AR CAREER DEVELOPMENT COBRE: PALLIATIVE STRATEGIES IN SPINAL CORD INJURY

AR 职业发展 COBRE：脊髓损伤的姑息策略

• 批准号: 7171353
• 负责人: Thomas S Kiser
• 金额: $ 34.73万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7171353
• 关键词: career; central nervous system; clinical research; educational resource design /development; health science profession; neuropathology

DESCRIPTION (provided by applicant): We will implement a Career Development Program for five Project Principal Investigators (PIs) who are close to nationally competitive levels using grant support and mentoring activities undertaken by established investigators. Each Project involves unique, innovative state-of-the-art research. The goal is to help these PIs secure mentored grants or R01 funding within 1-3 years, replacing them with other investigators close to nationally competitive levels, and helping those investigators secure extramural support. By the end of the award period, our goals are 1) to generate mentored grants and R01 funding for at least seven new investigators, and 2) to secure two additional multi-investigator awards. The Projects chosen have significant synergy, which will facilitate the third goal, 3) the submission of a Program Project application (P01) linking at least three of the new R01 awardees with other established investigators. We will also establish a multi-disciplinary Center for Translational Neuroscience (CTN) that will take advantage of the existing faculty strengths and expand the neuroscience research infrastructure, becoming a hub for campuswide collaborations. The CTN will also benefit from the recruitment of two tenure-track, mid- to senior-level, funded investigators who will also become mentors to Project PIs. In addition, three other faculty of junior rank will be recruited during the life of the award, adding to the critical mass of investigators. Additional potential future PIs will be recruited through a Pilot Study award program. The significant institutional commitment for this effort, will be parlayed into independent extramural support for the Center (P50 award) by the end of the award period. The Director of the CTN has experience with large-scale development programs, Program Project grants and has been Federally funded for over 20 years. We will establish a Core Facility and an Experimental Core, to provide an efficient means of ensuring that sophisticated and expensive instrumentation is fully utilized, maintained and operated by trained professionals. We will ensure that Project PIs have access to state-of-the-art services and facilities (through yearly purchases of new equipment), providing the basic underpinnings of the translational neuroscience research efforts at UAMS.

描述（由申请人提供）： 我们将利用现有研究人员开展的拨款支持和指导活动，为接近全国竞争水平的五名项目首席研究员 (PI) 实施职业发展计划。每个项目都涉及独特、创新的最先进研究。目标是帮助这些 PI 在 1-3 年内获得指导性资助或 R01 资助，用接近全国竞争水平的其他研究人员取代他们，并帮助这些研究人员获得外部支持。在奖励期结束时，我们的目标是 1) 为至少七名新研究人员提供指导资助和 R01 资金，2) 获得另外两项多研究人员奖励。所选项目具有显着的协同作用，这将促进第三个目标，3）提交计划项目申请（P01），将至少三名新的 R01 获奖者与其他已建立的研究人员联系起来。我们还将建立一个多学科的转化神经科学中心（CTN），该中心将利用现有的师资优势，扩大神经科学研究基础设施，成为全校范围内的合作中心。 CTN 还将受益于招募两名终身教职、中高级、受资助的研究人员，他们也将成为项目 PI 的导师。此外，在奖项有效期内还将招募另外三名初级教师，以增加研究人员的临界数量。其他潜在的未来 PI 将通过试点研究奖励计划招募。在奖励期结束时，机构对这项工作的重大承诺将转化为对该中心的独立外部支持（P50 奖励）。 CTN 主任拥有大型开发计划、计划项目拨款方面的经验，并已获得联邦资助 20 多年。我们将建立一个核心设施和一个实验核心，以提供一种有效的手段，确保经过培训的专业人员充分利用、维护和操作复杂而昂贵的仪器。我们将确保项目 PI 能够获得最先进的服务和设施（通过每年购买新设备），为 UAMS 的转化神经科学研究工作提供基本基础。