FASEB Summer Conference on 'Autoimmunity'

FASEB 夏季会议“自身免疫”

基本信息

批准号：
7255748
负责人：
Arlene H Sharpe
金额：
$ 1.5万
依托单位：
FEDERATION OF AMER SOC FOR EXPER BIOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-06-01 至 2010-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7255748
关键词：
Academia Academy Address Affect American Animal Model Antibodies Antigen Presentation Antigen Targeting Apoptosis Area Autoimmune Diseases Autoimmune Process Autoimmunity B cell repertoire B-Lymphocytes Biology Cells Clinical Clinical Trials Collaborations Connective Tissue Data Defect Development Disease Drug Industry Environment Etiology Eye Fostering Generations Genetic Goals Health Heart Immune Immune response Immunologics Immunologist Incidence Industry Inflammation Injury Institutes Insulin-Dependent Diabetes Mellitus International Intervention Joints Length Literature Lupus Lymphocyte Maintenance Medical Mission Molecular Multiple Sclerosis Myocarditis National Institute of Allergy and Infectious Disease National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Mental Health Neuritis Numbers Oral Pancreas Pathogenesis Patients Peripheral Nervous System Population Postdoctoral Fellow Purpose Range Rate Receptors, Antigen, B-Cell Regulation Request for Proposals Research Research Personnel Rheumatoid Arthritis Rivers Role Scientist Self Tolerance Senior Scientist Signal Transduction Site Societies Structure Students T-Cell Development T-Lymphocyte Target Populations Testing Therapeutic Tissues Training United States National Institutes of Health Vermont Woman Women&apos s Health abstracting autoimmune uveitis autoreactive T cell base body system cytokine immune function insight interest lectures men novel strategies posters pre-doctoral programs symposium trafficking

项目摘要

This renewal proposal requests partial support for the 2005, 2007 and 2009 meetings of the Federation of American Societies of Experimental Biology (FASEB) Summer Conference on 'Autoimmunity' which is normally held every other June at the Vermont Academy in Saxtons River, VT. Historically, this meeting has been fully subscribed attracting approximately 200 registrants (the upper limit accommodated at the Vermont venue) and alternates years with the FASEB Summer Conference on 'Lymphocytes and Antibodies'. The purpose of the conference is to bring together basic top immunologists and clinical researchers from academia and the pharmaceutical industry at the professorial, post-doctoral and pre-doctoral levels from around the world to share the latest advancements in understanding of the pathogenesis and regulation of autoimmune disease. Autoimmune diseases together affect approximately 5% of the population targeting every major organ system and thus represent a significant health problem. However, there is not yet clear understanding of their etiologies and at present there are no cures and few useful therapies. The goal of this meeting is to merge data from animal models and patient studies on a broad range of autoimmune diseases; to share recent advances on the development of the T cell and B cell repertoires; mechanisms underlying the establishment and loss of self tolerance; the contribution of genetic and environmental (infectious) triggers to autoimmune disease development and progression; trafficking of autoreactive T cells to sites of inflammation; the pathogenetic mechanisms involved in tissue injury; and the latest therapeutic strategies for regulating autoimmune diseases. A major strength of the meeting is the informal forum that brings students and fellows together with established investigators who are international leaders in this highly disease-relevant and continually growing field. In addition to the oral presentations of the invited speakers and poster presentations by other attendees, the format of the meeting allows two short talks (15 minutes in length), selected from among the submitted abstracts, to be interspersed into each of the eight sessions providing the opportunity for more formalized oral participation by selected graduate student and postdoctoral trainees. A major goal is to foster the initiation and strengthening of collaborations among scientists in the field. This conference serves as the definitive meeting for bringing together basic and clinical scientists with research interests focusing on the etiology and reaulation of autoimmune diseases.

该更新提案要求对2005年，2007年和2009年2005年美国实验生物学联合会（FASEB）夏季会议的“自动免疫”会议进行部分支持，该会议通常在六月在弗吉尼亚州萨克斯顿河的佛蒙特州学院举行。从历史上看，这次会议已被完全订阅，吸引了大约200名注册人（佛蒙特州场地的上限），并在FaseB夏季会议上交替了“淋巴细胞和抗体”。会议的目的是将来自学术界的基本顶级免疫学家和临床研究人员汇集到来自世界各地的教授，博士后和博士前水平的制药行业，以分享了解自身免疫性疾病的发病机理和调节的最新进步。自身免疫性疾病共同影响针对每个主要器官系统的人群的大约5％，因此代表了一个重大的健康问题。但是，目前尚无对其病因的了解，目前尚无治愈方法和有用的疗法。这次会议的目的是合并动物模型的数据和患者研究，以了解广泛的自身免疫性疾病；分享有关T细胞和B细胞库发展的最新进展；建立和丧失自宽容的基础机制；遗传和环境（传染性）触发对自身免疫性疾病发展和进展的贡献；将自动反应性T细胞运输到炎症部位；涉及组织损伤的致病机制；以及调节自身免疫性疾病的最新治疗策略。会议的主要优势是非正式论坛，该论坛将学生和研究员与既定的调查员一起，这些调查员是这个与疾病相关且不断增长的领域的国际领导人。除了其他与会者的口头演讲和海报演讲的口头演讲外，会议的格式还允许两次简短的会谈（长度15分钟），从提交的摘要中选择散布在八个课程中的每个课程中，为选定的研究生和博士后学员提供了更正式的口头参与的机会。一个主要目标是促进该领域科学家之间的合作启动和加强。这次会议是将基础和临床科学家汇集在一起的最终会议，研究兴趣的研究兴趣侧重于自身免疫性疾病的病因和重新出现。