FASEB Summer Research Conference "Trace Element Metabolism: Basic and Applied Res

FASEB 夏季研究会议“微量元素代谢：基础与应用研究

• 批准号: 7484010
• 负责人: Dennis J Thiele
• 金额: $ 1.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7484010
• 关键词: Agriculture; Animal Model; Area; Biological Process; Biology; Biomedical Research; Boron; Collaborations; Colorado; Copper; Diagnosis; Disabled Persons; Discipline; Equilibrium; Funding; Genetic; Goals; Growth and Development function; Health; Homeostasis; Human; Investigation; Iron; Knowledge; Laboratories; Medicine; Metabolism; Minority; Neck; Numbers; Oral; Organism; Play; Postdoctoral Fellow; Research; Research Personnel; Role; Science; Scientific Advances and Accomplishments; Scientist; Selenium; Series; Speed; Students; Trace Elements; Training; Woman; Zinc; catalyst; human disease; nutrition; posters; sensor; symposium

DESCRIPTION (provided by applicant): This application is for partial support of a FASEB Summer Research Conference on "Trace Element Metabolism: From Model Organisms to Humans", to be held at Snowmass, Colorado June 15-20, 2008. Given the importance of trace elements in global human nutrition and in human disease and the important advances in this field of research, we anticipate holding at least two additional iterations of this meeting in 2010 and 2012. Trace elements are of vital importance in medicine, agriculture and the inter-relationship between agriculture and human health. This proposed FASEB Summer Research Conference will focus on topics covering the most exciting and important breakthroughs in understanding both basic and applied aspects of trace element homeostasis and metabolism. In this meeting we will largely focus on the trace elements iron (Fe), copper (Cu), zinc (Zn), selenium (Se) and boron (B), as they constitute a group of trace elements that serve critical roles in biology. As is evidenced by the dramatic increase in the number of newly discovered biological processes in which trace elements play pivotal roles as catalysts, sensors, regulatory molecules and structural co-factors, this field of investigation is expanding at an extremely rapid pace. Given the importance of the field and its potential to continue to make ground-breaking discoveries of broad fundamental importance and the large scientific demand for opportunities to communicate and interact, the topic of this meeting is both exciting and timely. The specific aims for this proposal are to (1) organize and support a meeting on the latest scientific advances in the research area of trace element homeostasis and metabolism (2) promote interactions between scientists and clinician/scientists and trainees to share new discoveries in the field of trace element metabolism as it relates to normal growth, development and nutrition and to enhance training and new collaborations that will move the field forward and (3) to directly involve newly independent scientists and trainees including graduate students and postdoctoral fellows, women, minorities and the disabled in the conference. Our goal is to provide access to cutting edge science via oral and poster presentations, to allow opportunities for interactions between trainees and established investigators and other colleagues and to encourage and support long- term and significant advances in this important area of biomedical research. Proposal Narrative Description Trace elements such as copper and iron are essential for normal human growth and development, but are toxic when accumulated to high levels. This application is for partial support of a research conference to serve as a forum to advance our understanding of how organisms properly balance trace element usage and to utilize this knowledge to facilitate the diagnosis and treatment of human diseases of trace element metabolism caused by genetic, environmental and dietary mechanisms.

描述（由申请人提供）： 此应用是为了部分支持faseb夏季研究会议“痕量元素代谢：从模型有机体到人类”，将在2008年6月15日至20日在科罗拉多州的雪摩斯举行。鉴于痕量因素在全球人类营养和人类营养以及人类疾病中的重要性以及在这种研究领域的重要进步，至少有两种培养在这项研究中，我们在2010年和2010年均具有范围。农业与人类健康之间的关系。拟议的FASEB夏季研究会议将重点介绍涵盖痕量元素稳态和代谢的基本和应用方面最令人兴奋和最重要的突破的主题。在这次会议上，我们将主要关注铁（Fe），铜（Cu），锌（Zn），硒（SE）和硼（B）的痕量要素，因为它们构成了一组痕量元素，它们在生物学中起着关键作用。正如新发现的生物学过程数量的急剧增加所证明的那样，痕量元素随着催化剂，传感器，调节分子和结构共同因素的关键作用而发挥关键作用，这种研究领域正在以极快的速度扩展。鉴于该领域的重要性及其潜力继续使人们对广泛重要性的开创性发现以及对交流和互动机会的巨大科学需求，这次会议的主题既令人兴奋又及时。该提案的具体目的是（1）组织和支持有关痕量要素稳态和代谢研究领域的最新科学进步的会议（2）促进科学家与临床医生/科学家和学员之间的互动，以在痕量元素的领域中共享新的发现，以与新的培训和新的培训相关，以使其与正常的成长和营养相关，以使其与新的培训有关，从而使（直接发展）向前培训，并推动（发展），以推动培训和营养，并促进了（促进）的培训和营养，并将其与营养，营养和营养发展，该领域的培训和培训主义者的领域相关。以及包括研究生和博士后研究员，妇女，少数民族以及会议中的残疾人在内的学员。我们的目标是通过口头和海报演示提供进入尖端科学的访问权限，以便为受训者与已成熟的调查员和其他同事之间的互动机会提供机会，并鼓励和支持这一重要领域的生物医学研究领域的长期和重大进步。建议叙事描述铜和铁等微量元素对于正常的人类生长和发育至关重要，但在积累高水平时具有毒性。该应用是为了部分支持研究会议的部分支持，作为论坛，以促进我们对生物如何正确平衡痕量元素使用的理解，并利用这些知识来促进遗传，环境和饮食机制引起的痕量元素代谢的人类疾病的诊断和治疗。