IMMUNOGENICITY OF LIVE ATTENUATED VARICELLA VACCINE HIV INFECTED CHILDREN

水痘减毒活疫苗对 HIV 感染儿童的免疫原性

• 批准号: 7379533
• 负责人: Stephen I. Pelton
• 金额: $ 0.11万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7379533
• 关键词: IMMUNOGENICITY; LIVE; ATTENUATED; VARICELLA; VACCINE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Varicella-Zoster virus infection is usually benign in normal children. It can be devastating in HIV infected children. HIV infected children are subject to repeated injections of VZIG. This study will test the ability of children with early and mild HIV infection to respond to the vaccine and measure the safety and duration of immunity achieved in immunized children.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。水痘带状疱疹病毒感染在正常儿童中通常是良性的。对于感染艾滋病毒的儿童来说，这可能是毁灭性的。 HIV 感染儿童需要重复注射 VZIG。这项研究将测试早期和轻度艾滋病毒感染儿童对疫苗的反应能力，并衡量免疫儿童获得免疫力的安全性和持续时间。