HP/MICROSCOPY

惠普/显微镜

基本信息

批准号：
7535439
负责人：
RICHARD P WOYCHIK
金额：
$ 33.28万
依托单位：
JACKSON LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-07-01 至 2012-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7535439
关键词：
Autopsy Biological Biophysics Cancer Center Cancer Center Support Grant Chromosomes Confocal Microscopy Consult Cytogenetics Disease Electrons Ensure Faculty Fee-for-Service Plans Fluorescence Fluorescent in Situ Hybridization Grant Histology Histopathology Image Image Analysis Immunofluorescence Immunologic In Situ Hybridization Institutes Karyotype determination procedure Label Laboratories Laser Microscopy Life Microscopy Molecular Mus Normal tissue morphology Operative Surgical Procedures Pathologist Pathology Procedures Research Research Infrastructure Scanning Electron Microscopy Schedule Science Scientist Services Staining method Stains Standards of Weights and Measures Support System Technology Time Tissue Banks cellular imaging computerized cost follow-up functional genomics laser capture microdissection light microscopy member mutant tissue processing

Autopsy Biological Biophysics Cancer Center Cancer Center Support Grant Chromosomes Confocal Microscopy Consult Cytogenetics Disease Electrons Ensure Faculty Fee-for-Service Plans Fluorescence Fluorescent in Situ Hybridization Grant Histology Histopathology Image Image Analysis Immunofluorescence Immunologic In Situ Hybridization Institutes Karyotype determination procedure Label Laboratories Laser Microscopy Life Microscopy Molecular Mus Normal tissue morphology Operative Surgical Procedures Pathologist Pathology Procedures Research Research Infrastructure Scanning Electron Microscopy Schedule Science Scientist Services Staining method Stains Standards of Weights and Measures Support System Technology Time Tissue Banks cellular imaging computerized cost follow-up functional genomics laser capture microdissection light microscopy member mutant tissue processing

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项目摘要

The Histopathology & Microscopy Sciences (HPMS) Service offers Cancer Center members access to technologies and expertise in Histology, Necropsy, Electron Microscopy (scanning and electron), Light Microscopy and Cytogenetics. In combination with the Institute for Molecular Biophysics, HPMS delivers Cancer Center faculty unparalleled access to leading edge microscopy systems and the supporting infrastructure needed for the analysis and characterization of normal tissue morphology and mutant disease pathologies. Through HPMS Cancer Center, members access mouse necropsy, tissue collection, routine and specialized tissue processing and histological stains, immunofluorescence labeling, in situ hybridization, confocal microscopy, multiphoton microscopy, live-cell imaging, fluorescence and standard light microscopy, laser capture microdissection (LCM), computerized image analysis, and karyotyping and fluorescent in situ hybridization for chromosome analysis. HPMS (formerly Biological Imaging) has been supported by the CCSG grant for the past five years. The HPMS Project Leader, Research Scientist Dr. Richard Smith, oversees this fee-for-service operation. To further support the pathology analysis needs of the Cancer Center, access to Dr. Bronson, the Center's consulting Pathologist, and to all recommended follow-up procedures, are scheduled through HPMS. Six full-time histologists, two microscopists, three necropsy technicians, a cytogeneticist, consulting pathologist and senior manager staff the facility which occupies 3,772 ft2 of laboratory space in the Functional Genomics Building. Dr. Smith communicates with the Cancer Center users, Service staff and Center Administration to ensure that research needs are met in the most efficient, cost-effective and technically current manner.

组织病理学与显微镜科学（HPMS）服务为癌症中心成员提供了访问组织学，尸检，电子显微镜（扫描和电子）的技术和专业知识，光显微镜和细胞遗传学。与分子生物物理学研究所结合使用，HPMS提供癌症中心教师无与伦比的前缘显微镜系统和支持正常组织形态和突变体的分析和表征所需的基础设施疾病病理。通过HPMS癌症中心，成员进入小鼠尸检，组织收集，常规和专业组织加工和组织学染色，免疫荧光标记，原位杂交，共聚焦显微镜，多光子显微镜，活细胞成像，荧光和标准光显微镜，激光捕获显微解剖（LCM），计算机图像分析，核分型和荧光原位杂交用于染色体分析。 HPMS（以前在过去五年中，CCSG赠款支持生物成像）。 HPMS项目领导者，研究科学家理查德·史密斯（Richard Smith）博士负责监督这项按服务费用的行动。进一步支持癌症中心的病理分析需求，访问该中心咨询的布朗森博士病理学家以及所有建议的后续程序都是通过HPMS进行的。六个全职组织学家，两名显微镜学家，三名死灵症技术人员，一名细胞遗传学家，咨询病理学家和病理学家高级经理人员在功能基因组学中占据了3,772 FT2的实验室空间的设施建筑。史密斯博士与癌症中心用户，服务人员和中心管理确保以最有效，成本效益和技术目前的方式满足研究需求。