Neonatal Sucking Organization After Epidural Analgesia

硬膜外镇痛后新生儿吸吮组织

基本信息

批准号：
7337328
负责人：
ALEECA F BELL
金额：
$ 3.54万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-01-16 至 2009-08-15
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7337328
关键词：
Absence of pain sensation Acute Analgesics Animal Model Attenuated Behavioral Birth Birth Rate Breast Feeding Comparative Study Development Devices Disruption Endocrine Epidural Analgesia Exposure to Glucocorticoids Goals Healthy People 2010 Hour Hydrocortisone Incidence Infant Infant Behavior Intramuscular Learning Life Link Measures Mothers Motor Neonatal Numbers Oral Outcome Measure Pain Pain management Perception Perinatal Exposure Personal Satisfaction Pharmaceutical Preparations Physiological Placenta Process Publishing Randomized Range Rate Reporting Research Rewards Salivary Sensory Stress Structure of umbilical artery System Systems Biology United States Urban Hospitals Vaginal delivery procedure Week acute stress alertness behavior measurement biological adaptation to stress critical developmental period dosage experience feeding fetal innovation instrument maternal stress neonate neurobehavioral prenatal stress pressure sucking

项目摘要

The primary aim of this two group comparative study is to examine the relationship between fetal exposure to maternal epidural analgesia during labor and measures of neonatal neurobehavioral organization (behavioral state and sucking organization) in the initial feeding at one hour post birth. The associated effects of epiduralanalgesia on sucking organization have not been previously measured. The secondary aim is to examine the relationship between maternaland fetal acute stress responses (cortisol) during labor, and neonatal behavioral state and sucking organization. This research is innovative in exploring whether an attenuated fetal stress response during the criticalperiodof rapidadaptation after birth is a vulnerable link in the initial development of sucking organization afterbirth. These findings will beaninitial step in examining the mechanisms, and perturbations, of early neonatal neurobehavioral organization. Any disruption in the development of neonatal neurobehavioral organization has the potential to alter mother-infant interaction, and the establishment of successfulbreastfeeding, especially in vulnerable dyads.

这两个小组比较研究的主要目的是检查胎儿暴露之间的关系在劳动期间和新生神经组织的措施中进行母体硬膜外镇痛（行为状态和吮吸组织）在出生后一小时的初始喂养中。关联硬膜外术对吮吸组织的影响先前尚未测量。次要目的是检查分娩过程中母体和胎儿急性应激反应（皮质醇）之间的关系，以及新生儿的行为状态和吮吸组织。这项研究具有创新的探索在出生后重生过程中快速添加期间的胎儿压力反应是脆弱的联系吮吸组织的初步发展。这些发现将在检查早期新生儿神经行为组织的机制和扰动。任何中断新生儿神经行为组织的发展有可能改变母亲互动，并建立成功的胸骨喂养，尤其是在脆弱的二元组中。