EMBRYOLOGY

胚胎学

基本信息

批准号：
7435209
负责人：
Lee A. Niswander
金额：
$ 21.61万
依托单位：
MARINE BIOLOGICAL LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-06-01 至 2012-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7435209
关键词：
Address American Amphibia Animals Arts Behavior Biological Biological Models Caenorhabditis elegans Cell Differentiation process Cell fusion Chalk Class Climate Controls Cnidaria Collection Commit Communities Complex Computers Computing Methodologies Crustacea Ctenophora Daily Depth Development Developmental Biology Drosophila genus Educational process of instructing Educational workshop Electron Microscopy Embryo Embryology Environment Equipment Evolution Exercise Exposure to Faculty Gene Expression Regulation Generations Germ Layers Goals Homeobox Genes Image Image Analysis Imaging technology In Situ Hybridization Individual Injection of therapeutic agent Insecta International Invertebrates Knowledge Laboratories Laboratory Research Lasers Lateral Lead Leadership Learning Libraries Maintenance Mammals Marines Microinjections Micromanipulation Microscopy Microsurgery Modernization Molecular Molecular Genetics Mus Nematoda Numbers Pattern Formation Phylogeny Play Positioning Attribute Principal Investigator Purpose Radiation Rana Range Recording of previous events Research Research Institute Research Personnel Research Project Grants Role Safety Sea Urchins Senior Scientist Series Students System Techniques Technology Temperature Testing Time Training Transcriptional Regulation Universities Update Week Wood material Work Zebrafish animal facility ascidian base biological research career comparative concept design experience hemichordate improved in vivo instructor lecturer lectures medical schools member pre-doctoral programs research study response tissue culture

项目摘要

DESCRIPTION (provided by applicant): For over 113 years, the Marine Biological Laboratory has offered the Embryology Course, which has played an important role in the training of American developmental biologists. The course trains pre- and postdoctoral students for research careers in developmental biology in a unique physical and intellectual environment, not duplicated elsewhere in the nation. The Embryology Course consists of a series of formal lectures, informal seminars, extended discussions, and intensive laboratory research experience delivered over a six-week period in the summer. Course students are selected who are committed to teaching and research careers in the field of developmental biology, and are chosen from an international applicant pool. Traditionally, a number of the students from each year's class later move into positions of leadership in the international developmental biology research community. The teaching faculty members are senior scientists in the field, some of whom serve as instructors and lead research modules in the course, and others will give lectures and lead discussion on individual topics. The course consists of three modules, each of which is about two weeks long. Each module is staffed by an average of three to four resident instructors plus a comparable number of outside lecturers. The themes of the modules change from year to year as important developments in the field change. The course introduces students to a large number of terrestrial and marine embryos including C. elegans, Drosophila, ascidians, sea urchins, amphibians, zebrafish, chick, and mouse. Approaches include current molecular biological technologies, embryonic manipulation, microinjection and micromanipulation, microscopy and computer enhanced imaging technologies, and a number of immunochemical and in situ hybridization approaches. Students are challenged to formulate and test hypotheses in a well-equipped research environment and under the guidance of experienced research faculty and assistants. In support of the course, the Marine Biological Library provides a unique learning environment, laboratory and support facilities, an animal collection facility, and an excellent research library.

描述（由申请人提供）： 113年来，海洋生物实验室提供胚胎学课程，在美国发育生物学家的培训中发挥了重要作用。该课程在独特的物理和智力环境中培训博士前和博士后学生从事发育生物学的研究工作，该环境在全国其他地方没有重复。胚胎学课程包括一系列正式讲座、非正式研讨会、扩展讨论以及夏季为期六周的密集实验室研究经验。课程学生是从国际申请者中挑选出来的，致力于发育生物学领域的教学和研究职业。传统上，每年班级的一些学生后来会进入国际发育生物学研究界的领导职位。教学教师都是该领域的资深科学家，其中一些人担任课程的讲师并领导研究模块，另一些人将就个别主题进行讲座和领导讨论。该课程由三个模块组成，每个模块持续约两周。每个模块平均配备三到四名常驻讲师以及相当数量的外部讲师。随着该领域重要发展的变化，模块的主题每年都会发生变化。该课程向学生介绍大量的陆地和海洋胚胎，包括线虫、果蝇、海鞘、海胆、两栖动物、斑马鱼、小鸡和小鼠。方法包括当前的分子生物学技术、胚胎操作、显微注射和显微操作、显微镜和计算机增强成像技术以及许多免疫化学和原位杂交方法。学生面临的挑战是在设备齐全的研究环境中并在经验丰富的研究教师和助理的指导下制定和测试假设。为了支持该课程，海洋生物图书馆提供了独特的学习环境、实验室和支持设施、动物收藏设施以及优秀的研究图书馆。