Substance use among adolescent and young adult Hispanic cancer survivors

青少年和年轻西班牙裔癌症幸存者的药物使用情况

• 批准号: 7811048
• 负责人: Joel E Milam
• 金额: $ 8.14万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-29 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7811048
• 关键词: Acculturation; Adolescent; Affect; Age; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Behavior; Behavioral; California; Cancer Survivor; Caring; Child; Clinical; Cohort Studies; Conflict (Psychology); Data; Development; Diagnosis; Drug usage; Education; Epidemiology; Ethnic group; Family; Funding; Funding Mechanisms; Gender; Goals; Health; Health Promotion; Health behavior; Health education; Hispanics; Hospitals; Income; Institutes; Knowledge; Late Effects; Life; Link; Los Angeles; Malignant Childhood Neoplasm; Malignant Neoplasms; Marijuana; Methods; Morbidity - disease rate; Neuraxis; Not Hispanic or Latino; Parents; Participant; Patients; Pediatric Hospitals; Population; Prevention Research; Psyche structure; Recommendation; Research; Research Personnel; Resources; Risk; Role; Stress; Students; Subgroup; Surveillance Program; Survival Rate; Survivors; Tobacco; Treatment-Related Cancer; Universities; Visit; Work; alcohol behavior; base; behavioral health; case control; childhood cancer survivor; cohesion; cohort; depression; depressive symptoms; design; disorder prevention; experience; follow-up; high school; improved; interdisciplinary collaboration; mortality; prevent; psychosocial; public health relevance; substance use prevention; young adult

DESCRIPTION (provided by applicant): Although treatment advances have increased the survival rates for childhood cancer, most survivors subsequently experience significant early life morbidity and mortality. Thus, childhood cancer survivors (CCS) are recommended to avoidance substance use (alcohol, tobacco, marijuana), to potentially delay or mitigate cancer treatment-related late effects. However, because prior work has been largely based on patients who were diagnosed before 1986, the extent of our knowledge regarding the health behaviors of recently treated CCS is unclear. Further, our understanding of Hispanic cancer survivors is especially limited due to under representation of this ethnic group in research efforts. The purpose of this study is identify risk and protective factors of substance use (alcohol, marijuana, and tobacco) among recently treated Hispanic and non-Hispanic CCS (ages 14-25), including cultural (e.g., acculturation to the U.S), psychosocial (e.g., stress), family (e.g., cohesion and conflict), and demographic (e.g., income, education) factors. To explore the potential impact of the cancer experience on substance use among Hispanics, rates of substance use between Hispanic CCS and age and gender matched non-cancer Hispanic controls (obtained from a separate cohort study of adolescents) will be compared. Results will guide the development of improved health education materials to prevent substance use among CCS, including potential unique approaches for Hispanic CCS. PUBLIC HEALTH RELEVANCE: The extent of our knowledge regarding the health behaviors of recently treated childhood cancer survivors (CCS) is unclear because prior work has been largely based on patients who were diagnosed before 1990. Further, our understanding of health behaviors among Hispanic cancer survivors is especially limited due to underrepresentation of this ethnic group in research efforts. The purpose of this study is to examine the substance use behaviors (alcohol, marijuana, and tobacco) of recently treated Hispanic CCS to provide vital information on appropriate methods to improve these behaviors and ultimately, long term survival of CCS.

描述（由申请人提供）：尽管治疗进展提高了儿童癌症的存活率，但大多数幸存者随后经历了显着的早期生命发病率和死亡率。因此，建议使用儿童癌症幸存者（CC）来避免使用药物（酒精，烟草，大麻），以延迟或减轻与癌症治疗相关的晚期作用。但是，由于先前的工作主要基于1986年之前被诊断出的患者，因此我们对最近治疗的CCS健康行为的了解程度尚不清楚。此外，由于这个族裔在研究工作中的代表下，我们对西班牙癌症幸存者的理解尤其受到限制。这项研究的目的是确定最近治疗的西班牙裔和非西班牙裔CCS（14-25岁）的风险和保护因素（酒精，大麻和烟草），包括文化（例如，对美国的适应性），心理社会（例如，心理社会（例如，压力）（例如，压力）（例如，压力），家庭（例如，（例如，coheion and Coheion and Copraphy），E。cohesion and copraphy coprication e. copraphy and Crompocraphion and Crompocraphip。为了探索癌症经验对西班牙裔药物中物质使用的潜在影响，将比较西班牙裔CCS与年龄和性别匹配的非癌症西班牙裔对照组（从单独的青少年研究中获得）的物质使用率。结果将指导改进的健康教育材料的开发，以防止CC之间的物质使用，包括西班牙裔CC的潜在独特方法。 公共卫生相关性：我们对最近治疗的儿童癌症幸存者（CCS）的健康行为的知识范围尚不清楚，因为先前的工作主要基于1990年之前被诊断出的患者。此外，由于这一族裔群体在研究工作中对西班牙裔癌症幸存者中的健康行为的理解尤为有限。这项研究的目的是检查最近处理过的西班牙裔CC的物质使用行为（酒精，大麻和烟草），以提供有关改善这些行为的适当方法的重要信息，以改善这些行为，并最终是CCS的长期存活。