Mobile Elements in the Mammalian Genome

哺乳动物基因组中的移动元素

• 批准号: 7273070
• 负责人: JOHN V. MORAN
• 金额: $ 1.3万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-19 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7273070
• 关键词: Advertising; Agreement; Alu Elements; Area; Attention; Bioinformatics; DNA; Elements; Engineering; Female; Funding; Gene Delivery; Genome; Human Genome; Indium; L1 Elements; Modeling; Mutagens; Numbers; Population Genetics; Principal Investigator; Request for Proposals; Scientist; Structure; Today; Underrepresented Minority; Woman; abstracting; base; genome sequencing; information gathering; male; mammalian genome; rapid growth; response; symposium

DESCRIPTION (provided by applicant): The nine sessions of the conference will be grouped around the following four subject areas: I. Population genetic and evolutionary analysis of mammalian mobile elements a. LINE-1 elements b. Alu elements II. Bioinformatic analysis of mobile elements in whole genome sequences and the impact of repeated DNA on human genome structure/function III. Functional analysis of autonomous and non-autonomous mobile elements a. Mobile elements in model eukaryotic genomes b. Mammalian mobile elements IV. Practical uses for engineered mobile elements a. Transposon mutagens b. Gene delivery agents Agreements to speak have been obtained from the two keynote speakers, all of the session chairs, and many of the speakers. About 12 additional speakers will be chosen from among the conference applicants to present 20-minute talks (including discussion) within the regular scientific sessions. Speakers will be chosen based on submitted abstracts (a fact that will be indicated in the conference advertising). Particular attention will be given in the selection of junior scientists, and women and under-represented minority scientists. This will be the second FASEB conference on the topic of mammalian mobile elements. Because of considerable new information gathered over the past decade, the study of mammalian mobile elements has become a hot topic for a wide variety of biologists and geneticists. The number of principal investigators in this field has expanded from around 5-10 ten years ago to greater than 50 today. In response to this rapid growth, we organized a FASEB meeting on Mobile Elements in Mammalian Genomes, which took place in June 2005. The meeting was attended by eighty-two of our colleagues (56 male and 26 female) and many felt that it was the best meeting they have ever attended on the topic. In this proposal, we request funding for a second meeting on Mobile Elements in Mammalian Genomes to take place in June 2007.

描述（由申请人提供）： 会议的九场会议将围绕以下四个主题领域进行分组： I. 哺乳动物移动元件的群体遗传和进化分析LINE-1 元素 b．铝元素 II.全基因组序列中可移动元件的生物信息分析以及重复DNA对人类基因组结构/功能的影响III。自主和非自主移动元件的功能分析模型真核基因组中的可移动元件 b．哺乳动物移动元件 IV.工程移动元件的实际用途转座子诱变剂 B．基因递送剂 两位主讲人、所有会议主席和许多发言者均已同意发言。将从会议申请者中另外选出约 12 名演讲者，在常规科学会议中进行 20 分钟的演讲（包括讨论）。将根据提交的摘要选择演讲者（这一事实将在会议广告中注明）。将特别关注年轻科学家、女性和代表性不足的少数族裔科学家的选拔。 这将是第二次以哺乳动物移动元件为主题的 FASEB 会议。由于过去十年收集了大量新信息，哺乳动物移动元件的研究已成为众多生物学家和遗传学家的热门话题。该领域的主要研究人员数量已从十年前的约 5-10 人增加到如今的 50 多人。为了应对这种快速增长，我们于 2005 年 6 月组织了一次关于哺乳动物基因组中移动元素的 FASEB 会议。该会议有 82 名同事（56 名男性和 26 名女性）参加，许多人认为这是这是他们参加过的关于该主题的最好的会议。在本提案中，我们请求为 2007 年 6 月举行的第二次哺乳动物基因组移动元素会议提供资金。