Life Projects and Antiretroviral Therapy: The Social Impacts of Scale-up

生命项目和抗逆转录病毒治疗：扩大规模的社会影响

• 批准号: 7685812
• 负责人: Jennifer S Hirsch
• 金额: $ 64.76万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7685812
• 关键词: Adherence; Affect; Anti-Retroviral Agents; Applications Grants; Build-it; Caring; Case Study; Clinical; Collaborations; Collection; Communities; Complex; Consensus; Counseling; Couples; Data; Data Collection; Developed Countries; Developing Countries; Development; Disclosure; Disinhibition; Drops; Ensure; Ethnography; Family; Fertility; Funding; Gender; Goals; Grant; HIV; HIV Infections; Health; Human Resources; Individual; Inequality; International; Interview; Journals; Life; Longitudinal Studies; Manuscripts; Maps; Nature; Neighborhoods; New York City; Nigeria; Occupations; Papua New Guinea; Participant; Patients; Pharmaceutical Preparations; Phase; Policies; Population; Positioning Attribute; Preparation; Process; Protocols documentation; Provider; Publications; Recording of previous events; Reproductive Behavior; Research; Research Ethics Committees; Research Personnel; Research Project Grants; Risk; Sampling; Science; Services; Sex Behavior; Shapes; Site; Social Class; Social Impacts; Testing; Therapeutic; Time; Uganda; United States National Institutes of Health; Universities; Vietnam; Wages; Work; antiretroviral therapy; comparative; design; ethnographic method; experience; improved; instrument; peer; programs; protective behavior; reproductive; scale up; social; transmission process

We propose here a one-year planning grant to support the development of a competitive proposal to conduct comparative social scientific research on the experiences of individuals living with HIV. The proposed planning grant will intensify the start-up phase for the work proposed in grant application HD057792-01A2, accelerating the progress of the science proposed in that study. That comparative work would (1) examine and understand how the experience of ART affects family and peer relations, sexual behaviors, marital intentions and trajectories, and reproductive goals and practices; (2) investigate and evaluate how the intersection between ART and life projects shapes sexual and reproductive practices, adherence to treatment and care, and disclosure to social and sexual contacts; and (3) develop program strategies to enhance the clinical and population-level impacts. In this one year our specific aims would be: 1) To further develop the project’s conceptual framework; 2) To use that conceptual framework as a guide for the development of ethnographic instruments and sampling matrices; 3) To design and develop the necessary collaborations and community advisory panels ensuring both that the research contributes to the building of local research capacity and that it is framed by the buy-in of key stakeholders in order to maximize the translational impact of the research; 4) To build the capacity to apply for and receive IRB approval for the subsequent long term study, a complex process which requires the review of 10 separate institutional review boards, and 5) to prepare an application to NIH for funding as a competitive continuation to conduct comparative ethnographic study on the social impacts of the provision of anti-retroviral therapy.

我们在此提议一项为期一年的规划拨款，以支持有竞争力的发展 建议对个人生活经历进行比较性社会科学研究 拟议的赠款规划将加强赠款中拟议工作的启动阶段。 申请HD057792-01A2，加速了该研究中提出的科学进展。 比较工作将 (1) 检查并了解 ART 的经历如何影响家庭和同伴 关系、性行为、婚姻意图和轨迹以及生殖目标和实践 (2) 调查并评估 ART 与生活项目之间的交叉点如何影响性和生殖 (3) 发展实践、坚持治疗和护理以及公开社会和性接触； 增强临床和人群影响的计划策略 这一年我们的具体目标。 将是： 1) 进一步开发项目的概念框架； 2) 使用该概念框架作为 民族志仪器和抽样矩阵的开发指南 3) 设计和开发 必要的合作和社区咨询小组确保研究有助于 当地研究能力的建设，并由主要利益相关者的支持来构建，以最大限度地发挥 研究的转化影响； 4) 建设申请和获得 IRB 批准的能力 随后的长期研究，是一个复杂的过程，需要进行 10 项独立的机构审查 董事会，以及 5) 向 NIH 准备申请资金作为开展竞争性的延续 关于提供抗逆转录病毒治疗的社会影响的比较人种学研究。