MICROSCOPY IMAGE ANALYSIS AND VISUALIZATION

显微图像分析和可视化

• 批准号: 7723095
• 负责人: ROSS T WHITAKER
• 金额: $ 4.62万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723095
• 关键词: Algorithms; Attention; Biomedical Technology; California; Cells; Chromosome Pairing; Collaborations; Communities; Computer Assisted; Computer Retrieval of Information on Scientific Projects Database; Computer software; Data; Funding; Goals; Grant; Head; Image; Image Analysis; Imagery; Institution; Macromolecular Complexes; Microscopy; Modality; National Center for Research Resources; Organelles; Range; Research; Research Personnel; Resources; Source; Structure; Synapses; Tissues; United States National Institutes of Health; Universities; image processing; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The National Center for Microscopy and Imaging Research (NCMIR), headed by Dr. Mark Ellisman at the University of California San Diego, is an NCRR NIH Biomedical Technology Research Center established to develop advanced, computer- aided microscopy for acquisition of structural and functional data. ¿The goal of the CIBC collaboration with NCMIR is to develop image analysis algorithms and software to help biomedical researchers understand structural and functional relationships within cells and tissues through a range of scales from macromolecular complexes to organelles and multi- component structures like synapses. ¿Several of our other collaborators have identified the extraction and analysis of cell geometry from microscopy data as a significant hurdle in their research, so the tools we develop with NCMIR are expected to be immediately useful to other researchers. ¿We feel that microscopy data has not received the same level of attention from the image processing community as many of the more clinically oriented imaging modalities and offers unique and important challenges. ¿With the NCMIR group, for example, we are developing tools for segmenting EMT data and constructing adaptive 3D meshes for release to the community.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以出现在其他 CRISP 条目中 列出的机构是。 中心，不一定是研究者的机构。 由马克·埃利斯曼 (Mark Ellisman) 博士领导的国家显微镜和成像研究中心 (NCMIR) 加州圣地亚哥是 NCRR NIH 生物医学技术研究中心，旨在开发先进的计算机技术 用于获取结构和功能数据的辅助显微镜。 CIBC 与 NCMIR 合作的目标是 开发图像分析算法和软件，帮助生物医学研究人员了解结构和功能 通过从大分子复合物到细胞器和多细胞的一系列尺度来研究细胞和组织内的关系 组件结构，如突触。我们的其他几位合作者已经确定了细胞的提取和分析 显微镜数据中的几何形状是他们研究的一个重大障碍，因此我们与 NCMIR 开发的工具是预期的 立即对其他研究人员有用。我们认为显微镜数据没有受到同等程度的关注 来自图像处理界的许多更面向临床的成像模式，并提供独特和 重要的挑战。例如，我们正在与 NCMIR 小组一起开发用于分割 EMT 数据和 构建自适应 3D 网格以发布给社区。