Wearable Organic Electric Film RFID Sensors for Monitoring of Airborne Toxicants

用于监测空气中有毒物质的可穿戴有机电薄膜 RFID 传感器

• 批准号: 7652831
• 负责人: Radislav A Potyrailo
• 金额: $ 90.52万
• 依托单位: GENERAL ELECTRIC GLOBAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7652831
• 关键词: Air; Area; Biological; Calibration; Carbazoles; Charge; Chemicals; Communication; Complex; Consumption; Coupled; Data; Data Analyses; Data Collection; Detection; Development; Electronics; Elements; Environment; Exposure to; Film; Fluorenes; Frequencies; Gases; Home environment; Homo; Humidity; Knowledge; Measurement; Measures; Memory; Methodology; Monitor; Multivariate Analysis; Organic Synthesis; Polymers; Population Heterogeneity; Property; Protocols documentation; Radio; Reader; Reading; Relative (related person); Research; Side; Structure; Swelling; System; Technology; Time; Transducers; Variant; Water; Workplace; base; carbazole; chemical property; computerized data processing; conformational conversion; cost; density; design; digital; driving force; electric impedance; environmental chemical; experience; high throughput screening; innovation; meetings; member; molecular recognition; monitoring device; novel; portability; programs; prototype; public health relevance; response; sensor; skills; success; toxicant; transmission process; vapor; volatile organic compound; water vapor

DESCRIPTION (provided by applicant): Development of wearable sensors for point-of-contact, near-real time monitoring of exposure to environmental chemical species is critical to the success of studies of diverse populations. The demand for these sensors is driv- en by the yet unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption. In the proposed program, GE Global Research team will meet these require- ments for wearable sensors through the development of a new sensing platform that will dramatically decrease the complexity of accurate monitoring of airborne toxicants such as volatile organic compounds as well as re- ducing and oxidizing gases. The proposed sensor system will employ a novel sensing approach recently devel- oped at GE Global Research that utilizes resonant antenna structures of passive inductively coupled radio-fre- quency identification (RFID) sensors with organic electronic films that will serve as analyte-sensing coatings. This new sensing approach will provide selective quantitation of toxic volatile species with sub-ppm detection limits in presence of uncontrolled variations of ambient humidity. This response selectivity will be achieved not with an array of these sensors but with a single sensor. Such capability will be accomplished by capitalizing on (1) molecular recognition of gases by organic electronic polymers using several vapor-response mechanisms that act simultaneously, (2) new design of sensor transducer to fully probe these vapor-polymer interactions, and (3) standard multivariate analysis of the complex impedance response of the resonance sensor antenna structure. Developed sensors will be interrogated by a matchbox-sized, wearable sensor reader that will relate the findings to a local base station for a long-range transmission. The assembled research team has significant and recog- nized practical knowledge in chemical sensor design, synthesis of organic electronic polymers, low-power RF communications, and multivariate signal processing. This expertise will be coupled with key preliminary results that will facilitate the success of the proposed program. PUBLIC HEALTH RELEVANCE: An unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption is a strong driving force in the development of new sensing concepts. In the proposed pro- gram, the team will employ a novel sensing approach that utilizes resonant antenna structures of passive induc- tively coupled radio-frequency identification (RFID) sensors with organic electronic films that will serve as ana- lyte-sensing coatings. This new sensing approach will provide a wearable, cost-effective, selective sensor for de- tection of toxic volatile species.

描述（由申请人提供）：开发用于接触点的可穿戴传感器，几乎真实的时间监测环境化学物种的暴露对多种种群研究的成功至关重要。这些传感器的需求是通过尚未满足的可穿戴传感器同时且有选择地测量具有可忽略的功耗的多个分析物的需求。在拟议的计划中，GE全球研究团队将通过开发新的传感平台满足这些可穿戴传感器的要求，该平台将大大降低对机载有毒物质的准确监测的复杂性，例如挥发性有机化合物，以及重新探测和氧化气体。拟议的传感器系统将采用GE Global研究中最近开发的一种新型传感方法，该方法利用了有机电子膜的被动电感耦合无线电识别（RFID）传感器的共振天线结构，这些传感器将用作分析物的涂层涂层。这种新的传感方法将在存在不受控制的环境湿度变化的情况下对有毒挥发性物种进行选择性定量。这些响应选择性将不是使用这些传感器的数组来实现的，而是通过一个传感器来实现。这种能力将通过使用（1）通过（1）通过几种蒸气反应机制来利用（1）分子识别气体的分子识别，（2）传感器传感器的新设计，以充分探测这些蒸气 - 聚合物的相互作用，以及（3）复杂的抗势力响应的标准多变量分析，具有复杂的势力响应的结构。开发的传感器将受到火柴盒大小的可穿戴传感器读取器的询问，该读取器将将发现与当地基站进行远距离变速箱相关联。组装的研究团队在化学传感器设计，有机电子聚合物的合成，低功率RF通信和多元信号处理方面具有重要且具有认可的实践知识。该专业知识将加上关键的初步结果，这将有助于拟议计划的成功。公共卫生相关性：未满足的可穿戴传感器可以同时和选择性地测量具有可忽略的功耗的多个分析物，这是开发新传感概念的强大驱动力。在拟议的过程中，该团队将采用一种新型的传感方法，该方法利用具有有机电子膜的被动诱导型射频识别（RFID）传感器的共振天线结构，这些传感器将用作反应的涂料。这种新的传感方法将为有毒挥发性物种提供可穿戴，具有成本效益的选择性传感器。