The effect of ART on sexual risk behavior in Chennai, India

ART 对印度金奈危险性行为的影响

• 批准号: 7006316
• 负责人: CAITLIN E KENNEDY
• 金额: $ 4.46万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7006316
• 关键词: AIDS therapy; Africa; HIV infections; adolescence (12-20); adult human (21+); antiAIDS agent; behavioral /social science research tag; clinical research; disease /disorder prevention /control; epidemiology; health behavior; health surveys; high risk behavior /lifestyle; human subject; interview; patient care planning; patient oriented research; predoctoral investigator; sex behavior

DESCRIPTION (provided by applicant): We do not yet know what effect increased access to anti-retroviral therapy (ART) will have on risk behavior in the developing world. This study examines the effect of ART on sexual risk behavior among HIV-positive individuals in Dar es Salaam, Tanzania. A quantitative survey will be administered before individuals initiate ART and again 6 months later. Following the quantitative survey, qualitative interviews will be conducted with selected participants who fall into one of three categories of risk behavior change: positive (less risky), negative (more risky), or no change. Both quantitative and qualitative components will examine sexual risk behavior as well as possible mediating factors between ART and behavior including physical health, psychological health, relational factors, treatment adherence, and treatment optimism. In addition, it is unclear who is receiving limited supplies of ART in resource-poor settings and how these people came to be tested, seek treatment, and be selected to receive ART. A secondary research aim thus seeks to explore the characteristics of people receiving ART in Tanzania. This aim will be accomplished through quantitative, qualitative, and ethnographic methods.

描述（由申请人提供）：我们尚不知道增加抗逆转录病毒治疗 (ART) 的获取会对发展中国家的危险行为产生什么影响。本研究探讨了 ART 对坦桑尼亚达累斯萨拉姆 HIV 阳性个体性危险行为的影响。在个人开始 ART 之前将进行定量调查，并在 6 个月后再次进行。定量调查之后，将对选定的参与者进行定性访谈，这些参与者属于风险行为改变的三类之一：积极（风险较小）、消极（风险较高）或无变化。定量和定性部分都将检查性危险行为以及 ART 和行为之间可能的中介因素，包括身体健康、心理健康、相关因素、治疗依从性和治疗乐观情绪。此外，尚不清楚谁在资源匮乏的环境中接受有限的抗逆转录病毒治疗，以及这些人如何接受检测、寻求治疗并被选择接受抗逆转录病毒治疗。因此，第二个研究目标是探索坦桑尼亚接受抗逆转录病毒疗法的人的特征。这一目标将通过定量、定性和人种学方法来实现。