BRAIN FUNCTION STUDY WITH GENERALIZED ANXIETY DISORDER (GAD) PATIENTS USING MRS

使用 MRS 对广泛性焦虑症 (GAD) 患者的脑功能进行研究

• 批准号: 7380531
• 负责人: JACK M. GORMAN
• 金额: $ 1.72万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-17 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7380531
• 关键词: anxiety; anxiety disorders; attention; brain; magnetism; mood disorders; neurobiology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. For many years it was incorrectly assumed that generalized anxiety disorder (GAD) is uncommon, that most patients with GAD are actually depressed, and that GAD patients are only mildly ill. Although it is now clear that none of these assumptions is correct, biological investigators have been slow to turn their attention to GAD. This leaves a major gap in our knowledge about anxiety disorders, because GAD often begins early in life and appears to predispose to other psychiatric illnesses. The characteristic features of GAD - constant worry, apprehension, and tension - are fundamental to most of the other anxiety and mood disorders. Hence, understanding the fundamental neurobiology of GAD appears to be of importance. The purpose of this study is to investigate brain function using magnetic resonance spectroscopy (MRS/MRI).

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。多年来，人们错误地认为广泛性焦虑症 (GAD) 并不常见，大多数 GAD 患者实际上患有抑郁症，而且 GAD 患者只是病情较轻。尽管现在很清楚这些假设都不正确，但生物学研究人员却迟迟没有将注意力转向广泛性焦虑症。这使得我们对焦虑症的了解存在重大空白，因为广泛性焦虑症通常在生命早期开始，并且似乎容易患其他精神疾病。广泛性焦虑症的典型特征——持续的担忧、忧虑和紧张——是大多数其他焦虑和情绪障碍的基础。因此，了解广泛性焦虑症的基本神经生物学似乎很重要。 本研究的目的是利用磁共振波谱 (MRS/MRI) 研究大脑功能。