A Regional, Multi-Institutional Academic Partnership for Excellence in EPHT

区域性、多机构学术合作伙伴关系，致力于在 EPHT 领域取得卓越成就

• 批准号: 7273639
• 负责人: DANIEL WARTENBERG
• 金额: $ 32.5万
• 依托单位: UNIV OF MED/DENT NJ-SCH OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-15 至 2010-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7273639
• 关键词: Regional; Multi; Institutional; Academic; Partnership

Environmental public health tracking (EPHT), a type of public health or epidemiologic surveillance, is the ongoing monitoring for and identification of local disease or injury excesses attributable to environmental hazards and the dissemination of these data for development of interventions to prevent and/or reduce the frequency and severity of these occurrences. This proposal seeks to undertake a regional, multi-institutional EPHT project to develop collaborations among neighboring EPHT Partners in the northeast US (e.g, Maine, New Hampshire, Massachusetts, Connecticut, New York and New York City) for surveillance and epidemiologic research, to demonstrate new applications and developments in methods for data linkage, pattern detection and assessment of exposure-disease associations, and to train students and other researchers in the use and interpretation of these approaches for the study of the possible environmental causes of disease. Specifically, in addition to conducting a review of current surveillance methodology, we plan to investigate and validate the addition of new data fields relevant to environmental problems to current reporting systems, such as birth certificates. We will review the current applications of ecologic analysis methods to EPHT, noting limitations and opportunities for improvement, develop training materials illustrating key points with concrete, non-mathematical logic and examples, and provide practical guidance for implementation. We also will explore new methods that exploit the spatial coherence of local environmental exposures, such as geographically weighted regression (GWR) and multivariate methods, conducting specific analyses to demonstrate their strengths and weaknesses for EPHT. We will work with EPHT partners to identify and develop a regional EPHT epidemiologic study focusing on a problem of local importance, such as the reproductive effects of exposure to arsenic in drinking water or air pollution, or assessment of the spatial pattern of childhood cancers and related environmental exposures. Initially, our focus will be on facilitating collaboration and data sharing while accommodating concerns about confidentiality. To provide guidance, we will convene an advisory committee of representatives from partner health agencies, partner environmental agencies, industry, NGOs and the public. We see these efforts as an important step from individual EPHT partner programs towards national EPHT network and collaboration.

环境公共卫生跟踪（EPHT）是一种公共卫生或流行病学监视，是持续的 监测和识别局部疾病或受伤的过度归因于环境 危害和传播这些数据以制定干预措施，以预防和/或减少 这些事件的频率和严重程度。该提案旨在进行区域多机构 EPHT项目旨在建立美国东北部邻近的EPHT合作伙伴之间的合作（例如，缅因州， 新罕布什尔州，马萨诸塞州，康涅狄格州，纽约和纽约市）进行监视和 流行病学研究，以证明数据链接方法中的新应用和发展， 模式检测和评估暴露 - 疾病协会，并培训学生和其他 研究人员的使用和解释这些方法用于研究可能的环境 疾病的原因。具体而言，除了对当前监视方法进行审查之外，我们还 计划调查和验证与环境问题相关的新数据字段的添加到当前 报告系统，例如出生证明。我们将审查生态分析的当前应用 EPHT的方法，指出局限性和改进的机会，开发培训材料说明 具有具体，非数学逻辑和示例的关键点，并为 执行。我们还将探索利用当地环境的空间连贯性的新方法 进行的暴露，例如地理加权回归（GWR）和多元方法 特定的分析以证明其EPHT的优势和劣势。我们将与EPHT合作 合作伙伴识别和开发一项区域EPHT流行病学研究，重点是本地问题 重要性，例如在饮用水或空气污染中暴露于砷的生殖影响，或 评估儿童癌症和相关环境暴露的空间模式。最初，我们的 重点将放在促进协作和数据共享的同时，以适应对 机密性。为了提供指导，我们将召集合伙人的众议员咨询委员会 卫生机构，合作伙伴环境机构，工业，非政府组织和公众。我们认为这些努力是 从单个EPHT合作伙伴计划到国家EPHT网络和协作的重要步骤。