; United States; Work; cancer health disparity; experience; patient oriented; programs; public health relevance; response; symptom management; treatment trial

DESCRIPTION (provided by applicant): This proposal is provided in two sections - Section I presents the final progress for the previously funded program, UPMC McKeesport Radiation Oncology Community Outreach and Section II details the implementation plan in response to CA-09-502. Building on experience and lessons learned from the clinical trials infrastructure project, the new plan provides for aggressive implementation which will involve several strategies: 1) Advanced tracking mechanisms for clinical trials screening using an NCI-approved methodology implemented by the Singing River CDRP site; 2) Initiation of a patient-centered model that provides support related to informed decision processes, interventions targeted at actual and perceived barriers to care working closely with the treating physicians and the clinical research coordinator (if recruited to trial); 3) Implementation of an investigator-initiated clinical trial with shorter treatment course that may be more appropriate for the elderly and other underserved individuals; 4) plans for collaboration with UPMC Cancer centers and other CDRP-funded sites to strategize and initiate application for CCOP program or similar consortium to sustain the programs beyond the funding period; and finally a commitment to serve as experts and mentors to other community sites serving disproportionate numbers of underserved in the United States. PUBLIC HEALTH RELEVANCE: The proposed project addresses disparate populations diagnosed with cancer in direct response to the funding announcement.

描述（由申请人提供）： 该提案分为两部分 - 第一部分介绍了先前资助的项目 UPMC McKeesport 放射肿瘤学社区外展的最终进展，第二部分详细介绍了针对 CA-09-502 的实施计划。基于从临床试验基础设施项目中汲取的经验和教训，新计划规定了积极的实施，其中将涉及多项策略： 1) 使用由 Singing River CDRP 站点实施的 NCI 批准的方法进行临床试验筛选的高级跟踪机制； 2) 启动以患者为中心的模式，与治疗医生和临床研究协调员（如果招募参加试验）密切合作，提供与知情决策过程、针对实际和感知的护理障碍的干预措施相关的支持； 3) 实施由研究者发起的临床试验，疗程较短，可能更适合老年人和其他服务不足的人群； 4) 计划与 UPMC 癌症中心和其他 CDRP 资助的机构合作，制定战略并启动 CCOP 计划或类似联盟的申请，以在资助期结束后维持该计划；最后，承诺担任其他社区网站的专家和导师，为美国大量服务不足的人群提供服务。 公共卫生相关性： 该拟议项目针对被诊断患有癌症的不同人群，以直接响应资助公告。