RANDOMIZED, MULTICENTER TACROLIMUS WITH STEROID VS STEROID FREE (SNS-01)

随机、多中心他克莫司含类固醇与不含类固醇 (SNS-01)

• 批准号: 7380757
• 负责人: WILLIAM E. HARMON
• 金额: $ 1.99万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7380757
• 关键词: RANDOMIZED; MULTICENTER; TACROLIMUS; STEROID; VS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The study objective is to compare the safety and efficacy of a traditional steroid based-protocol (Prograf, MMF, steroids and standard daclizumab induction until the second month post-transplant) to a steroid-free protocol (Prograf, MMF and daclizumab induction until the sixth month post-transplant). Precise endpoint definition and power considerations are described in the statistical section of this protocol.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。研究目的是比较传统类固醇方案（Prograf、MMF、类固醇和标准达珠单抗诱导直至移植后第二个月）与无类固醇方案（Prograf、MMF 和达珠单抗诱导直至移植后第二个月）的安全性和有效性。移植后第六个月）。本协议的统计部分描述了精确的端点定义和功率注意事项。