Wearable Organic Electric Film RFID Sensors for Monitoring of Airborne Toxicants

用于监测空气中有毒物质的可穿戴有机电薄膜 RFID 传感器

• 批准号: 7652831
• 负责人: Radislav A Potyrailo
• 金额: $ 90.52万
• 依托单位: GENERAL ELECTRIC GLOBAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7652831
• 关键词: Air; Area; Biological; Calibration; Carbazoles; Charge; Chemicals; Communication; Complex; Consumption; Coupled; Data; Data Analyses; Data Collection; Detection; Development; Electronics; Elements; Environment; Exposure to; Film; Fluorenes; Frequencies; Gases; Home environment; Homo; Humidity; Knowledge; Measurement; Measures; Memory; Methodology; Monitor; Multivariate Analysis; Organic Synthesis; Polymers; Population Heterogeneity; Property; Protocols documentation; Radio; Reader; Reading; Relative (related person); Research; Side; Structure; Swelling; System; Technology; Time; Transducers; Variant; Water; Workplace; base; carbazole; chemical property; computerized data processing; conformational conversion; cost; density; design; digital; driving force; electric impedance; environmental chemical; experience; high throughput screening; innovation; meetings; member; molecular recognition; monitoring device; novel; portability; programs; prototype; public health relevance; response; sensor; skills; success; toxicant; transmission process; vapor; volatile organic compound; water vapor

DESCRIPTION (provided by applicant): Development of wearable sensors for point-of-contact, near-real time monitoring of exposure to environmental chemical species is critical to the success of studies of diverse populations. The demand for these sensors is driv- en by the yet unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption. In the proposed program, GE Global Research team will meet these require- ments for wearable sensors through the development of a new sensing platform that will dramatically decrease the complexity of accurate monitoring of airborne toxicants such as volatile organic compounds as well as re- ducing and oxidizing gases. The proposed sensor system will employ a novel sensing approach recently devel- oped at GE Global Research that utilizes resonant antenna structures of passive inductively coupled radio-fre- quency identification (RFID) sensors with organic electronic films that will serve as analyte-sensing coatings. This new sensing approach will provide selective quantitation of toxic volatile species with sub-ppm detection limits in presence of uncontrolled variations of ambient humidity. This response selectivity will be achieved not with an array of these sensors but with a single sensor. Such capability will be accomplished by capitalizing on (1) molecular recognition of gases by organic electronic polymers using several vapor-response mechanisms that act simultaneously, (2) new design of sensor transducer to fully probe these vapor-polymer interactions, and (3) standard multivariate analysis of the complex impedance response of the resonance sensor antenna structure. Developed sensors will be interrogated by a matchbox-sized, wearable sensor reader that will relate the findings to a local base station for a long-range transmission. The assembled research team has significant and recog- nized practical knowledge in chemical sensor design, synthesis of organic electronic polymers, low-power RF communications, and multivariate signal processing. This expertise will be coupled with key preliminary results that will facilitate the success of the proposed program. PUBLIC HEALTH RELEVANCE: An unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption is a strong driving force in the development of new sensing concepts. In the proposed pro- gram, the team will employ a novel sensing approach that utilizes resonant antenna structures of passive induc- tively coupled radio-frequency identification (RFID) sensors with organic electronic films that will serve as ana- lyte-sensing coatings. This new sensing approach will provide a wearable, cost-effective, selective sensor for de- tection of toxic volatile species.

描述（由申请人提供）：开发用于接触点、近实时监测环境化学物质暴露的可穿戴传感器对于不同人群研究的成功至关重要。对这些传感器的需求是由可穿戴传感器尚未得到满足的需求所驱动的，该需求需要以可忽略不计的功耗同时、选择性地测量多种分析物。在拟议的计划中，GE全球研究团队将通过开发新的传感平台来满足可穿戴传感器的这些要求，该平台将大大降低精确监测挥发性有机化合物等空气中有毒物质的复杂性，并减少和氧化性气体。所提出的传感器系统将采用GE全球研究中心最近开发的一种新颖的传感方法，该方法利用无源电感耦合射频识别（RFID）传感器的谐振天线结构以及有机电子薄膜作为分析物传感涂层。这种新的传感方法将在环境湿度发生不受控制的变化的情况下，以亚 ppm 的检测限对有毒挥发性物质进行选择性定量。这种响应选择性不是通过这些传感器的阵列来实现的，而是通过单个传感器来实现的。这种能力将通过以下方式实现：(1)有机电子聚合物使用多种同时作用的蒸汽响应机制对气体进行分子识别，(2)传感器换能器的新设计，以充分探测这些蒸汽-聚合物相互作用，以及(3)谐振传感器天线结构的复阻抗响应的标准多变量分析。开发的传感器将由火柴盒大小的可穿戴传感器读取器进行询问，该读取器将把结果与本地基站进行远程传输。组建的研究团队在化学传感器设计、有机电子聚合物合成、低功耗射频通信和多元信号处理方面拥有重要且公认的实践知识。这些专业知识将与关键的初步结果相结合，从而促进拟议计划的成功。公共健康相关性：可穿戴传感器以可忽略不计的功耗同时选择性地测量多种分析物的需求尚未得到满足，这是新传感概念开发的强大推动力。在拟议的计划中，该团队将采用一种新颖的传感方法，该方法利用无源电感耦合射频识别（RFID）传感器的谐振天线结构以及有机电子薄膜作为分析物传感涂层。这种新的传感方法将提供一种可穿戴、经济高效的选择性传感器，用于检测有毒挥发性物质。