13th Biennial FASEB Summer Conference on Retinoids

第 13 届 FASEB 类维生素A双年度夏季会议

• 批准号: 7114510
• 负责人: DIANNE R SOPRANO
• 金额: $ 2.9万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7114510
• 关键词: biological transport; cell growth regulation; chemical structure function; enzyme activity; immune response; meeting /conference /symposium; neoplasm /cancer; nuclear receptors; nutrition related tag; retinoid binding proteins; retinoids; travel; vitamin metabolism

DESCRIPTION (provided by applicant): This application requests partial support for the 13th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference on Retinoids to be held at Hyatt Grand Champions Resort and Spa in Indian Wells, CA. from June 17-22, 2006. This bi-annual research conference has been very well attended (ranging from 125 to 200 attendees over the past 24 years) and remains the sole major national and international conference that addresses the full spectrum of retinoid biology. Knowledge of the importance of retinoids to a diverse group of biologically and medically important processes has increased very rapidly over the last two decades. Nevertheless, there is much that still needs to be learned regarding retinoid actions in both normal human physiology and pathophysiology. To meet this need for information, there is a great deal of ongoing research activity focused on the retinoids (the NIH CRISP database indicates that there are currently 420 funded NIH grants involving retinoid biology). The 2006 conference will consist of a plenary lecture, platform presentations and poster sessions that will allow for the exchange of new research findings amongst scientific attendees. The main topics to be addressed at the conference include: (1) retinol formation, transport and metabolism; (2) enzymology of synthesis and degradation of retinoic acid; (3) structure and function of RARs and RXRs; (4) retinoids and cancer; (5) retinoids as regulators of cell growth and differentiation; (5) mechanism of action of retinoids during development; (6) retinoids in immune response; (7) physiological actions of retinoids; and (8) novel retinoids in health and disease. The overall goal of the proposed conference on retinoids is to bring together a group of investigators (including senior scientists, mid-career scientists, junior scientists, postdoctoral fellows and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, developmental biologists, vision researchers, cell biologists, immunologists, chemists and clinicians) to present and discuss their newest research findings that share a common focus on the retinoids. This conference will provide a forum for the critical review of recent research and for the development of new research ideas and collaborations. This will stimulate new investigations that in time will provide needed insight into the essential actions of retinoids in preventing disease and maintaining good health.

描述（由申请人提供）： 本申请请求部分支持将于加利福尼亚州印第安维尔斯凯悦大冠军度假村和水疗中心举行的第 13 届美国实验生物学会联合会 (FASEB) 夏季类视黄醇研究会议。 2006 年 6 月 17 日至 22 日举行。这次两年一度的研究会议出席人数众多（过去 24 年中，与会者人数从 125 人到 200 人不等），并且仍然是唯一讨论类视黄醇生物学全谱的主要国内和国际会议。在过去的二十年中，人们对类视黄醇对多种生物学和医学重要过程的重要性的认识迅速增加。然而，关于类视黄醇在正常人体生理学和病理生理学中的作用，仍然有很多东西需要了解。为了满足这种信息需求，目前有大量针对类视黄醇的研究活动正在开展（NIH CRISP 数据库表明，目前有 420 项 NIH 资助项目涉及类视黄醇生物学）。 2006 年的会议将包括全体演讲、平台演示和海报会议，以便科学与会者交流新的研究成果。会议讨论的主要议题包括：（1）视黄醇的形成、运输和代谢； (2)视黄酸合成与降解的酶学研究； (3) RAR和RXR的结构和功能； (4) 类维生素A与癌症； (5)类维生素A作为细胞生长和分化的调节剂； (5)类维生素A在发育过程中的作用机制； (6)类维生素A在免疫反应中的作用； (7)类维生素A的生理作用； (8)新型类视黄醇在健康和疾病中的作用。拟议的类视黄醇会议的总体目标是汇集一群从事不同学科（如生物化学家、分子生物学家、营养科学家）的研究人员（包括高级科学家、职业中期科学家、初级科学家、博士后研究员和研究生） 、癌症研究人员、发育生物学家、视觉研究人员、细胞生物学家、免疫学家、化学家和临床医生）展示并讨论他们共同关注类维生素A的最新研究成果。这次会议将为对近期研究进行批判性审查以及新研究理念和合作的发展提供一个论坛。这将刺激新的研究，及时为类维生素A在预防疾病和保持健康方面的基本作用提供必要的见解。