INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY

国际化学品安全计划

• 批准号: 7237298
• 负责人: Jenny Pronczuk De Garbino
• 金额: $ 60.25万
• 依托单位: WORLD HEALTH ORGANIZATION
• 依托单位国家: 美国
• 财政年份: 1980
• 资助国家: 美国
• 起止时间: 1980-09-26 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7237298
• 关键词: Address; Advisory Committees; African; Agreement; American; Americas; Archives; Arctic Regions; Area; Argentina; Arsenic; Attention; Awareness; Back; Basic Science; Biochemistry and Cellular Biology; Biological Markers; Biological Monitoring; Brazil; Caribbean natives; Caribbean region; Case Study; Chemical Actions; Chemical Exposure; Chemicals; Child; Child Support; Child health care; Childhood Asthma; Climate; Collaborations; Communication; Communities; Community Participation; Complex; Complex Mixtures; Congresses; Consensus; Consultations; Costa Rica; Country; Czech Republic; Data; Data Collection; Depth; Developed Countries; Developing Countries; Development; Economics; Education; Educational workshop; Effectiveness; End Point; Endocrine Disruptors; Ensure; Environment; Environmental Exposure; Environmental Health; Environmental Pollution; Environmental Risk Factor; Epidemiology; Equipment; Etiology; European; Evaluation; Event; Exposure to; Extramural Activities; Fertilization; Food; Fostering; Foundations; Funding; Future; Generations; Generic Drugs; Genes; Genetic; Genetic Polymorphism; Genetic Predisposition to Disease; Geography; Goals; Government; Guidelines; Health; Health Professional; Human; Incidence; Information Dissemination; Institutes; Institution; International; International Aspects; Joints; Judgment; Knowledge; Laboratories; Lead; Leadership; Life; Link; Literature; Longitudinal Studies; Malaysia; Malnutrition; Medical Research; Methodology; Methods; Mexico; Modeling; Molecular Epidemiology; Monitor; Multimedia; Numbers; Organophosphates; Outcome; Pan American Health Organization; Pan Genus; Participant; Peer Review; Peru; Pesticides; Phase; Pilot Projects; Play; Poison; Policies; Population; Population Group; Predisposition; Prevention; Prevention strategy; Principal Investigator; Procedures; Process; Protocols documentation; Public Health; Publications; Quality Control; Research; Research Activity; Research Infrastructure; Research Personnel; Research Priority; Research Project Grants; Resources; Risk; Risk Assessment; Role; Safety; Science; Scientist; Seeds; Series; Societies; Source; South Africa; Southeastern Asia; Staging; Standards of Weights and Measures; Sustainable Development; Testing; Textbooks; Thailand; Toxic effect; Toxicogenomics; Toxicology; Toxin; Trademark; Training; Training and Education; U-Series Cooperative Agreements; Uncertainty; United Nations; United States National Institutes of Health; Universities; Uruguay; Vietnam; Vulnerable Populations; Water Pollution; Weight; Work; World Health Organization; base; biomedical scientist; catalyst; child protection; cost; data collection evaluation; environmental stressor; epidemiology study; experience; follow-up; gene environment interaction; global environment; hazard; health organization; improved; laboratory facility; method development; multidisciplinary; neglect; neurotoxicity; novel strategies; pediatrician; pollutant; programs; prototype; quality assurance; remediation; reproductive; research study; sound; southeast Asian; symposium; tool

DESCRIPTION (provided by applicant) Global environmental health concerns can only be addressed through the cooperative actions of multiple countries and institutions, but this requires effective leadership and coordination. The International Programme on Chemical Safety (IPCS) was established in 1980 as the lead international coordinating body to provide science-based assessments of the potential health risks posed by environmental contaminants. IPCS is managed by the World Health Organization (WHO) but involves many other United Nations, regional, international, national, and non-governmental organizations. IPCS accomplishes most of its work through the efforts of a broad diverse network of internationally recognized scientific experts. The National Institute of Health (NIH)/National Institute of Environmental Health Sciences (NIEHS) played a key role in the formation of IPCS, and NIEHS (intramural and extramural) continues to play a significant leadership role for many IPCS activities. A WHO/IPCS Interregional Research Unit (IRRU) is located on the NIEHS campus to implement the activities supported by the NIEHS-WHO Cooperative Agreement, which addresses the following global cross-cutting environmental health issues: 1) children's health and the environment; 2) toxicogenomics/gene-environment interactions/biomarkers; 3) persistent toxic substances and endocrine disruptors; 4) improved risk assessment methodologies; and 5) development of an integrated risk assessment approach with an emphasis on mixtures. A prototype, step-wise implementation strategy, shown to work very effectively has been developed to implement these aims. This strategy combines a regional approach with a flexible, modular process that allows for uncertainties of unforeseen scientific opportunities, generates unique scientific knowledge, and ultimately leads to the collaboration of research among scientists in developing and developed countries. In addition, this strategy has served as a catalyst for additional multi-partner support and collaborative actions. The activities supported by the Cooperative Agreement result in numerous publications, training of scientists and health care professionals, collaborative research opportunities, generation of unique scientific information and initiation of data collection archives, education, awareness raising, and information dissemination. Countries use these products to put in place evidence based public health, prevention, and remediation policies at the national and regional level.

描述（由申请人提供） 全球环境健康问题只能通过多个国家和机构的合作行动来解决，但这需要有效的领导和协调。 国际化学安全计划（IPC）成立于1980年，是国际领先的协调机构，以对环境污染物带来的潜在健康风险进行基于科学的评估。 IPC由世界卫生组织（WHO）管理，但涉及许多其他联合国，地区，国际，国家和非政府组织。 IPC通过广泛的国际公认科学专家网络的努力来完成大部分工作。 美国国家卫生研究院（NIH）/国家环境卫生学院（NIEHS）在IPC的形成中发挥了关键作用，NIEHS（内部和外壁外）继续在许多IPC活动中发挥重要的领导作用。 WHO/IPC区间研究部门（IRRU）位于NIEHS校园内，以实施NIEHS-WHO合作协议所支持的活动，该协议涉及以下全球跨切割环境健康问题：1）儿童健康和环境； 2）毒理组学/基因环境相互作用/生物标志物； 3）持续的有毒物质和内分泌干扰物； 4）改善风险评估方法； 5）开发综合风险评估方法，重点是混合物。 已经开发了一种非常有效地起作用的原型，逐步实施策略来实施这些目标。 该策略将区域方法与灵活的模块化过程相结合，使不可预见的科学机会不确定性，产生独特的科学知识，并最终导致发展和发达国家科学家之间的研究合作。此外，该策略已成为促进多方支持和协作行动的催化剂。 合作协议支持的活动导致了许多出版物，对科学家和卫生保健专业人员的培训，协作研究机会，独特的科学信息以及数据收集档案的启动，教育，提高意识和信息传播。各国使用这些产品在国家和地区一级制定基于证据的公共卫生，预防和补救政策。