2007 Vascular Cell Biology Gordon Research Conference

2007年血管细胞生物学戈登研究会议

• 批准号: 7273048
• 负责人: Bradford C Berk
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-15 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7273048
• 关键词: 2007; Vascular; Cell; Biology; Gordon

DESCRIPTION (provided by applicant): Funds are requested to support the Gordon Research Conference on "Vascular Biology" to be held February 11-16, 2007 in Ventura, CA. The conference will cover a variety of topics including development of the vascular system, junctional communication, intracellular signaling, angiogenesis in reproduction, tissue specifications of vascular beds, proteases and matrix, and angiogenic and anti-angiogenic therapies. The meeting will bring together speakers, discussants and participants that represent a wide range of disciplines, approaches and systems. The small size of the conference and the informal atmosphere will facilitate discussion and interactions. Recent developments in the study of the control of vascular biology, such as inflammation and the use of systems biology make this a particularly timely meeting. SIGNIFICANCE: The study of vascular biology has been proceeding at a remarkable pace. Many new molecules relevant to vascular development and angiogenesis have been discovered in the last 2 years. These developments have applicability in many diseases including cancer, cardiovascular disease and inflammation. A timely review of the latest developments is essential in the fast moving field. APPROACH: The proposal will utilize the Gordon Conference format, which has been very successful, by providing an informal location and atmosphere that promotes scientific interactions. The relatively small size of the meeting (150 participants) and diversity of participants makes for an excellent exchange of ideas among both senior and junior investigators. The meeting will begin on a Sunday evening and end on Thursday. Each session is thematic and will be chaired by a Discussion Leader. A total of 31 speakers and 7 discussion leaders will be chosen. Topics include extracellular matrix signaling, apoptosis, vascular cell differentiation, tumor angiogenesis and tumor niches, endothelial cell junctions and permeability, immunology, vascular tube formation, and signaling transduction and integration. A listing of speakers and discussion leaders includes many of the leaders in the field (Iruela-Arispe, Hood, Nabel, Simons). In addition to lectures there will be posters selected from submitted abstracts. Only two posters per lab will be permitted to encourage diversity. A poster "contest" will also occur. The meeting is unique in its focus and size. Participants will be selected to provide a broad representation from all scientists including both clinical investigators and representatives from industry. Particular attention will be paid to women and minorities. The conference will be widely advertised and has a web site. Based on information from the previous meeting (esp. feedback from participants), and statistics regarding demographics of the previous participants, we have chosen topics and speakers to achieve diversity and address new areas (e.g. systems biology) within the field. The requested funds will be used to cover meeting fees and travel expenses of the speakers, chair and co-chair as well as 15 students and fellows. Total cost for the conference is estimated at $80,000 of which $23,500 will come from the GRC Chair's fund, $26,500 from industry and the remainder ($30,000) from the NIH. INVESTIGATORS: Bradford C. Berk, M.D., Ph.D., will be the principal investigator. He is an experienced organizer of Gordon Research conferences having chaired the Angiotensin II conference and serving as Vice-chair of the Vascular Biology conference in 2005. The Vice-chair, Michael Simons, M.D., will assist Dr. Berk in organizing and running the conference. ENVIRONMENT: The meeting site has excellent facilities in terms of audiovisual support, accessibility, quality of rooms and food, size of conference rooms, and many areas for interactions among speakers and participants. We believe this will be an excellent Gordon Research conference based on the timeliness of the subject matter, the excellence of the organization and program content, the excellence of the proposed speakers, and the meeting facilities.

描述（由申请人提供）： 请求资金支持将于 2007 年 2 月 11 日至 16 日在加利福尼亚州文图拉举行的戈登“血管生物学”研究会议。会议将涵盖各种主题，包括血管系统的发育、连接通讯、细胞内信号传导、生殖中的血管生成、血管床的组织规格、蛋白酶和基质以及血管生成和抗血管生成疗法。会议将汇集代表广泛学科、方法和系统的演讲者、讨论者和参与者。会议规模较小，气氛轻松，有利于讨论和互动。血管生物学控制研究的最新进展，例如炎症和系统生物学的应用，使这次会议变得特别及时。意义：血管生物学的研究一直在以惊人的速度进行。过去两年中发现了许多与血管发育和血管生成相关的新分子。这些进展适用于许多疾病，包括癌症、心血管疾病和炎症。在快速发展的领域，及时回顾最新发展至关重要。方法：该提案将利用非常成功的戈登会议形式，提供促进科学互动的非正式地点和氛围。会议规模相对较小（150 名参与者），参与者多样化，有利于高级和初级研究人员之间进行良好的思想交流。会议将于周日晚上开始，周四结束。每场会议均按主题进行，并由讨论负责人主持。共有31位演讲者和7位讨论主持人将被选出。主题包括细胞外基质信号传导、细胞凋亡、血管细胞分化、肿瘤血管生成和肿瘤微环境、内皮细胞连接和渗透性、免疫学、血管形成以及信号转导和整合。演讲者和讨论领导者名单包括该领域的许多领导者（Iruela-Arispe、Hood、Nabel、Simons）。除了讲座之外，还将展示从提交的摘要中选出的海报。每个实验室只允许张贴两张海报，以鼓励多样性。还将举办海报“竞赛”。这次会议的重点和规模都是独一无二的。参与者将被选为来自所有科学家的广泛代表，包括临床研究人员和行业代表。将特别关注妇女和少数民族。会议将广泛做广告并设有网站。根据上次会议的信息（特别是参与者的反馈）以及先前参与者的人口统计数据，我们选择了主题和演讲者，以实现多样性并解决该领域内的新领域（例如系统生物学）。所申请的资金将用于支付演讲者、主席和联合主席以及 15 名学生和研究员的会议费和差旅费。会议总费用估计为 80,000 美元，其中 23,500 美元将来自 GRC 主席基金，26,500 美元来自工业界，其余（30,000 美元）来自 NIH。调查员：Bradford C. Berk 医学博士、哲学博士将担任首席调查员。他是一位经验丰富的 Gordon Research 会议组织者，曾主持血管紧张素 II 会议，并于 2005 年担任血管生物学会议副主席。副主席 Michael Simons 医学博士将协助 Berk 博士组织和运行该会议。环境：会议场地在视听支持、可达性、房间和食物的质量、会议室的大小以及演讲者和参与者之间互动的许多区域方面都拥有优良的设施。我们相信，鉴于主题的及时性、组织和计划内容的卓越性、拟议演讲者的卓越性以及会议设施，这将是一次出色的戈登研究会议。