Behavior Intervention on Anxiety in Children with Autism

自闭症儿童焦虑的行为干预

• 批准号: 7232076
• 负责人: Amy Drahota
• 金额: $ 2.99万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7232076
• 关键词: Address; Aftercare; Age; Anxiety; Anxiety Disorders; Autistic Disorder; Behavior Therapy; Child; Clinic; Clinical; Cognitive Therapy; Comorbidity; Condition; Control Groups; Daily; Diagnosis; Experimental Designs; Failure; Fellowship; Heterogeneity; High Prevalence; Impairment; Individual; Intervention; Lead; Life; Literature; Manuals; Measures; Modification; Names; Outcome; Parents; Phase; Psychopharmacology; Randomized; Range; Rate; Research Personnel; Risk; Schools; Self Efficacy; Social Adjustment; Social Functioning; Subgroup; Symptoms; Testing; Voluntary Mutism; Waiting Lists; autism spectrum disorder; daily functioning; design; experience; functional disability; improved; programs; psychosocial; remediation; size; skills; social; social skills; success

DESCRIPTION (provided by applicant): Children with high functioning autism (HFA) are at heightened risk for anxiety disorders when compared with neurotypical children. The high prevalence rate of anxiety disorders in HFA is suggestive of a distinct subgroup of children on the autism spectrum-an "anxious-inhibited" subgroup. Due to complications that comorbid diagnoses can add to the adaptive functioning of children with HFA, and because the psychosocial intervention literature has been marked with few successes, researchers have recommended addressing specific symptoms and prevalent subgroups found among children with HFA. The proposed study is designed to examine the efficacy of a recently modified cognitive behavioral therapy (CBT) program in the remediation of anxiety symptoms in children with HFA. This study will include a pilot phase with 3 children with HFA ranging in age from 7-13 years, allowing further refinement and modification of the CBT manual. Thereafter, 28 children will be randomly assigned to either immediate treatment or waitlist control conditions; children and primary parents will be provided a multimodal CBT intervention in a clinic setting. Children assigned to the waitlist control group will receive the full treatment after 3 months. This experimental design will allow me to test the impact of CBT on children's anxiety and adaptive functioning. Measures of anxiety, social, academic, and daily living skills functioning, as well as treatment acceptability will serve as primary outcomes and will be assessed immediately following intervention and at 3 months post treatment.

描述（由申请人提供）：与神经正常儿童相比，高功能自闭症（HFA）儿童患焦虑症的风险更高。 HFA 中焦虑症的高患病率表明自闭症谱系儿童中存在一个独特的亚组——“焦虑抑制”亚组。由于合并症诊断可能会增加 HFA 儿童的适应功能，并且心理社会干预文献几乎没有取得成功，因此研究人员建议解决 HFA 儿童中发现的特定症状和常见亚组。拟议的研究旨在检验最近修改的认知行为疗法 (CBT) 计划在治疗 HFA 儿童焦虑症状方面的功效。这项研究将包括对 3 名年龄在 7-13 岁之间患有 HFA 的儿童进行试点阶段，以便进一步完善和修改 CBT 手册。此后，28 名儿童将被随机分配到立即治疗或候补控制条件组；儿童和主要父母将在诊所接受多模式 CBT 干预。分配到等候名单对照组的儿童将在 3 个月后接受全面治疗。这个实验设计将使我能够测试 CBT 对儿童焦虑和适应性功能的影响。焦虑、社交、学业和日常生活技能功能以及治疗可接受性的测量将作为主要结果，并将在干预后立即和治疗后 3 个月进行评估。