MECHANISMS UNDERLYING ENHANCED ALVEOLAR MACROPHAGE ACCESSORY FUNCTION IN HIV

HIV 肺泡巨噬细胞辅助功能增强的机制

• 批准号: 7379043
• 负责人: Homer L Twigg
• 金额: $ 0.44万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7379043
• 关键词: MECHANISMS; UNDERLYING; ENHANCED; ALVEOLAR; MACROPHAGE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The current study is designed to investigate mechanisms underlying this enhancement looking at factors and direct cell to cell interactions as potential mediators. The ability of resting and activated AM to release certain lymphoproliferative enhancing cytokines will be measured.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。当前的研究旨在研究这种增强的基础机制，从而将因子并将细胞引导到细胞相互作用作为潜在的介体。将测量静止和激活AM释放某些淋巴增强性增强细胞因子的能力。