Integrative Cognitive-Affective Therapy for Bulimia Nervosa

神经性贪食症的认知情感综合疗法

• 批准号: 7496016
• 负责人: Stephen Arthur Wonderlich
• 金额: $ 18.82万
• 依托单位: SANFORD RESEARCH NORTH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-13 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7496016
• 关键词: Abstinence; Adherence; Affective; Anxiety; Beck depression inventory; Behavior; Behavioral; Binge Eating; Bulimia; Chronic; Client satisfaction; Clinical; Cognitive; Cognitive Therapy; Competence; Complex; Data; Drops; Eating Disorders; Emotions; Equipment and supply inventories; Frequencies; Funding; Grant; Impairment; Individual; Intervention; Manuals; Measures; Mediation; Mental Depression; Mental disorders; Modeling; Motivation; Numbers; Outcome Measure; Patients; Pattern; Personal Digital Assistant; Phase; Procedures; Psychopathology; Randomized Controlled Trials; Range; Rate; Relapse; Symptoms; Techniques; Testing; Week; base; digital; improved; medical complication; psychologic; purge; response; satisfaction; self esteem; social; theories; therapy development; trait; trial comparing

DESCRIPTION (provided by applicant): Bulimia nervosa (BN) is a serious and often chronic psychiatric disorder with high rates of medical complications, social impairment and comorbid psychopathology. Cognitive behavioral therapy (CBT) has been shown to be an efficacious approach to the treatment of BN with substantial reductions in core binge eating and compensatory behaviors, as well as psychological impairments. However, in spite of its demonstrated efficacy, 50-70% of bulimic individuals remain symptomatic following treatment with CBT, a significant number drop out of treatment, and relapse rates are substantial. The need for new psychological treatments for BN that can improve the overall response to treatment is high. Integrative cognitive-affective therapy (ICAT) is a new, manual-based, psychological approach to the treatment of BN. ICAT incorporates both conceptual and clinical techniques from existing theories of motivation, emotion, interpersonal functioning, and behavioral change interventions. ICAT is based on a conceptual model of BN that includes several core constructs such as self-discrepancy, affective states, interpersonal patterns, and self-directed style. ICAT includes a clinician manual, patient workbook, and personal digital assistant based treatment modules, all of which are offered in a 20-session, 16-week format. Pilot data testing the model underlying ICAT are promising and suggest that several of the core constructs are significantly associated with BN. Furthermore, two waves of pilot testing indicate that ICAT is feasible to administer and is able to reduce bulimic symptomatology in a relatively short timeframe. ICAT appears to be a promising approach to the treatment of BN and we are requesting funding in this application to refine treatment manuals, develop assessment procedures, and conduct a small randomized controlled trial comparing ICAT to CBT.

描述（由申请人提供）：神经性贪食症（BN）是一种严重的慢性精神病，医疗并发症，社会障碍和合并症的精神病理学率很高。认知行为疗法（CBT）已被证明是对BN治疗的一种有效方法，其核心暴饮暴食和补偿性行为以及心理障碍大幅减少。然而，尽管它表现出了功效，但在用CBT治疗后，有50-70％的贪食症个体仍然有症状，大量退出治疗，复发率很高。对BN的新心理治疗的需求可以改善对治疗的总体反应。综合认知影响疗法（ICAT）是一种基于手动的，心理的心理学方法。 ICAT从现有的动机，情感，人际功能和行为改变干预措施的概念和临床技术中都结合了概念和临床技术。 ICAT基于BN的概念模型，该模型包括几种核心构造，例如自我证明，情感状态，人际模式和自我指导的风格。 ICAT包括临床医生手册，患者工作簿和个人数字助理治疗模块，所有这些模块均以20期，16周的形式提供。试点数据测试ICAT的模型很有希望，并表明几种核心结构与BN显着相关。此外，两次试验测试表明，ICAT可行可行，并且能够在相对较短的时间范围内减少大胆的症状。 ICAT似乎是BN治疗的一种有前途的方法，我们要求在本申请中提供资金，以完善治疗手册，制定评估程序并进行一项将ICAT与CBT进行比较的小型随机对照试验。