PREPARATION, DERIVATIZATION &: NANOSTRUCTURED MATERIALS

制备、衍生化

• 批准号: 7355190
• 负责人: Karen L. Wooley
• 金额: $ 0.12万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7355190
• 关键词: PREPARATION; DERIVATIZATION; NANOSTRUCTURED; MATERIALS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The self-assembly and covalent stabilization of amphiphilic block copolymers is being developed as a methodology for the preparation of robust nanostructured materials of well-defined structure, composition, and size, which are designed for specific materials properties and to exhibit selective biological interactions. MALDI-TOF has been a critical characterization tool for the characterization of the amphiphilic block copolymers. Mass spectrometric analysis has also played a significant role in the characterization of molecular components, e.g. antibiotics, peptides, sugars, etc., used to surface decorate the nanostructures.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。两亲性嵌段共聚物的自组装和共价稳定正在被开发为一种制备具有明确结构、组成和尺寸的坚固纳米结构材料的方法，这些材料是针对特定材料特性并表现出选择性生物相互作用而设计的。 MALDI-TOF 一直是表征两亲性嵌段共聚物的关键表征工具。质谱分析在分子成分的表征中也发挥了重要作用，例如分子成分。抗生素、肽、糖等，用于纳米结构的表面装饰。