Quantitative Chemical Biology(RMI)

定量化学生物学(RMI)

基本信息

批准号：
7483705
负责人：
TOBIAS MEYER
金额：
$ 26.84万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-30 至 2010-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7483705
关键词：
Academia Active Sites Address Admission activity Advisory Committees Algorithms Amino Acid Sequence Anabolism Area Award Belief Binding Biochemical Biochemistry Bioinformatics Biological Biology Biomedical Research California Categories Cell Communication Cell Lineage Cell physiology Cells Characteristics Chemicals Chemistry Chromosome Mapping Class Cluster Analysis Collaborations Commit Committee Members Communities Complex Computational Biology Computing Methodologies Consultations Country Critiques DNA DNA Structure Data Development Developmental Biology Developmental Process Diffusion Discipline Doctor of Philosophy Educational Curriculum Educational process of instructing Educational workshop Embryo Embryonic Development Ensure Environment Enzymes Equation Equilibrium Esthetics Evaluation Event Evolution Exercise Experimental Designs Faculty Failure Feedback Figs - dietary Fostering Foundations Fourier Series Funding Future Genetic Genetic Polymorphism Genetic Recombination Genome Genomics Goals Grant Group Meetings Growth Hand Haplotypes Home environment Homeostasis Hormonal Humanities Immunology Individual Industry Inorganic Chemistry Insecta Institutes Institution Interdisciplinary Study Journals Kinetics Knowledge Laboratories Laboratory Research Laws Lead Leadership Learning Left Legal patent Life Ligands Linear Programming Location Mammals Markov Chains Mathematics Membrane Mentors Mentorship Metalloproteins Metals Methods Modeling Molecular Molecular Models Monitor National Institute of General Medical Sciences Nature Nematoda Neurosciences Nucleotides Numbers Object Attachment Oral Oral Examination Organic Chemistry Organism Oxidation-Reduction Paper Participant Pathway interactions Peptide Sequence Determination Performance Persons Pharmacology Phosphorylation Physics Positioning Attribute Postdoctoral Fellow Principal Investigator Process Progress Reports Property Proteins Proteolysis Purpose Pyridoxal Qualifying Range Reaction Reading Reporting Research Research Activity Research Infrastructure Research Personnel Research Project Grants Research Proposals Resources Role Rotation Safety San Francisco Schedule Schools Science Scientist Sequence Analysis Series Services Signal Transduction Signal Transduction Pathway Site Solutions Solvents Staging Standards of Weights and Measures Statistical Models Structure Students Suggestion Synthesis Chemistry System Systems Biology Techniques Testing Thermodynamics Thinking Time Time Management Today Training Training Programs Training Support Tumor Biology Universities Update Visit Week Work Writing base biological research career chemical bond chemical synthesis cofactor computer science concept day design electrical potential experience falls frontier gene therapy genetic manipulation genome database genome sequencing improved innovation instructor interest macromolecule mathematical model medical schools member molecular dynamics molecular orbital next generation parent grant peer post-doctoral training posters practical application pre-doctoral programs prospective reconstruction solute statistics structural biology symposium theories tool

Academia Active Sites Address Admission activity Advisory Committees Algorithms Amino Acid Sequence Anabolism Area Award Belief Binding Biochemical Biochemistry Bioinformatics Biological Biology Biomedical Research California Categories Cell Communication Cell Lineage Cell physiology Cells Characteristics Chemicals Chemistry Chromosome Mapping Class Cluster Analysis Collaborations Commit Committee Members Communities Complex Computational Biology Computing Methodologies Consultations Country Critiques DNA DNA Structure Data Development Developmental Biology Developmental Process Diffusion Discipline Doctor of Philosophy Educational Curriculum Educational process of instructing Educational workshop Embryo Embryonic Development Ensure Environment Enzymes Equation Equilibrium Esthetics Evaluation Event Evolution Exercise Experimental Designs Faculty Failure Feedback Figs - dietary Fostering Foundations Fourier Series Funding Future Genetic Genetic Polymorphism Genetic Recombination Genome Genomics Goals Grant Group Meetings Growth Hand Haplotypes Home environment Homeostasis Hormonal Humanities Immunology Individual Industry Inorganic Chemistry Insecta Institutes Institution Interdisciplinary Study Journals Kinetics Knowledge Laboratories Laboratory Research Laws Lead Leadership Learning Left Legal patent Life Ligands Linear Programming Location Mammals Markov Chains Mathematics Membrane Mentors Mentorship Metalloproteins Metals Methods Modeling Molecular Molecular Models Monitor National Institute of General Medical Sciences Nature Nematoda Neurosciences Nucleotides Numbers Object Attachment Oral Oral Examination Organic Chemistry Organism Oxidation-Reduction Paper Participant Pathway interactions Peptide Sequence Determination Performance Persons Pharmacology Phosphorylation Physics Positioning Attribute Postdoctoral Fellow Principal Investigator Process Progress Reports Property Proteins Proteolysis Purpose Pyridoxal Qualifying Range Reaction Reading Reporting Research Research Activity Research Infrastructure Research Personnel Research Project Grants Research Proposals Resources Role Rotation Safety San Francisco Schedule Schools Science Scientist Sequence Analysis Series Services Signal Transduction Signal Transduction Pathway Site Solutions Solvents Staging Standards of Weights and Measures Statistical Models Structure Students Suggestion Synthesis Chemistry System Systems Biology Techniques Testing Thermodynamics Thinking Time Time Management Today Training Training Programs Training Support Tumor Biology Universities Update Visit Week Work Writing base biological research career chemical bond chemical synthesis cofactor computer science concept day design electrical potential experience falls frontier gene therapy genetic manipulation genome database genome sequencing improved innovation instructor interest macromolecule mathematical model medical schools member molecular dynamics molecular orbital next generation parent grant peer post-doctoral training posters practical application pre-doctoral programs prospective reconstruction solute statistics structural biology symposium theories tool

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项目摘要

DESCRIPTION (provided by applicant): Quantitative and chemical approaches to biomedical science are becoming increasingly important in the post-genomic era. Through the completion of multiple sequencing efforts, the scientific community has a panoramic view of nature's genetic 'parts', and it is now challenged with acquiring a functional knowledge of this complex machinery. Achieving this goal will require innovative approaches to biomedical research, and our next generation of scientists will therefore need training that seamlessly integrates quantitative, chemical, and biological methods. This application describes plans by Stanford University to create the Quantitative Chemical Biology (QCB) Program, an interschool initiative that will train predoctoral and postdoctoral students in interdisciplinary research. The QCB Program will be organized around several modules that include an interdepartmental graduate training program, a QCB Fellows program, specialized coursework, seminars and symposia, and two QCB faculty-directed facilities that will support post-genomic research projects. These activities and resources will establish a new paradigm for training young scientists, while synergizing with current programs at Stanford, such as the Bio-X initiative for multidisciplinary research. The University's ultimate goal is the creation of an interdepartmental, degree-granting QCB Program. In the interim, the Program will target students admitted to the Departments of Molecular Pharmacology and Chemistry who demonstrate an interest in interdisciplinary research, providing them with unrestricted access to nineteen QCB-affiliated laboratories in six academic departments. The QCB Program will also sponsor postdoctoral fellows who work collaboratively with two or more QCB-affiliated faculty members. Through these mechanisms, the QCB Training Program will support a diverse community that fosters interdisciplinary research and collaborative discovery, preparing future scientists for a scientific landscape without boundaries.

描述（由申请人提供）：生物医学科学的定量和化学方法在后的时代越来越重要。通过完成多个测序工作，科学界对自然的遗传“部分”有了全景观点，现在挑战了对这种复杂机械的功能知识。实现这一目标将需要创新的生物医学研究方法，因此，我们的下一代科学家将需要培训，以无缝整合定量，化学和生物学方法。该申请描述了斯坦福大学的计划，以创建定量化学生物学（QCB）计划，该计划是一项跨学业倡议，该计划将培训跨学科研究的杂物前和博士后学生。 QCB计划将围绕几个模块进行组织，其中包括部门间研究生培训计划，QCB研究员计划，专业课程工作，研讨会和座谈会，以及两个QCB教师指导的设施，这些设施将支持基因研究后的研究项目。这些活动和资源将为培训年轻科学家的新范式建立一个新的范式，同时与斯坦福大学的当前计划协同作用，例如BEIO-X多学科研究计划。该大学的最终目标是创建一个跨部门的QCB计划。在此期间，该计划将针对进入分子药理学和化学部门的学生，这些学生对跨学科研究表现出兴趣，从而使他们无限制地进入了六个学术部门的19 QCB附属实验室。 QCB计划还将赞助博士后研究员，他们与两个或更多QCB相关的教职员工合作。通过这些机制，QCB培训计划将支持一个培养跨学科研究和协作发现的多元化社区，为未来的科学家做好了科学景观，为没有界限的科学景观做好了准备。