Prevention of Obesity at Universities:A Randomized Trial

大学预防肥胖：随机试验

• 批准号: 7011276
• 负责人: MICHAEL R LOWE
• 金额: $ 48.9万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-20 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7011276
• 关键词: adipose tissue; adolescence (12-20); behavior modification; behavioral /social science research tag; body physical activity; clinical research; clinical trials; depression; disease /disorder onset; disease /disorder prevention /control; eating disorders; female; human subject; longitudinal human study; motivation; nutrition education; obesity; patient oriented research; social psychology; university student

DESCRIPTION (provided by applicant): Because obesity is reaching epidemic proportions, results in marked morbidity and mortality, and is resistant to treatment, it is vital to develop prevention programs for this public health problem. Unfortunately, most universal prevention programs have not reduced the risk for future weight gain. Thus, we decided to target a subset of individuals-female restrained eaters entering college-who might be uniquely motivated to make lasting changes to their diet and activity level that would decrease their risk for obesity onset. In the proposed College Weight Control Program (CWCP), adolescent females are taught methods to reduce the portion size and energy density of their food choices and to increase their physical activity to prevent weight gain. The intervention utilizes persuasion principles from social and clinical psychology (e.g., strategic self-presentation, motivational interviewing) to increase the likelihood that participants will make lasting behavioral changes. The 5-session intervention is brief relative to extant programs, which should facilitate dissemination. A preliminary trial (N = 188) found that participants who completed an earlier version of this program were at significantly lower risk for obesity onset (3%) over a 2-year follow-up relative to assessment-only controls (11%) and showed greater improvements in healthy eating and activity level. This program also reduced eating disorder symptoms and negative affect, which is important because these disturbances are marked by functional impairment and adverse outcomes. Accordingly, we propose to conduct a large-scale randomized trial of an enhanced version of this targeted obesity prevention program at 2 local universities. We will randomly assign 350 female restrained eaters (aged 17-19) during their freshman year to the control or experimental group and follow them for 2 years. We will test whether the CWCP, relative to a no-treatment control condition, results in (1) decreased risk for gain of body fat and onset of obesity, (2) improvements in energy intake and the nutritional composition of the diet, (3) increases in physical activity, (4) decreased eating disorder and depressive symptoms, and (5) reduced levels of several medical risk factors.

描述（由申请人提供）：由于肥胖已达到流行病的程度，导致显着的发病率和死亡率，并且对治疗具有抵抗力，因此针对这一公共卫生问题制定预防计划至关重要。不幸的是，大多数普遍的预防计划并没有降低未来体重增加的风险。因此，我们决定针对一部分人——进入大学的女性节食者——她们可能有独特的动机对自己的饮食和活动水平进行持久的改变，以降低肥胖发生的风险。在拟议的大学体重控制计划（CWCP）中，青春期女性学习如何减少食物选择的份量和能量密度，并增加体力活动以防止体重增加。该干预措施利用社会和临床心理学的说服原则（例如，策略性自我展示、动机性访谈）来增加参与者做出持久行为改变的可能性。与现有计划相比，为期 5 次的干预措施很简短，这应该有助于传播。一项初步试验 (N = 188) 发现，与仅进行评估的对照组 (11%) 相比，完成该计划早期版本的参与者在 2 年随访中的肥胖风险 (3%) 显着降低，在健康饮食和活动水平方面显示出更大的改善。该计划还减少了饮食失调症状和负面影响，这一点很重要，因为这些障碍的特点是功能障碍和不良后果。因此，我们建议在两所本地大学对这一针对性肥胖预防计划的增强版进行大规模随机试验。我们将 350 名大一期间限制饮食的女性（17-19 岁）随机分配到对照组或实验组，并跟踪她们 2 年。我们将测试 CWCP 相对于无治疗对照条件是否会导致 (1) 降低体脂增加和肥胖发生的风险，(2) 改善能量摄入和饮食的营养成分，(3 ）增加体力活动，（4）减少饮食失调和抑郁症状，以及（5）降低多种医疗风险因素的水平。