BABOON MODEL FOR STUDY OF PRIMATE MATERNAL BEHAVIOR

用于研究灵长类母性行为的狒狒模型

• 批准号: 7349743
• 负责人: Linda Y Brent
• 金额: $ 8.04万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7349743
• 关键词: BABOON; MODEL; STUDY; PRIMATE; MATERNAL

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Maternal behavior in primates is a complex process, involving a number of physiological and life history variables. This study is the first to include behavioral, life history, endocrine, and genetic data from a large number of nonhuman primate subjects in the determination of factors related to maternal behavior. The project will increase our knowledge of the heritable nature of variation in maternal behavior, will characterize mothers with poor maternal qualities, and will provide information useful for selecting females used in breeding programs. This project generates behavioral and hormonal profiles to be used in the development of the baboon as a model of maternal behavior by quantifying mother-infant interactions, determining infant outcome, and measuring hormone levels in a large sample of captive baboons. It will then examine the causes of variation in maternal behavior, including hormonal, experiential, and genetic factors. It is expected that the information resulting from this study will lead to new avenues of research on the mechanisms involved in the regulation of maternal behavior, as will as providing a model for related studies in reproductive endocrinology, colony management and behavioral research.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。灵长类动物中的孕产妇行为是一个复杂的过程，涉及许多生理和生活历史变量。这项研究是第一个在确定与孕产妇行为有关的因素时，包括大量非人类灵长类动物受试者的行为，生活史，内分泌和遗传数据。该项目将提高我们对孕产妇行为变化的可遗传性质的了解，将表征母亲品质差的母亲，并提供对选择育种计划中使用的女性有用的信息。该项目通过量化母亲相互作用，确定婴儿的结果并测量大量圈养狒狒样本中的激素水平来产生用于开发狒狒行为模型的行为和激素谱。然后，它将检查孕产妇行为变化的原因，包括激素，经验和遗传因素。可以预期，这项研究产生的信息将导致有关孕产妇行为调节机制的研究的新途径，这将为生殖内分泌学，殖民地管理和行为研究提供相关研究的模型。