Developing and Improving Institutional Animal Resources

开发和改善机构动物资源

• 批准号: 6906095
• 负责人: Lauretta W. Gerrity
• 金额: $ 65万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-10 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6906095
• 关键词: animal care; animal colony; biohazard control; biomedical equipment purchase; biomedical equipment safety; biomedical facility; building /facility design /renovation; laboratory mouse; occupational health /safety; veterinary medicine

DESCRIPTION (provided by applicant): This proposal will contribute to the achievement of our mission of providing and maintaining consistently high quality, healthy animals for UAB research, testing and teaching programs, assuring care of animals consistent with the standards of the Guide for the Care and Use of Laboratory Animals, and providing a safe and healthy workplace for personnel who use or care for animals. Two of the autoclaves and the automatic bedding dispenser will be used in our second oldest facilities, which houses over 25% of the mouse populations on campus and support the animal research activities of more than 40 PHS-funded investigators. The third autoclave will facilitiate decontamination of equipment used in a separate, small containment facility. Demand for this facility for Animal Biosafety Level 2 and 3 studies is increasing. The ventilated cages systems will allow us to improve animal and personnel protection while more efficiently accomodating the growing population of mice. The equipment for which support is being requested also will help us make improvements suggested by AAALAC International, correct deficiencies identified by our Institutional Animal Care and Use Committee, and prepare for the anticipated increase in the use of hazardous agents in response to the biodefense research initiative.

描述（由申请人提供）： 该提案将有助于实现我们的使命，即为 UAB 研究、测试和教学项目提供和维持始终如一的高质量、健康动物，确保动物护理符合《实验动物护理和使用指南》的标准，以及为使用或照顾动物的人员提供安全健康的工作场所。其中两台高压灭菌器和自动垫料分配器将用于我们第二古老的设施，该设施容纳了校园内超过 25% 的小鼠种群，并支持 40 多名 PHS 资助的研究人员的动物研究活动。第三个高压灭菌器将有助于对单独的小型安全壳设施中使用的设备进行净化。对该设施进行 2 级和 3 级动物生物安全研究的需求正在增加。通风笼系统将使我们能够改善动物和人员的保护，同时更有效地容纳不断增长的小鼠数量。请求支持的设备还将帮助我们做出 AAALAC International 建议的改进，纠正我们机构动物护理和使用委员会发现的缺陷，并为响应生物防御研究计划而预计危险制剂的使用增加做好准备。