Decision Aid to Enhance CHD Risk Factor Modification

加强冠心病危险因素修正的决策援助

• 批准号: 7099546
• 负责人: STACEY L SHERIDAN
• 金额: $ 15.74万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7099546
• 关键词: Internet; atherosclerosis; behavioral /social science research tag; behavioral medicine; cardiovascular disorder education; cardiovascular disorder prevention; cardiovascular disorder risk; clinical research; computer assisted instruction; coronary disorder; counseling; decision making; education evaluation /planning; educational resource design /development; focus groups; health behavior; human subject; literature survey; patient care personnel relations; patient oriented research; therapy compliance

DESCRIPTION (provided by applicant): Candidate: Stacey L. Sheridan, MD, MPH, is an Assistant Professor of Medicine at the University of North Carolina. She is board certified in prevention, has training in primary care research, and has developed a knowledge base in risk communication and shared decision-making. She has a special interest in coronary heart disease (CHD) prevention. Career Goals: To become a productive independent investigator who can apply rigorous research methods to study and improve patient-provider decision-making about CHD and patient adherence to CHD risk-reducing medications. Career Development Plans: Dr. Sheridan proposes tutorials, mentored research, and professional development activities to help her develop a clinical research focus in CHD prevention, necessary methodological skills, and skills to excel as an independent investigator. Research Study Aims: (1) To collect formative data from appropriately selected patients (at risk, but without diagnosed CHD or diabetes) to understand patient comprehension of global CHD risk, how patients use CHD risk in decision making, and what factors influence patients to adhere to CHD prevention strategies, (2) to develop and/or refine the components of an intervention to improve decision-making and adherence about CHD risk reducing medications (including a web-based decision aid, a web-based coaching tool, a provider education session, and tailored adherence reminders), (3) to pre-test each component of the intervention using cognitive and usability testing methods, and (4) to perform a feasibility study of the intervention (n=200). Significance: This study is responsive to new guidelines that recommend decision-making based on global CHD risk and targets patients' educational and adherence needs in an evidence and theory-based format. This study will provide preliminary data for a subsequent R-01 application to study whether a robust CHD intervention can be used to improve decision-making and adherence in a multi-site randomized trial. Environment: The general medicine ambulatory care clinic at the University of North Carolina. This clinic has a patient-oriented research lab that is conducting similar studies. Mentorship and Clinical Advice: A team of productive and successful researchers will guide Dr. Sheridan in her research and career development. This team has a strong foundation in clinical epidemiology and special expertise in cardiovascular disease prevention (Drs. Simpson, Heiss, and Pignone), behavioral theory and adherence support (Dr. Rimer), preventive service utilization (Dr. Harris), and developing and testing behavioral interventions in high-risk populations (Dr. Keyserling) (End of abstract).

描述（由申请人提供）： 候选人：Stacey L. Sheridan，医学博士、公共卫生硕士，是北卡罗来纳大学医学助理教授。她获得了预防委员会认证，接受过初级保健研究培训，并开发了风险沟通和共同决策方面的知识库。她对冠心病（CHD）的预防特别感兴趣。职业目标：成为一名富有成效的独立研究者，能够应用严格的研究方法来研究和改善患者提供者关于 CHD 的决策以及患者对降低 CHD 风险的药物的依从性。职业发展计划：Sheridan 博士提出了教程、指导研究和专业发展活动，以帮助她发展 CHD 预防方面的临床研究重点、必要的方法技能以及作为独立研究者的出色技能。研究目的：(1) 从适当选择的患者（有风险，但未诊断出 CHD 或糖尿病）收集形成性数据，以了解患者对总体 CHD 风险的理解、患者如何在决策中使用 CHD 风险以及哪些因素影响患者遵守 CHD 预防策略，(2) 制定和/或完善干预措施的组成部分，以改善决策制定和对降低 CHD 风险的药物的依从性（包括基于网络的决策辅助、基于网络的辅导工具、提供者教育会议，以及定制的遵守提醒），（3）使用认知和可用性测试方法预先测试干预的每个组成部分，以及（4）进行干预的可行性研究（n = 200）。意义：这项研究响应了新的指南，该指南建议根据全球冠心病风险做出决策，并以基于证据和理论的形式针对患者的教育和依从性需求。这项研究将为后续的 R-01 应用提供初步数据，以研究是否可以使用强有力的 CHD 干预来改善多中心随机试验中的决策和依从性。环境：北卡罗来纳大学的普通内科门诊护理诊所。该诊所有一个以患者为中心的研究实验室正在进行类似的研究。指导和临床建议：由富有成效和成功的研究人员组成的团队将指导 Sheridan 博士的研究和职业发展。该团队在临床流行病学方面拥有坚实的基础，并在心血管疾病预防（Simpson、Heiss 和 Pignone 博士）、行为理论和依从性支持（Rimer 博士）、预防性服务利用（Harris 博士）以及开发和应用方面拥有特殊专业知识。测试高危人群的行为干预措施（Keyserling 博士）（摘要结束）。