Conference on Excitatory Amino Acids & Brain Function

兴奋性氨基酸会议

基本信息

批准号：
7237950
负责人：
ROBERT C MALENKA
金额：
$ 4.86万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-06-23 至 2008-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7237950
关键词：
AMPA Receptors Academia Advertisements Advertising Affective Aging Alabama Alzheimer&apos s Disease Amino Acid Transporter Area Aspartate Basic Science Behavior Disorders Behavioral Biology Boston Brain Brain Injuries Businesses CCL7 gene Calcium Career Choice Cell membrane Cell model Charge Chromosome Pairing Clinical Complex Coupling DLG4 gene Data Dendrites Dendritic Spines Development Disabled Persons Discipline Drug Addiction Educational process of instructing Endocytosis Ensure Environment Epilepsy Equilibrium Equipment Evaluation Excitatory Amino Acid Receptors Excitatory Amino Acids Excitatory Synapse Explosion Faculty Fees Food Fostering Foundations Frequencies Funding Future Gene Targeting Genetic Glutamates Goals Government Grant Holly Huntington Disease Immediate-Early Genes Industry Inhibitory Synapse Institutes Institution International Invertebrates Ion Channel Journals Kainic Acid Receptors Knowledge Laboratories Learning Ligand Binding Link Location Long-Term Depression Long-Term Potentiation Mails Massachusetts Mediating Medical Medical center Medicine Membrane Membrane Protein Traffic Memory Mental Health Mentors Methods Minority Minority Groups Mission Molecular Molecular Genetics Mus N-Methyl-D-Aspartate Receptors National Institute of Child Health and Human Development National Institute of Drug Abuse National Institute of Mental Health National Institute on Alcohol Abuse and Alcoholism Nature Neurodegenerative Disorders Neurons Neurosciences Neurotransmitter Receptor New England North America Numbers Parkinson Disease Participant Persons Phosphoric Monoester Hydrolases Phosphorylation Physiology Play Postdoctoral Fellow Postsynaptic Membrane Presynaptic Receptors Principal Investigator Process Prohibit Property Protein Tyrosine Kinase Proteins Proteomics Publications Questionnaires Rasmussen&apos s Syndrome Rate Recording of previous events Regulation Reporting Request for Proposals Research Research Institute Research Personnel Role Running Scaffolding Protein Schedule Schizophrenia Schools Science Scientist Series Services Shapes Signaling Molecule Site Societies Standards of Weights and Measures Stroke Structure Students Synapses Synaptic Cleft Synaptic Receptors Synaptic Transmission Synaptic plasticity Syndrome System Texas Time Title Training and Education Transportation Travel USA Georgia United States United States National Institutes of Health Universities Ursidae Family Utah Vertebral column Vertebrates Vesicle Visual Washington Week Western Asia Georgia Woman Work alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid amino 3 hydroxy 5 methylisoxazole 4 propionate barrel cortex base brain research calmodulin-dependent protein kinase II career college day design discs, large (Drosophila) homolog 2 protein, rat distraction excitotoxicity frontier glutamate receptor interacting protein human RIPK1 protein interest kainate lectures member nervous system development nervous system disorder neurotransmitter release particle posters postsynaptic presynaptic presynaptic density protein 95 programs receptor receptor function research study response retinotectal scientific organization size stargazin success symposium synaptogenesis synaptotagmin therapy development trafficking transmission process vision development

项目摘要

DESCRIPTION (provided by applicant): The third Gordon Research Conference on Excitatory Amino Acids and Brain Function will be held in July 2003 at Mount Holyoke College in South Hadley, Massachusetts. This meeting has established itself as one of the most important forums for discussing progress in this rapidly moving field. The conference will bring together approximately 130 active investigators, post-doctoral fellows and students for discussion of recent advances in the area of excitatory amino acids (EAAs) and brain function. The science discussed will be highly interdisciplinary, encompassing genetic, molecular, cellular, biophysical, structural, and behavioral approaches to understanding brain function. Specific topics which will be covered at the conference include, structure and function of excitatory amino acid (EAA) receptors, genetic approaches to EAA receptor function using invertebrate and vertebrate systems, membrane trafficking of EAA receptors, presynaptic function at excitatory synapses, regulation of dendritic and spine structure, EAAs and neuronal development and synaptic plasticity. The chosen speakers include the major leaders in the field as well as promising young scientists near the beginning of their careers. This proposal requests funds to provide partial support for travel and registration fees for participants from North America and overseas. This conference is timely and important, as it will bring together investigators from many scientific disciplines whose common link is the elucidation of the role of EAAs in brain function. The unique Gordon Conference format, which encourages informal and open discussion among the participants, provides an ideal environment for the development of new ideas/approaches, and initiation of new collaborative efforts, which will help shape the future directions of this critical field. EAAs play important roles in most higher brain function and are relevant to affective and behavioral disorders, mental health and drug addiction as well as brain development and plasticity. EAAs also are involved in several neurological disorders and diseases of aging such as Alzheimer's and Parkinson's, and other neurodegenerative diseases. The conference should be of interest to the missions of several institutes at NIH including NIMH, NINDS, NICHD, NIA, NIDA and NIAAA.

描述（由申请人提供）：第三届戈登兴奋性氨基酸和脑功能研究会议将于 2003 年 7 月在马萨诸塞州南哈德利的曼荷莲学院举行。这次会议已成为讨论这一快速发展领域进展的最重要论坛之一。此次会议将汇集大约 130 名活跃的研究人员、博士后研究员和学生，讨论兴奋性氨基酸 (EAA) 和大脑功能领域的最新进展。所讨论的科学将是高度跨学科的，涵盖遗传、分子、细胞、生物物理、结构和行为方法来理解大脑功能。会议将讨论的具体主题包括兴奋性氨基酸（EAA）受体的结构和功能、利用无脊椎动物和脊椎动物系统实现EAA受体功能的遗传方法、EAA受体的膜运输、兴奋性突触的突触前功能、树突的调节以及脊柱结构、EAA 和神经元发育和突触可塑性。选定的演讲者包括该领域的主要领导者以及职业生涯刚刚开始的有前途的年轻科学家。该提案要求资金为来自北美和海外的参与者提供部分旅行和注册费支持。这次会议是及时而重要的，因为它将汇集来自许多科学学科的研究人员，他们的共同点是阐明 EAA 在大脑功能中的作用。独特的戈登会议形式鼓励参与者之间进行非正式和公开的讨论，为新思想/方法的发展和新合作努力的启动提供了理想的环境，这将有助于塑造这一关键领域的未来方向。 EAA 在大多数高级大脑功能中发挥着重要作用，并且与情感和行为障碍、心理健康和药物成瘾以及大脑发育和可塑性相关。 EAA 还与多种神经系统疾病和衰老疾病有关，例如阿尔茨海默氏症和帕金森氏症以及其他神经退行性疾病。 NIH 的多个机构（包括 NIMH、NINDS、NICHD、NIA、NIDA 和 NIAAA）的使命应该对这次会议感兴趣。