Youth Drug Use, Violence Exposure, and Physiology

青少年吸毒、暴力暴露和生理学

• 批准号: 7254827
• 负责人: WENDY L KLIEWER
• 金额: $ 16.57万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7254827
• 关键词: Adolescent; Area; Arousal; Arts; Attention; Biological Markers; Blood Pressure; Clinical; Communities; Consultations; Dace; Data; Data Collection; Dependence; Drug abuse; Drug usage; Emotional; Exposure to; Family; Family history of; Female; Gender; Hydrocortisone; Hypothalamic structure; Interview; K-Series Research Career Programs; Laboratories; Link; Marijuana; Measures; Mentors; Michigan; Mosses; National Institute of Drug Abuse; Parenting behavior; Pattern; Pennsylvania; Pharmaceutical Preparations; Physiological; Physiology; Pituitary-Adrenal System; Property; Prospective Studies; Recruitment Activity; Research; Research Personnel; Research Training; Risk; Salivary; Sampling; Scientist; Series; Sex Characteristics; Sleep disturbances; Statistical Methods; Statistical Models; Stress; Structural Models; Techniques; Training; Training Support; Universities; Violence; Virginia; Work; Youth; adolescent drug use; base; biological adaptation to stress; coping; design; drug abuser; male; metropolitan; prospective; psychologic; response; statistical center; stressor

DESCRIPTION (provided by applicant): A five-year NIDA Mentored Scientist Career Development Award (K01) is requested to support training and research intended to extend the candidate's previous work in violence exposure and coping in adolescents to the drug abuse and physiological stress responses to violence. In the long term, the candidate wishes to understand linkages between community violence exposure, physiological stress responses, and drug abuse, with attention to gender differences and familial contributions, using state of the art measures of stress response and state of the art statistical models. Formal training will be provided by bi-monthly meetings with the candidate's mentors, Drs. Dace Svikis and Albert Farrell, and by regular consultation with the three external consultants, Drs. Ken Winters, Howard Moss, and Gary Wand. In addition, she will attend two statistical courses offered by the Center for Statistical Consultation at the University of Michigan, one course in longitudinal analyses offered by the University of Virginia, and a training course in using biological markers in research offered by The Pennsylvania State University. The candidate's research is intended to answer a series of questions about associations between community violence exposure, stress responses produced by the Hypothalamus- Pituitary-Adrenal (HPA) axis, and drug use initiation and abuse through analysis of existing data and collection of new data. A community-based, longitudinal, prospective study that incorporates face-toface interviews and laboratory-based physiological assessments will be undertaken to achieve this aim. Two hundred fifty male and female early (10-11 yrs) and middle (14-15 yrs) adolescents from high violence areas in the Richmond, VA metropolitan area will be recruited. A variety of statistical methods and multivariate structural modeling techniques will be used to estimate relations between violence exposure, physiological stress responses, and drug use and abuse, and to examine whether these associations are moderated by gender or familial factors.

描述（由申请人提供）： NIDA五年的指导科学家职业发展奖（K01）被要求支持培训和研究，旨在扩大候选人以前在暴力暴露和应对青少年对暴力毒品滥用和生理压力反应中的工作。从长远来看，候选人希望使用压力反应和最先进的统计模型的状态测量的状态来了解社区暴力暴露，生理压力反应和药物滥用之间的联系，并关注性别差异和家族贡献。双月一次会议将与候选人的导师博士举行。 Dace Svikis和Albert Farrell，并通过与三位外部顾问Drs进行定期咨询。肯·温特斯，霍华德·莫斯和加里·沃德。此外，她将参加密歇根大学统计咨询中心提供的两项统计课程，弗吉尼亚大学提供的纵向分析课程，以及宾夕法尼亚州立大学提供的研究中使用生物标记的培训课程。候选人的研究旨在回答有关社区暴力暴露之间的关联，下丘脑 - 垂体 - 肾上腺（HPA）轴产生的压力反应之间的一系列问题，以及通过分析现有数据和收集新数据的毒品使用和滥用。将进行一项基于社区的纵向，前瞻性研究，结合面对面访谈和基于实验室的生理评估，以实现这一目标。将招募来自弗吉尼亚州里士满的高暴力地区的250名男性和女性（10-11岁）和中间（14 - 15年）的青少年。多种统计方法和多元结构建模技术将用于估计暴力暴露，生理压力反应以及药物使用和滥用之间的关系，并检查这些关联是否由性别或家庭因素调节。

项目成果

THE ROLE OF NEIGHBORHOOD COLLECTIVE EFFICACY AND FEAR OF CRIME IN SOCIALIZATION OF COPING WITH VIOLENCE IN LOW-INCOME COMMUNITIES.

• DOI: 10.1002/jcop.21573
• 发表时间: 2013-11
• 期刊: Journal of community psychology
• 影响因子: 2.3
• 作者: Kilewer W

Do Parent-Adolescent Discrepancies Predict Deviant Peer Affiliation and Subsequent Substance Use?

• DOI: 10.1007/s10964-018-0879-5
• 发表时间: 2018-12-01
• 期刊: JOURNAL OF YOUTH AND ADOLESCENCE
• 影响因子: 4.9
• 作者: Kliewer, Wendy;Sosnowski, David W.;Wright, Anna W.
• 通讯作者: Wright, Anna W.

Community violence exposure, coping, and problematic alcohol and drug use among urban, female caregivers: A prospective study.

城市女性护理人员的社区暴力暴露、应对以及酗酒和吸毒问题：一项前瞻性研究。

• DOI: 10.1016/j.paid.2013.03.020
• 发表时间: 2013
• 期刊: Personality and individual differences
• 影响因子: 4.3
• 作者: Kliewer,Wendy;Zaharakis,Nikola
• 通讯作者: Zaharakis,Nikola

What Do Urban Black Mothers Tell Their Adolescents About Alcohol And Other Drugs?

关于酒精和其他毒品，城市黑人母亲会告诉她们的青少年什么？

• DOI: 10.1111/jora.12094
• 发表时间: 2015
• 期刊: Journal of research on adolescence : the official journal of the Society for Research on Adolescence
• 作者: Zaharakis,NikolaM;Taylor,KatherineA;Kliewer,Wendy
• 通讯作者: Kliewer,Wendy

Maternal and Family Correlates of Intrinsic Religiosity Profiles Among Low-Income Urban African American Adolescents.

低收入城市非裔美国青少年内在宗教信仰的母亲和家庭相关性。

• DOI: 10.1007/s10964-019-01095-y
• 发表时间: 2020
• 期刊: Journal of youth and adolescence
• 影响因子: 4.9
• 作者: Kliewer,Wendy;Washington-Nortey,Melissa;SalifuYendork,Joana;Sosnowski,DavidW;Wright,AnnaW;McGuire,Kristina
• 通讯作者: McGuire,Kristina