Training Program in Translational Radiation Oncology

转化放射肿瘤学培训计划

• 批准号: 7273686
• 负责人: MICHAEL E. ROBBINS
• 金额: $ 36.35万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7273686
• 关键词: Radiation Oncology; Training Programs

DESCRIPTION (provided by applicant): There is a growing concern that the failure to train sufficient numbers of basic- and physician-scientists actively engaged in high quality, translational research, will result in the inability of the US to maintain the rate of progress in biomedical research achieved over the past decade. This is particularly true for radiation oncology, where the number of physician-scientists and the number of PhDs in radiation biology, radiation chemistry and radiation physics has decreased significantly over the last 10 or more years. Radiation oncology, biology and physics stand at the threshold of a new, molecular-based approach that promises to utilize the extraordinary advances in radiation delivery, molecular biology and molecular imaging to develop individualized radiation regimes that will significantly affect cancer patient long-term survival and quality of life. However, ensuring the successful development and translation of these advances necessitates the creation of a cadre of basic scientists and radiation oncologists who have a common knowledge base and are dedicated to the pursuit of translational radiation oncology research. To meet these needs, we propose the establishment of a postdoctoral Training Program in Translational Radiation Oncology (TRADONC) research in the Department of Radiation Oncology, Wake Forest University School of Medicine. The major goals of this program are to i] broaden the research infrastructure of translational radiation researchers by increasing the number of well-trained basic scientists and medical physicists exposed to the clinical practice of radiation oncology, and ii] develop a cadre of clinical radiation oncologists proficient in hypothesis-driven basic, translational and clinical research as well as being proficient in the design and implementation of clinical trials. We propose to enroll two trainees each year until 6 are in the program. These trainees will be radiation oncology fellows (MDs) who have completed their residency, postdoctoral basic scientists (PhDs) or postdoctoral medical physicists (PhDs); each trainee will receive support for 3 years. A common didactic curriculum combined with individually tailored formal courses will ensure a common scientific and clinical knowledge base. Moreover, all trainees will receive hands-on experience in both basic laboratory cancer research and clinical research under the guidance of a diverse, interdisciplinary faculty. Over time, this will increase the number of basic research scientists, medical physicists and radiation oncologists able to compete for extramural research funding, as well as increase thenumber and quality of multidisciplinary, translational radiation oncology studies that integrate the lab and clinic

描述（由申请人提供）：越来越担心的是，未能培训足够数量的基本和医师科学家积极从事高质量，转化研究的培训，将导致美国无法维持过去十年来实现生物医学研究的进步率。对于放射肿瘤学尤其如此，在过去的10年或更长时间的时间里，医师科学家的数量以及辐射生物学，辐射化学和放射物理学中的PHD数量显着下降。放射肿瘤学，生物学和物理学处于一种基于分子的新方法的阈值，该方法有望利用辐射递送，分子生物学和分子成像的非凡进步来发展个性化的放射状态，这将显着影响癌症患者的长期生存和生活质量。但是，确保这些进步的成功发展和翻译需要建立拥有常识基础的基础科学家和辐射肿瘤学家的干部，并致力于追求翻译辐射肿瘤学研究。 为了满足这些需求，我们建议在Wake Forest University of Medicine School of Pradiation Oncology系建立一项翻译辐射肿瘤学（TRADONC）研究的博士后培训计划。该计划的主要目标是通过增加培训良好的基础科学家和医学物理学家的数量来扩大转化辐射研究人员的研究基础架构，这些医学家和医学物理学家受到辐射肿瘤学的临床实践的影响，并且II]开发了临床辐射肿瘤学家的干部，培养了熟练的基础，翻译和临床研究，并在设计中实施了熟练的培训和实施。 我们建议每年注册两名学员，直到有6名参加该计划。这些学员将是辐射肿瘤学研究员（MDS），他们已经完成了居住，博士后基础科学家（PHD）或博士后医学物理学家（PHDS）；每个学员将获得3年的支持。一种常见的教学课程，结合了单独量身定制的正式课程，将确保一个常见的科学和临床知识库。此外，在多样化的跨学科教师的指导下，所有学员将在基本实验室癌症研究和临床研究方面获得动手实践经验。随着时间的流逝，这将增加基础研究科学家，医学物理学家和放射肿瘤学家的数量