Wearable Nanosensor Array for Real-Time Monitoring of Diesel and Gasoline Exhaust

用于实时监测柴油和汽油尾气的可穿戴纳米传感器阵列

• 批准号: 7638914
• 负责人: ASHOK MULCHANDANI
• 金额: $ 9.97万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-15 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7638914
• 关键词: Air; Arsenic; Breathing; Burn injury; Carbon Dioxide; Carbon Monoxide; Carbon Nanotubes; Characteristics; Chemicals; Chromium; Collaborations; Communication; Complex Mixtures; Condition; Data; Data Collection; Detection; Device Designs; Devices; Diesel Exhaust; Disease; Electrodes; Electroplating; Engine Exhaust; Exposure to; Formaldehyde; Gases; Gasoline; Genetic Predisposition to Disease; Goals; Humidity; Hydrocarbons; Hydrogen Sulfide; Individual; Life; Link; Lung diseases; Malignant Neoplasms; Manganese; Measurement; Measures; Mercury; Metals; Monitor; Nanostructures; Nickel; Nitrogen Dioxide; Nitrous Oxide; Noise; Operative Surgical Procedures; Pattern; Performance; Polymers; Printing; Process; Radiation; Research; Research Personnel; Route; Scheme; Series; Side; Signal Transduction; Source; Staging; Sulfur Dioxide; System; Techniques; Teflon; Temperature; Testing; Time; Transistors; Validation; Variant; Wireless Technology; Zinc Oxide; analog; computerized data processing; data acquisition; digital; exhaust; hazard; improved; information gathering; light weight; metal oxide; multidisciplinary; nanosensors; particle; pollutant; polyaniline; polypyrrole; polythiophene; portability; programs; prototype; response; sensor; stannic oxide

Diesel and gasoline exhaust, produced when an engine burns fuel, is a complex mixture of gases and fine particles. Recent studies have linked respiratory diseases and cancer to exposure to gasoline and diesel exhaust. These diseases, however, are also attributed to genetic susceptibility. Establishing a direct linkage of these diseases to diesel and/or gasoline exhaust requires reliable and reproducible quantitative measure of exposure. The overall aim of the proposed collaborative research is to create, evaluate and validate an autonomous/self-contained wearable, approximately 4" by 4", sensor array for the real-time monitoring of exposure through inhalation to the gaseous components of internal combustion engine exhaust. The fully integrated light weight sensor that can be worn as badge similar to y-radiation counter will comprise an array of conductometric and amperometric sensors, and low-power fully integrated microelectronics for power management, data collection, and signal processing and wireless communications. Arrays of independent sensors can offer much more analytical information on personal exposure and thus hold a great potential for selective and accurate monitoring of low concentrations of mobile source air toxics and other relevant pollutants in real-time. The conductometric and amperometric platforms have strengths that are complementary to each other and are extremely 1Ccompatible. Advanced data processing will be used for generating distinct response patterns and detecting the individual compounds in gaseous mixtures. Such judicious integration of two powerful detection schemes along with an intelligent data processing should dramatically increase the gathered information on personal exposure to offer remarkable reliability along with broad scope, while meeting the portability requirements of decentralized detection systems. Our multidisciplinary expertise, extensive preliminary data and successful past collaboration lay the groundwork for the proposed activity. The overall goal will be realized by 1) developing, optimizing, characterizing and testing conductometric nanosensor array, 2) developing, optimizing, characterizing and testing microfabricated amperometric sensor array 3) developing integrated microelectronics for optimal power management, data collection and signal processing and remote communication, 4) integrating conductometric and amperometric sensor arrays in a single platform with incorporated microelectronics and 5) testing and validating the wearable sensor array by monitoring in real-time diesel and gasoline exhausts under realistic exposure conditions

当发动机燃烧燃料时会产生柴油和汽油排气，是气体的复杂混合物 颗粒。最近的研究将呼吸道疾病和癌症与汽油和柴油接触联系起来 排气。但是，这些疾病也归因于遗传敏感性。建立直接联系 这些疾病对柴油和/或汽油排气需要可靠且可重复的定量措施 暴露。 拟议合作研究的总体目的是创建，评估和验证 自主/独立的可穿戴设备，大约4“ x 4”，传感器阵列进行实时监视 通过吸入内燃烧引擎排气的气态组件的暴露。完全 可以穿着类似于Y辐射计数器的徽章的综合体重传感器将包含一个数组 导电传感器的电量和安培传感器以及低功率完全集成的微电子功率 管理，数据收集以及信号处理以及无线通信。独立阵列 传感器可以提供有关个人曝光的更多分析信息，从而具有很大的潜力 选择性，准确地监测低浓度的移动源空气毒物和其他相关的 实时污染物。导电和安培平台具有强度 彼此互补，并且极为1 coppat。高级数据处理将用于 产生不同的响应模式并检测气态混合物中的各个化合物。这样的 明智地集成了两个强大的检测方案以及智能数据处理 急剧增加有关个人接触的收集信息，以提供显着的可靠性 在满足分散检测系统的可移植性要求的同时，广泛的范围。我们的 多学科专业知识，广泛的初步数据和成功的合作奠定了基础 对于拟议的活动。 总体目标将通过1）开发，优化，表征和测试电导率 纳米传感器阵列，2）开发，优化，表征和测试微观制度的安培传感器 阵列3）开发用于最佳功率管理，数据收集和信号的集成微电子学 处理和远程通信，4）将电导率和安培传感器阵列集成 带有合并的微电子的单个平台和5）测试和验证可穿戴传感器阵列 在现实的暴露条件下实时柴油和汽油排气监测